Meis and Hox: A mighty pair defeats apoptosis

Blood

Volumn 105, Issue 3, 2005, Pages 909-910

  Nakamura, Takuro ^a  

^a CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ETOPOSIDE; HOMEODOMAIN PROTEIN; HOMEODOMAIN PROTEIN HOXA9; HOMEODOMAIN PROTEIN MEIS1; STAUROSPORINE; UNCLASSIFIED DRUG; VALINOMYCIN;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA TRANSCRIPTION; DRUG EFFECT; DRUG MECHANISM; GENE OVEREXPRESSION; HOMEOBOX; LEUKEMOGENESIS; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 12844281745     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-11-4261     Document Type: Review

References (5)

1. Pineault N, Helgason CD, Lawrence HJ, Humphries RK. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol. 2002;30:49-57.
2. Lawrence HJ, Rozenfeld S, Cruz C, et al. Frequent coexpression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias. Leukemia. 1999;13:1993-1999.
3. Nakamura T, Largaespada DA, Shaughnessy JD, Jenkins NA, Copeland NG. Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias. Nat Genet. 1996;12:149-153.
4. Kroon K, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageu G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not PbxIb. EMBO J. 1998;17:3714-3725.
5. Hisa T, Spence SE, Rachel RA, et al. Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J. 2004;23:450-459.