Prolonged effect of troglitazone (CS-045) on xenograft survival of hybrid artificial pancreas

Cell Transplantation

Volumn 6, Issue 5, 1997, Pages 547-550

  Kawakami, Yoshiyuki ^a   Inoue, Kazutomo ^a   Tun, Tein ^a   Hayashi, Hiroyuki ^a   Setoyama, Hiroshi ^a   Gu, Y J ^a   Cui, W X ^a   Imamura, Masayuki ^a   Iwata, Hiroo ^a   Ikada, Yoshito ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Antidiabetic agent; Biohybrid artificial pancreas; Islet xeno transplantation; Troglitazone (CS 045)

Indexed keywords

AGAROSE; CARBOXYMETHYLCELLULOSE; GLUCOSE; HEXADIMETHRINE BROMIDE; INSULIN; ORAL ANTIDIABETIC AGENT; POLYSTYRENESULFONIC ACID; STREPTOZOCIN; TROGLITAZONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL PANCREAS; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GRAFT SURVIVAL; HYBRID; INSULIN RESPONSE; INSULIN SENSITIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; MICROENCAPSULATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; XENOGRAFT;

ANIMALS; BLOOD GLUCOSE; CAPSULES; CHROMANS; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; GRAFT SURVIVAL; HYPOGLYCEMIC AGENTS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, INBRED BALB C; PANCREAS, ARTIFICIAL; RATS; RATS, SPRAGUE-DAWLEY; THIAZOLES; THIAZOLIDINEDIONES; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA;

EID: 12644305890     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0963-6897(97)00075-4     Document Type: Article

References (8)

1. Fujiwara, T.; Yoshioka, S.; Yoshioka, T.; Ushiyama, L; Horikoshi, H. Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats. Diabetes 37:1549-1558; 1988.
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4. Kellerer, M.; Kroder, G.; Tippmer, S.; Berti, L.; Kiehn, R.; Mosthaf, L.; Haring, H. Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts. Diabetes 43:447-453; 1994.
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6. O'Shea, G.M.; Sun, A.M. Encapsulation of rat islets of Langerhans prolongs xenograft survival in diabetic mice. Diabetes 35:943-946; 1986.
7. Tein, T.; Inoue, K.; Hayashi, H.; Tun, A.; Gu, Y.J.; Doi, R.; Kaji, H.; Echigo, Y.; Wang, W.J.; Setoyama, H.; Imamura, M.; Maetani, S.; Morikawa, N.; Iwata, H.; Ikada, Y. A newly developed three-layer agarose microcapsule for a promising biohybrid artificial pancreas; rat to mouse xenotransplantation. Cell Transplant. 5:59-63; 1996.
8. Van der Vliet, J.A.; Meloche, R.M.; Chen, D.; Kaufman, D.B.; Sutherland D.E.R. Pancreatic islet isolation in rats with ductal collagenase digestion, stationary digestion, and dextran separation. Transplantation 45:493-495; 1988.