Quantitative determination of dexamethasone in bovine plasma and tissues by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry to monitor residue depletion kinetics

Analytica Chimica Acta

Volumn 529, Issue 1-2 SPEC. ISS., 2005, Pages 361-369

  Cherlet, Marc ^a   De Baere, Siegrid ^a   Croubels, Siska ^a   De Backer, Patrick ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Dexamethasone; Intravenous administration; LC APCI MS MS; Quantification; Residue depletion kinetics; Validation

Indexed keywords

ATMOSPHERIC PRESSURE; BIOLOGICAL ORGANS; EXTRACTION; IONIZATION; LIQUID CHROMATOGRAPHY; MUSCLE; ORGANIC ACIDS; TISSUE;

DEPROTEINIZATION; DEXAMETHASONE (DXM); KIDNEY TISSUES; MAXIMUM RESIDUE LIMIT (MRL);

DRUG PRODUCTS;

ACETIC ACID ETHYL ESTER; DEXAMETHASONE; TRICHLOROACETIC ACID;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; COW; DEPLETION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG TISSUE LEVEL; DRUG WITHDRAWAL; EUROPEAN UNION; FEMALE; INTERMETHOD COMPARISON; KIDNEY PARENCHYMA; KINETICS; LIQUID CHROMATOGRAPHY; LIVER; MALE; MASS SPECTROMETRY; MILK; MUSCLE TISSUE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REACTION TIME; STATISTICAL MODEL; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

BOS TAURUS; BOVINAE;

EID: 12844274548     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2004.07.014     Document Type: Conference Paper

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