Sodium 2,3-dimercaptopropane-1-sulfonate challenge test for mercury in humans. III. Urinary mercury after exposure to mercurous chloride

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 2, 1996, Pages 938-944

  Maiorino, Richard M ^b   Gonzalez Ramirez, Diego ^a   Zuniga Charles, Miguel ^a   Xu, Zhaofa ^b   Hurlbut, Katherine M ^d   Aposhian, Mary M ^b   Dart, Richard C ^d   Woods, James S ^e,f   Ostrosky Wegman, Patricia ^g   Gonsebatt, Maria E ^g   Aposhian, H Vasken ^a,b,c  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b University of Arizona   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d ROCKY MOUNTAIN POISON AND DRUG CENTER   (United States)

^e BATTELLE MEMORIAL INSTITUTE   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

^g INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD; MERCUROUS CHLORIDE; MERCURY; UNITHIOL;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GENOTOXICITY; HUMAN; INDUSTRIAL WORKER; INTOXICATION; MALE; MERCURIALISM; OCCUPATIONAL EXPOSURE; OCCUPATIONAL TOXICOLOGY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TOXICOKINETICS; URINARY EXCRETION;

ADULT; AGED; BODY BURDEN; CHELATING AGENTS; FEMALE; HUMANS; LEAD; MALE; MERCURIC CHLORIDE; MERCURY; MERCURY COMPOUNDS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; UNITHIOL;

EID: 12644292901     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. APOSHIAN, H. V.: DMSA and DMPS - Water soluble antidotes for heavy metal poisoning. Annu. Rev. Pharmacol. Toxicol. 23: 193-215, 1983.
2. APOSHIAN, H. V., BRUCE, D. C., ALTER, W., DART, R. C., HURLBUT, K. M. AND APOSHIAN, M. M., Urinary mercury after administration of 2,3-dimercaptopropane-1-sulfonic acid: Correlation with dental amalgam score. Fed. Am. Soc. Exp. Biol. J. 6: 2472-2476, 1992a.
3. APOSHIAN, H. V., GONZALEZ-RAMIREZ, D., MAIORINO, R. M., ZUNIGA-CHARLES, M., XU, Z-F., HURLBUT, K. M., JUNCO-MUNOZ, P., APOSHIAN, M. M. AND DART, R. C.: Mobilization of heavy metals by newer, therapeutically useful chelating agents. Toxicology 97: 23-38, 1995.
4. APOSHIAN, H V., MAIORINO, R. M., RIVERA, M., BRUCE, D. C., DART, R. C., HURLBUT, K. M., LEVINE, D. J., ZHENG, W., FERNANDO, Q., CARTER, D. AND APOSHIAN, M. M.: Human studies with the chelating agents, DMPS and DMSA. Clin. Toxicol. 30: 505-528, 1992b.
5. CAMPBELL, J. R., CLARKSON, T. W. AND OMAR, M. D.: The therapeutic use of 2,3-dimercaptopropane-1-sulfonate in two cases of inorganic mercury poisoning. J. Am. Med. Assoc 256: 3127-3130, 1986.
6. CHERIAN, M. G., MILES, E. F., CLARKSON, T. W. AND COX, C.: Estimation of mercury burdens in rats by chelation with dimercaptopropane sulfonate. J. Pharmacol. Exp. Ther. 245: 479-484, 1988.
7. CHISOLM, J. J., JR.: Mobilization of lead by calcium disodium edetate; a reappraisal (Editorial). Am. J. Dis. Child. 141: 1256-1257, 1987.
8. CHISOLM, J. J., JR. AND THOMAS, D. J.: Use of 2,3-dimercaptopropane-1-sulfonate in treatment of lead poisoning in children. J. Pharmacol. Exp. Ther. 235: 665-669, 1985.
9. CLARKSON, T. W., HURSH, J. B., SAGER, P. R. AND SYVERSEN, T. L. M.: Mercury. In Biological Monitoring of Toxic Metals, ed. by T. W. Clarkson, L. Friberg, G. F. Nordberg and P. R. Sager, pp. 204-205, Plenum Press, New York, 1988.
10. CLARKSON, T. W., MAGOS, L., COX, C., GREENWOOD, M. R., AMINI-ZAK, L., MAJEED, M. A. AND AL-DAMLUJI, S. F.: Tests of efficacy of antidotes for removal of methyl mercury in human poisoning during the Iraq outbreak. J. Pharmacol. Exp. Ther. 218: 74-83, 1981.
11. DEAN, R. B. AND DIXON, W. J.: Simplified statistics for small numbers of observations. Anal. Chem. 23: 636-638, 1951.
12. FINGL, E.: Cathartics and laxatives. In The Pharmacological Basis of Therapeutics, 4th ed., ed. by L. S. Goodman and A. Gilman, p. 1028, The MacMillan Co., Toronto, 1970.
13. GERHARD, I., WALDBRENNER, P., THRUO, H. AND RUNNEBAUM, B.: Diagnosis of heavy metal loading by the oral DMPS and chewing-gum tests. Klin. Lab. 38: 404-411, 1992.
14. GODLEE, F.: Skin lighteners cause permanent damage. Br. Med. J. 305: 333, 1992.
15. GONZALEZ-RAMIREZ, D., MAIORINO, H. M., ZUNIGA-CHARLES, M., XU, Z., HURLBUT, K. M., JUNCO-MUNOZ, P., APOSHIAN, M. M., DART, R. C., GAMA, J. H. D., ECHEVERRIA, D., WOODS, J. S. AND APOSHIAN, H. V.: Sodium 2,3-dimercaptopropane-1-sulfonate challenge test for mercury in humans. II. Urinary mercury, porphyrins and neurobehavioral changes of dental makers in Monterrey, Mexico. J. Pharmacol. Exp. Ther. 272: 264-274, 1995.
16. HAND, W. C., EDWARDS, B. B. AND CALEY, E. R.: Studies in the pharmacology of mercury. III. Histochemical demonstration and differentiation of metallic mercury, mercurous mercury, and mercuric mercury. J. Lab. Clin. Med. 1835-1841, 1943.
17. HENDRY, W. F., A'HERN, R. P. AND COLE, P. J.: Was Young's syndrome caused by exposure to mercury in childhood? Br. Med. J 307: 1579-1582, 1993.
18. HURLBUT, K. M., MAIORINO, R. M., MAYERSOHN, M., DART, R. C., BRUCE, D. C. AND APOSHIAN, H. V.: Determination and metabolism of dithiol chelating agents. XVI. Pharmacokinetics of sodium 2,3-dimercapto-1-propanesulfonate after intravenous administration to human volunteers. J. Pharmacol. Exp. Ther. 268: 662-668, 1994.
19. KANG-YUM, E. AND ORANSKY, S.: Chinese patent medicine as a potential source of mercury poisoning. Vet. Hum. Toxicol. 34: 235-238, 1992.
20. KEMPER, F. H., JEKAT, F. W., BERTRAM, H. P. AND ECKARD, R.: New chelating agents. In Basic Science in Toxicology, Proceedings of the 5th International Congress of Toxicology, England, 1989, ed. by G. N. Volans, J. Sims, F. M. Sullivan and P. Turner, Taylor & Francis Ltd., London, Great Britain, 1990.
21. KEW, J., MORRIS, C., AIHIE, A., FYSH, R., JONES, S. AND BROOKS, D.: Arsenic and mercury intoxication due to Indian ethnic remedies. Br. Med. J. 306: 506-507, 1993.
22. KLIMOVA, K. K.: Pharmacology of a new Unithiol antidote. Farmakol. Toksikol (Moscow) 21: 53-59, 1958.
23. MAIORINO, R. M., DART, R. C., CARTER, D. E. AND APOSHIAN, H. V.: Determination and metabolism of dithiol chelating agents. XII. Metabolism and pharmacokinetics of sodium 2,3-dimercaptopropane-1-sulfonate in humans. J. Pharmacol. Exp. Ther. 259: 808-814, 1991.
24. MOLIN, M., SCHUTZ, A., SKERFVING, S. AND SALLSTEN, G.: Mobilized mercury in subjects with varying exposure to elemental mercury vapour. Int. Arch. Occup. Environ. Health 63: 187-192, 1991.
25. MOORE, D. F., O'CALLAGHAN, C. A., BERLYNE, G., OGG, C. S., DAVIES, H. A., HOUSE, I. M. AND HENRY, J. A.: Acute arsenic poisoning: Absence of polyneuropathy after treatment with 2,3-dimercaptopropanesulfonate (DMPS). J. Neurol. Neurosurg. Psych. 57: 1133-1135, 1994.
26. OSINSKA, J. AND TROJANOWSKA, B.: The clinical state of persons with the mercury deposits detected by the use of the unithiol test. Przeglad Lekarski 38: 595-598, 1981.
27. SALLSTEN, G., BARREGARD, L. AND SCHUTZ, A.: Clearance half life of mercury in urine after the cessation of long term occupational exposure: Influence of a chelating agent (DMPS) on excretion of mercury in urine. Occup Environ. Med. 51: 337-342, 1994.
28. SARTO, F , FINOTTO, S., GLACOMELLI, L., MAZZOTTI, D., TOMANIN, R. AND LEVIS, A.: The micronuclei assay in exfoliated cells of the human buccal mucosa. Mutagenesis 2: 11-17, 1987.
29. SCHIELE, R., SCHALLER, K. H. AND WELTLE, D.: Mobilization of mercury reserves in the organism by means of DMPS (Dimaval). Occup. Med. Soc. Med. Prevent. Med. 24: 249-251, 1989.
30. STICH, H., SAN, R. AND ROSIN, M.: Adaptation of the DNA-repair and micronucleus test to human cell suspensions and exfoliated cells. Ann. N.Y. Acad. Sci. 407: 93-105, 1983.
31. STICH, H. AND ROSIN, M.: Quantitating the synergistic effect of smoking and alcohol consumption with the micronucleus test on human buccal mucosa cells. Int. J. Cancer 31: 305-308, 1983.
32. TOLBERT, P. B., EHY, C. M. AND ALLON, J. W.: Micronuclei and other anomalies in buccal smears methods' development. Mutat. Res. 271: 69-77, 1992
33. WARKANY, J. AND HUBBARD, D. M: Adverse mercurial reactions in the form of acrodynia and related conditions. Am J. Dis. Child 81: 335-373, 1951.
34. WEISS, S. W., WANDS, J. R. AND YARDLEY, J. H.: Demonstration by electron diffraction of black mercuric Sulfide (β-HgS) in a case of "melanosis coli and black kidneys" caused by chronic inorganic mercury poisoning (Abstract). Lab. Invest. 401-402, 1973.
35. ZINTERHOFER, L. J. M., JATLOW, P. I. AND FAPPIANO, A.: Atomic absorption determination of lead in blood and urine in the presence of EDTA. J. Lab. Clin. Med. 78: 664-674, 1971.