Characterization of voltage-dependent gating of P2X2 receptor/channel

European Journal of Pharmacology

Volumn 508, Issue 1-3, 2005, Pages 23-30

  Nakazawa, Ken ^a   Ohno, Yasuo ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Gate; Kinetics; Ligand affinity; P2X receptor; Voltage dependence

Indexed keywords

ADENOSINE TRIPHOSPHATE; PURINE P2X2 RECEPTOR; RECOMBINANT PURINE P2X2 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; ELECTRIC POTENTIAL; HYPERPOLARIZATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; XENOPUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; OOCYTES; RATS; RECEPTORS, PURINERGIC P2; RNA, COMPLEMENTARY; TIME FACTORS; XENOPUS;

EID: 12844263080     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.12.005     Document Type: Article

References (28)

1. 2 receptor immunoreactivity in the dorsal vagal complex and area postrema of the rat Neuroscience 99 2000 683 696
2. A.J. Brake, M.J. Wagenbach, and D. Julius New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor Nature 371 1994 519 523
3. 2 purinoceptor by zinc and pH J. Physiol. 539 2002 347 359
4. T. Egan, and B.S. Khakh Contribution of calcium ions to P2X channel responses J. Neurosci. 24 2004 3413 3420
5. 2 receptors identified by the substituted cysteine accessibility method J. Neurosci. 18 1998 2350 2359
6. 1 receptors J. Biol. Chem. 275 2000 29361 29367
7. P. Fatt, and B.L. Ginsborg The ionic requirements for the production of action potentials in crustacean muscle fibres J. Physiol. 142 1958 516 543
8. W.R. Haines, K. Migita, J.A. Cox, T.M. Egan, and M.M. Voigt The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel J. Biol. Chem. 276 2001 32793 32798
9. B. Hille Classical biophysics of the squid giant axon Ionic channels of excitable membranes Second Edition 1992 Sinauer Sunderland, MA 23 58
10. B. Hille Ligand-gated channels of fast chemical synapses Ionic channels of excitable membranes Second Edition 1992 Sinauer Sunderland, MA 140 169
11. A.L. Hodgkin, and A.F. Huxley The dual effect of membrane potential on sodium conductance in the giant axon of Loligo J. Physiol. 116 1952 497 506
12. L.H. Jiang, F. Rassendren, A. Surprenant, and R.A. North Identification of amino acid residues contributing to the ATP-binding site of a purinergic P2X receptor J. Biol. Chem. 275 2000 34190 34196
13. 2 receptor J. Biol. Chem. 276 2001 14902 14908
14. B.S. Khakh Molecular physiology of P2X receptors and ATP signalling at synapses Nat. Rev. 2 2001 165 174
15. 2 receptor J. Biol. Chem. 276 2001 30934 30941
16. K. Nakazawa, and Y. Ohno Effects of neuroamines and divalent cations on cloned and mutated ATP-gated channels Eur. J. Pharmacol. 325 1997 101 108
17. K. Nakazawa, K. Fujimori, A. Takanaka, and K. Inoue An ATP-activated conductance in pheochromocytoma cells and its suppression by extracellular calcium J. Physiol. 428 1989 257 272
18. 2 purinoceptor/channels Eur. J. Pharmacol. 337 1997 309 314
19. K. Nakazawa, M. Liu, K. Inoue, and Y. Ohno Voltage-dependent gating of ATP-activated channels in PC12 cells J. Neurophysiol. 78 1997 884 890
20. K. Nakazawa, H. Ojima, and Y. Ohno A highly conserved tryptophane residue indispensable for cloned rat neuronal P2X receptor activation Neurosci. Lett. 324 2002 141 144
21. R.A. North Molecular physiology of P2X receptors Physiol. Rev. 82 2002 1013 1067
22. R.A. North, and A. Surprenant Pharmacology of cloned P2X receptors Annu. Rev. Pharmacol. Toxicol. 40 2000 563 580
23. V. Ralevic, and G. Burnstock Receptors for purines and pyrimidines Pharmacol. Rev. 50 1998 413 492
24. F. Rassendren, G. Buell, A. Newbolt, R.A. North, and A. Surprenant Identification of amino acid residues contributing to the pore of a P2X receptor EMBO J. 16 1997 3446 3454
25. 1 receptors. Contribution of aromatic and basic amino acids revealed using mutagenesis and partial agonists J. Biol. Chem. 279 2004 9043 9055
26. M. Rubio, and F. Soto Distinct localization of P2X receptors at excitatory postsynaptic specializations J. Neurosci. 21 2001 641 653
27. W.-M. Weber Ion currents of Xenopus laevis oocytes: state of the art Biochim. Biophys. Acta 1421 1999 213 233
28. Y. Zhang, and O.P. Hamill Calcium, voltage- and osmotic stress sensitive currents in Xenopus oocytes and their relationship to single mechanically gated channels J. Physiol. 523 2000 83 99