Open-label study of dexmethylphenidate hydrochloride in children and adolescents with attention deficit hyperactivity disorder

Journal of Child and Adolescent Psychopharmacology

Volumn 14, Issue 4, 2005, Pages 555-563

  Silva, Raul ^a   Tilker, Harvey A ^b   Cecil Jr , John T ^b   Kowalik, Sharon ^a   Khetani, Vikram ^c   Faleck, Herbert ^c   Patin, John ^c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Four Rivers Clinical Research   (United States)

^c CELGENE CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANALGESIC AGENT; ANTIASTHMATIC AGENT; ANTIBIOTIC AGENT; ANTITUSSIVE AGENT; AZITHROMYCIN; CEFPROZIL; CETIRIZINE; DECONGESTIVE AGENT; DEXMETHYLPHENIDATE; DIMETAPP; GUAIFENESIN; IBUPROFEN; PARACETAMOL; PROTUSS DM; SALBUTAMOL; TRIAMINIC;

ADOLESCENT; ADULT; ANOREXIA; ARTICLE; ATTENTION DEFICIT DISORDER; ATTENTION DEFICIT DISORDER RATING SCALE; BEHAVIOR DISORDER; CHILD; CLINICAL ARTICLE; CLINICAL GLOBAL IMPRESSION SCALE; CLINICAL TRIAL; CONNERS TEACHER AND PARENT RATING SCALE; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG TOLERABILITY; FEMALE; GENERAL CONDITION IMPROVEMENT; HEADACHE; HUMAN; IRRITABILITY; MALE; MENTAL INSTABILITY; NIGHTMARE; OPEN STUDY; OUTCOMES RESEARCH; PARENT; PILOT STUDY; RATING SCALE; SIDE EFFECT; STOMACH PAIN; SULLENNESS; TEACHER; VISUAL ANALOG SCALE; VOMITING; WEIGHT GAIN; WEIGHT REDUCTION;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; METHYLPHENIDATE; PILOT PROJECTS; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; STEREOISOMERISM; TREATMENT OUTCOME;

EID: 12744279310     PISSN: 10445463     EISSN: None     Source Type: Journal    
DOI: 10.1089/cap.2004.14.555     Document Type: Article

References (9)

1. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. (DSM-IV). Washington (DC) American Psychiatric Association, 1994.
2. Ding Y-S, Fowler JS, Volkow ND, Dewey SL, Wang G-J, Logan J, Gatley SJ, Pappas N: Chiral drugs: Comparison of the pharmacokinetics of [11C]d-threo and 1-threo-methylphenidate in the human and baboon brain. Psychopharmacology 131:71-78, 1997.
3. Greene RW, Biederman J, Faraone SV, Ouellette CA, Penn C, Griffin SM: Toward a new psychometric definition of social disability in children with attention deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 35:571-578, 1996.
4. Guy W: Clinical global impressions scale (CGI). In: American Psychiatric Association. Task Force for the Handbook of Psychiatric Measures. Handbook of Psychiatric Measures. Washington, (DC) American Psychiatric Association, pp. 100-102, 2000.
5. Patrick KS, Caldwee RW, Ferris RM, Breese GR: Pharmacology of the enantiomers of threomethylphenidate. J Pharmacol Exp Ther 241:152-158, 1987.
6. Rohde LA, Beiderman J, Busnello EA, Zimmerman H, Schmitz M, Martins S, Tramontina S: ADHD in a school sample of Brazilian adolescents: A study of prevalence, comorbid conditions, and impairments. J Am Acad Child Adolesc Psychiatry 38:716-722, 1999.
7. Srinivas NR, Hubbard JW, Quinn D, Midha KK: Enantioselective pharmacokinetics and pharmacodynamics of dl-threo-methylphenidate in children with attention deficit hyperactivity disorder. Clin Pharmacol Ther 52:561-568, 1992.
8. Swanson J, Gupta S, Guinta D, Flynn D, Agler D, Lerner M, Williams L, Shouslon I, Wigal S: Acute tolerance of methylphenidate in the treatment of attention deficit hyperactivity disorder in children. Clin Pharmacol Ther 66:295-305, 1999.
9. Wigal S, Swanson JM, Feifel D, Sangal RB, Elia J, Casat CD, Zeldis JB, Conners CK: A double-blind, placebo-controlled trial of dexmethylphenidate hydrochloride in children with attention-deficit/ hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 43:1406-1414, 2004.