Fusaricide, a new cytotoxic N-hydroxypyridone from Fusarium sp.

Journal of Natural Products

Volumn 59, Issue 12, 1996, Pages 1151-1153

  McBrien, Kimberly D ^a   Gao, Qi ^a   Huang, Stella ^a   Klohr, Steven E ^a   Wang, Richard R ^a   Pirnik, Dolores M ^a   Neddermann, Kim M ^a   Bursuker, Isia ^a   Kadow, Kathleen F ^a   Leet, John E ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUSARICIDE; PYRIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; FUSARIUM; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BENZOPYRANS; CRYSTALLOGRAPHY, X-RAY; FUNGI; FUSARIUM; GENE EXPRESSION REGULATION, VIRAL; MICROBIAL SENSITIVITY TESTS; PYRIDONES; TUMOR CELLS, CULTURED; VIRION;

EID: 12644299592     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np960521t     Document Type: Article

References (18)

1. Zapp, M. L.; Stern, S.; Green, M. R. Cell. 1993, 74, 969-978.
2. Bartel, D. P.; Zapp, M. L.; Green, M. R.; Szostak, J. W. Cell. 1991, 67, 529-536.
3. Cook, K. S.; Fisk, G. J.; Hauber, J.; Usman, N.; Daly, T. J.; Rusche, J. R. Nucleic Acids Res. 1991, 19, 1577-1583.
4. Daly, T. J.; Cook, K. S.; Gray, G. S.; Malone, T. E.; Rusche, J. R. Nature. 1989, 342, 816-819.
5. Zapp, M. L.; Green, M. R. Nature. 1989, 342, 714-716.
6. Peabody, D. S. J. Biol. Chem. 1990, 265, 5684-5689.
7. Qian-Cutrone, J.; Huang, S.; Trimble, J.; Li, H.; Lin, P.-F.; Alam, M.; Klohr, S. E.; Kadow, K. F. J. Nat. Prod. 1996, 59, 196-199.
8. Qian-Cutrone, J.; Huang, S.; Chang, L.-P.; Pirnik, D.; Klohr, S. E.; Dalterio, R. A.; Hugill, R.; Lowe, S.; Alam, M.; Kadow, K. F. J. Antibiot., 1996, 49, accepted for publication.
9. McBrien, K. D.; Berry, R. L.; Lowe, S. E.; Neddermann, K. M.; Bursuker, I.; Huang, S.; Klohr, S. E.; Leet, J. E. J. Antibiot., 1995, 48, 1446-1452.
10. TePaske, M. R.; Gloer, J. B.; Wicklow, D. T.; Dowd, P. F. Tetrahedron Lett., 1991, 32, 5687-5690.
11. Snider, B. B.; Lu, Q. Tetrahedron Lett., 1994, 35, 531-534.
12. Teshima, Y.; Shin-ya, K.; Shimazu, A.; Furihata, K.; Chul, H. S.; Furihata, K.; Hayakawa, Y.; Nagai, K.; Seto, H. J. Antibiot. 1991, 44, 685-687.
13. Hosaya, R.; Yugami, T.; Yoshida, S.; Yaguchi, T.; Komuro, K.; Sasaki, T. Japanese Patent 07,267,962-A; Chem. Abstr. 1996, 124, 143744k.
14. Hawksworth, D. L.; Kirk, P. M.; Sutton, B. C.; Pegler, D. N. (1995). Ainsworth & Bisby's Dictionary of the Fungi, 8th Ed. CAB International, Wallingford, UK, 1995.
15. Nirenberg, H. I. Can. J. Bot. 1980, 59, 1599-1609.
16. Joffe, A. Z. Mycologia applicata 1974, 53, 201-228.
17. Fair, C. K. (1990). MolEN. An Interactive Intelligent System for Crystal Structure Analysis. Enraf-Nonius, Delft, The Netherlands.
18. Atomic coordinates, thermal parameters, bond lengths and angles have been deposited with the Cambridge Crystallographic Data Center and can be obtained, upon request, from Dr. Olga Kennard, University Chemical Laboratory, 12 Union Road, Cambridge Cb2 1EZ, UK.