A new synthesis of difluoromethanesulfonamides - A novel pharmacophore for carbonic anhydrase inhibition

Organic and Biomolecular Chemistry

Volumn 3, Issue 2, 2005, Pages 222-224

  Boyle, Nicholas A ^a,c   Chegwidden, W Richard ^b,d   Blackburn, G Michael ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^c Biota Research Laboratories (US)   (United States)

^d LAKE ERIE COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; ENZYMES; HYDROPHOBICITY; IONIZATION; ORGANIC ACIDS; PH EFFECTS; SYNTHESIS (CHEMICAL);

GLAUCOMA THERAPY; RETROSYNTHETIC ANALYSIS; WATER SOLUBILITY;

AROMATIC COMPOUNDS;

CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; FLUORINATED HYDROCARBON; ISOENZYME; SULFONAMIDE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; SOLUBILITY; STEREOISOMERISM; SYNTHESIS;

CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; HUMANS; HYDROCARBONS, FLUORINATED; ISOENZYMES; MOLECULAR STRUCTURE; SOLUBILITY; STEREOISOMERISM; SULFONAMIDES;

EID: 12844266171     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b416642f     Document Type: Article

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