A 10 year retrospective audit of long-term apomorphine use in Parkinson's disease

Journal of Neurology

Volumn 251, Issue 11, 2004, Pages 1370-1374

  Tyne, Hilary L ^a   Parsons, Jan ^b   Sinnott, Ann ^b   Fox, Susan H ^b   Fletcher, Nicholas A ^b   Steiger, Malcolm J ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b WALTON CENTRE FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Apomorphine; Motor fluctuations; Parkinson's disease

Indexed keywords

APOMORPHINE;

ADULT; AGED; ANEMIA; ARTICLE; CONFUSION; CONTROLLED STUDY; COOMBS TEST; DISEASE DURATION; DOSE RESPONSE; DRUG EFFICACY; DRUG INTERMITTENT THERAPY; DRUG SAFETY; DYSKINESIA; FEMALE; HALLUCINATION; HUMAN; HYPOTENSION; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MOTOR DYSFUNCTION; NAUSEA; PARKINSON DISEASE; PRIORITY JOURNAL; SKIN DISEASE; TREATMENT INDICATION;

ADULT; AGED; ANTIPARKINSON AGENTS; APOMORPHINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PARKINSON DISEASE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 12744260002     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-004-0547-4     Document Type: Article

References (21)

1. Anden NE, Rubenson A, Fuxe K, et al. (1967) Evidence for dopamine receptor stimulation by apomorphine. J Pharmac Pharmacol 19:627-629
2. Cantello R, Gilli M, Riccio A, Bergamasco B (1986) Mood changes associated with "end of dose deterioration" in Parkinson's disease: a controlled study. J Neurol Neurosurg Psychiatry 49:1182-1190
3. Colzi A, Turner K, Lees AJ (1998) Continuous subcutaneous waking day apomorphine in the long-term treatment of levodopa induced interdose dyskinesias in Parkinson's disease. J Neurol NeurosurgPsychiatry 64:573-576
4. Corsini GU, Del Zompo M, Gessa GL, Mangoni A (1979) Therapeutic efficacy of apomorphine combined with an extracerebral inhibitor of dopamine receptors in Parkinson's disease. Lancet 1:954-956
5. Cotzias GC, Papavasiliou PS, Tolosa ES, Mendez JS, Bell-Midura M (1976) Treatment of Parkinson's disease with aporphines. Possible role of growth hormone. N Engl J Med 294(11):567-572
6. Dewey Jr RB, Hutton JT, LeWitt PA, Factor SA (2001) A randomized double-blind, placebo controlled trial of subcutaneously injected apomorphine for Parkinsonian off states. Arch Neurol 58:1385-1392
7. Ernst AM (1967) Mode of action of apomorphine and dexamphetamine in gnawing compulsion in rats. Psychopharmacologia 10(4):316-323
8. Frankel JP, Lees AJ, Kempster PA, Stern GM (1990) Subcutaneous apomorphine in the treatment of Parkinson's disease. J Neurol Neurosurg Psychiatry 53(2):96-101
9. Hardie RJ, Lees AJ, Stern GM (1984) On-Off fluctuations in Parkinson's disease. A clinical and neuropharmacological study. Brain 107:487-506
10. Kumar R, Lozano A, Kim YJ, et al. (1998) Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease. Neurology 51:850-855
11. Manson AJ, Turner K, Lees AJ (2002) Apomorphine monotherapy in the treatment of refractory motor complications of Parkinson's disease: long-term follow-up study of 64 patients. Mov Disord 17:1235-1241
12. Marsden CD, Parkes JD (1976) "On-Off" effects in patients with Parkinson's disease on chronic levodopa therapy Lancet 1:292-296
13. Marsden CD, Parkes JD (1977) Success and problems of long-term levodopa therapy in Parkinson's disease. Lancet i:345-349
14. Quinn NP, Koller WC, Lang AE, Marsden CD (1986) Painful Parkinson's disease. Lancet 1:1366-1369
15. Schwab RS, Amador LV, Lettvin JY (1951) Apomorphine in Parkinson's disease. Transf Am Neurol Assoc 76:251-253
16. Shaw KM, Lees AJ, Stern GM (1980) The impact of treatment with levodopa on Parkinson's disease. QJM 49:283-293
17. Steiger MJ, Quinn NP, Marsden CD (1992) The clinical use of apomorphine in Parkinson's disease. J Neurol 239:389-393
18. Stibe CM, Lees AJ, Kempster PA, Stern GM (1988) Subcutaneous apomorphine in parkinsonian on- off oscillations. Lancet 1:403-406
19. Stocchi F, Vacca L, De Pandis MF, Barbato L, Valente M, Ruggieri S (2001) Subcutaneous continuous apomorphine infusion in fluctuating patients with Parkinson's disease: long-term results. Neurol Sci 22:93-94
20. Varma TR, Fox SH, Eldridge PR, et al. (2003) Deep brain stimulation of the subthalamic nucleus: effectiveness in advanced Parkinson's disease patients previously reliant on apomorphine. J Neurol Neurosurg Psychiatry 74:170-174
21. Weil E (1884) De l'apomorphine dans certain troubles nerveux. Lyon Med 48:411-419