A peptide-catalyzed asymmetric Stetter reaction

Chemical Communications

Volumn , Issue 2, 2005, Pages 195-197

  Mennen, Steven M ^a   Blank, Jarred T ^a   Tran Dubé, Michelle B ^a   Imbriglio, Jason E ^a   Miller, Scott J ^a  

^a BOSTON COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE DERIVATIVE; PEPTIDE; THIAZOLYLALANINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CYCLIZATION; ENANTIOMER; ENANTIOSELECTIVITY; REACTION ANALYSIS; STETTER REACTION;

EID: 12744273171     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b414574g     Document Type: Article

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22. 2) to the reaction conditions leads to a reduction in ee of the product over time.
23. -1,3450 reflections collected (R1 = 0.0190, wR2 = 0.0477), 2761 independent reflections (R(int) = 0.0300, R1 = 0.0190, wR2 = 0.0477)‡.
24. This work was supported by the U.S. National Science Foundation (CHE-0236591). We are grateful to Merck and Pfizer for additional support, and to Synthetech (Albany, OR) for a generous donation of Taz.