Donepezil blocks voltage-gated ion channels in rat dissociated hippocampal neurons

European Journal of Pharmacology

Volumn 508, Issue 1-3, 2005, Pages 15-21

  Yu, Bo ^a   Hu, Guo Yuan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Alzheimer's disease; Cholinesterase inhibitor; Donepezil (E2020); K+ channel; Na + channel

Indexed keywords

DONEPEZIL; INWARDLY RECTIFYING POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; HYPERPOLARIZATION; IC 50; KINETICS; NERVE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; INDANS; ION CHANNELS; KINETICS; MEMBRANE POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; PIPERIDINES; POTASSIUM CHANNELS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 12844257714     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.12.004     Document Type: Article

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