Complications of exercise and pharmacologic stress tests: Differences in younger and elderly patients

Journal of Nuclear Cardiology

Volumn 6, Issue 6, 1999, Pages 612-619

  Hashimoto, Akiyoshi ^a   Palmer, Edwin L ^a   Scott, James A ^a   Abraham, Stephen A ^a   Fischman, Alan J ^a   Force, Thomas L ^a   Newell, John B ^a   Rabito, Carlos A ^a   Zervos, Gerasimos D ^a   Yasuda, Tsunehiro ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Adenosine; Adverse effect; Complication of stress test; Dipyridamole; Exercise stress test

Indexed keywords

ADENOSINE; DIPYRIDAMOLE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT;

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; ATRIOVENTRICULAR BLOCK; BLOOD PRESSURE; ELECTROCARDIOGRAM; EXERCISE; FEMALE; FLUSHING; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROVOCATION TEST; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SINUS BRADYCARDIA; SYNCOPE;

EID: 12944262348     PISSN: 10713581     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-3581(99)90098-3     Document Type: Article

References (26)

1. Iskandrian AS, Heo J, Kong B, Lyons E. Effect of exercise level on the ability of thallium-201 tomographic imaging in detecting coronary artery disease: analysis of 461 patients. J Am Coll Cardiol 1989;14: 1477-86.
2. McNeer JF, Margolis JR, Lee KL, Kisslo JA, Peter RH, Kong Y, et al. The role of the exercise test in the evaluation of patients for ischemic heart disease. Circulation 1978;57:64-70.
3. Lam JY, Chaitman BR, Glaenzer M, Byers S, Fite J, Shah Y, et al. Safety and diagnostic accuracy of dipyridamole-thallium imaging in the elderly. J Am Coll Cardiol 1988;11:585-89.
4. Schmucker DL. Age-related changes in drag disposition. Pharmacol Rev 1978;30:445-56.
5. Gerber JG, Brass EP. Drug use. In: Schrier RW, editors. Geriatric medicine. Philadelphia: WB Saunders Co; 1990. p. 91-103.
6. Hazzard WR, Petersdorf RG. Harrison's principles of internal medicine. 10th ed. New York, NY: McGraw-Hill; 1983.
7. Kane RA, Kane RL. Assessing the elderly: A practical guide to management. Lexington, MA: Lexington Books; 1981.
8. Wilson RF, Wyche K, Christensen V, Zimmer S, Laxson DD. Effects of adenosine on human coronary arterial circulation. Circulation 1990;82: 1595-606.
9. Casale PN, Guiney TE, Strauss HW, Boucher CA. Simultaneous low level treadmill exercise and intravenous dipyridamole stress thallium imaging. Am J Cardiol 1988;62:799-802.
10. Rocco TP, Dilsizian V, Strauss HW, Boucher CA. Technetium-99m isonitrile myocardial uptake at rest. II. Relation to clinical markers of potential viability. J Am Coll Cardiol 1989;14:1678-84.
11. Lette J, Tatum JL, Fraser S, Miller DD, Waters DD, Heller G, et al. Safety of dipyridamole testing in 73,806 patients: The multicenter dipyridamole safety study. J Nucl Cardiol 1995;2:3-17.
12. Ranhosky A, Kempthorne-Rawson J. The safety of intravenous dipyridamole thallium myocardium perfusion imaging. Circulation 1990;81: 1205-9.
13. Cerqueira MD, Verani MS, Schwaiger M, Heo J, Iskandrian A. Safety profile of adenosine stress perfusion imaging: results from the adenosine multicenter trial registry. J Am Coll Cardiol 1994;23:384-9.
14. Belardinelli L, Linden J, Berne RM. The cardiac effects of adenosine. Prog Cardiovasc Dis 1989;32:73-97.
15. Lokhanwala MF. Inhibition of cardiac sympathetic neurotransmission by adenosine. Eur J Pharmacol 1979;60:353-7.
16. Wakade AR, Wakade TD. Inhibition of noradrenaline release by adenosine. J Physiol 1978;282:39-49.
17. Glover DK, Ruiz M, Sansoy V, Barrett RJ, Beller GA. Effect of N-0861, a selective adenosine A1 receptor antagonist, on pharmacologic stress imaging with adenosine. J Nucl Med 1995;36:270-5.
18. Verani MS, Mahmarian JJ, Hixson JB, Boyce TM, Staudacher RA. Diagnosis of coronary artery disease by controlled coronary vasodilatation with adenosine and thallium-201 scintigraphy in patients unable to exercise. Circulation 1990;82:80-7.
19. Pennell DJ, Mavrogeni SI, Forbat SM, Karwatowski SP, Underwood SR. Adenosine combined with dynamic exercise for myocardial perfusion imaging. J Am Coll Cardiol 1995;25:1300-9.
20. Cramer MJ, Verzijlbergen MG, van der Wall EE, Vermeersch PH, Niemeyer MG, Zwinderman AH, et al. Comparison of adenosine and high-dose dipyridamole both combined with low-level exercise stress for 99mTc-MIBI SPECT myocardial perfusion imaging. Nucl Med Commun 1996;17:97-104.
21. Craft N, Schwartz JB. Effects of age on intrinsic heart rate, heart rate variability, and AV conduction in healthy humans. Am J Physiol 1995; 268:H1441-H1452.
22. Nishimura S, Kimball KT, Mahmarian JJ, Verani MS. Angiographic and hemodynamic determinants of myocardial ischemia during adenosine thallium-201 scintigraphy in coronary artery disease. Circulation 1993;87:1211-9.
23. Marshall ES, Raichlen JS, Tighe DA, Paul JJ, Breuninger KM, Chung EK. ST-segment depression during adenosine infusion as a predictor of myocardial ischemia. Am Heart J 1994;127:305-11.
24. Braunwald E. Sobel BE. Coronary blood flow and myocardial ischemia. In: Braunwald E, editors. Heart disease, a textbook of cardiovascular medicine. Philadelphia: WB Saunders Co.; 1986. p. 1235-62.
25. Laarman G, Niemeyer MG, van der Wall E, Verzijlbergen FJ, Go TL, Bruschke AV, Ascoop CA. Dipyridamole thallium testing: noncardiac side effects, cardiac effects, electrocardiographic changes and hemodynamic changes after dipyridamole infusion with and without exercise. Int J Cardiol 1988;20:231-8.
26. Kong B, Shaw L, Miler D, Chaitman B. Comparison of accuracy for detecting coronary artery disease and side-effect profile of dipyridamole thallium-201 myocardial perfusion imaging in women versus men. Am J Cardiol 1992;70:168-73.