A randomized trial comparing cyclosporine induction with sequential therapy in renal transplant recipients

American Journal of Kidney Diseases

Volumn 30, Issue 5, 1997, Pages 639-645

  Kasiske, Bertram L ^a   Johnson, Heather J ^b   Goerdt, Paul J ^b   Heim Duthoy, Karen L ^b   Rao, Venkateswara K ^b   Dahl, David C ^b   Ney, Arthur L ^b   Andersen, Robert C ^b   Jacobs, Donald M ^b   Odland, Mark D ^b  

^a HENNEPIN COUNTY MEDICAL CENTER   (United States)

^b NONE

Author keywords

Anti thymocyte globulin; Cyclosporine; Induction; Renal transplantation

Indexed keywords

CYCLOSPORIN A; DILTIAZEM; THYMOCYTE ANTIBODY;

ADULT; ARTICLE; CADAVER KIDNEY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GRAFT FAILURE; HISTOINCOMPATIBILITY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY DONOR; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; SUSTAINED RELEASE PREPARATION;

EID: 12644276404     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-6386(97)90487-X     Document Type: Article

References (23)

1. The Canadian Multicentre Transplant Study Group: A randomized clinical trial of cyclosporine in cadaveric renal transplantation. N Engl J Med 314:1219-1225, 1986
2. European Multicenter Trial Group: Cyclosporin in cadaveric renal transplantation: One-year follow-up of a multicentre trial. Lancet 2:986-989, 1983
3. Homan WP, Fabre JW, Williams KA, Millard PR, Morris PJ: Studies on the immunosuppressive properties of cyclosporin A in rats receiving renal allografts. Transplantation 29:361-366, 1980
4. Najarian JS, Fryd DS, Strand M, Canafax DM, Ascher NL, Payne WD, Simmons RL, Sutherland DER: A single institution, randomized, prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients. Ann Surg 201:142-157, 1985
5. Michael HJ, Francos GC, Burke JF, Besarab A, Moritz M, Gillum D, Jarrell B: A comparison of the effects of cyclosporine versus antilymphocyte globulin on delayed graft function in cadaver renal transplant recipients. Transplantation 48:805-808, 1989
6. Evans RW, Manninen DL, Dong FB, Ascher NL, Frist WH, Hansen JA, Kirklin JK, Perkins JD, Pirsch JD, Sanfilippo FP: Immunosuppressive therapy as a determinant of transplantation outcomes. Transplantation 55:1297-1305, 1993
7. Powelson JA, Cosimi AB: Antilymphocyte globulin and monoclonal antibodies, in Morris PJ (ed): Kidney Transplantation Principles and Practice (ed 4). Philadelphia, PA, Saunders, 1994, pp 215-232
8. Chagnac A, Zevin D, Ori Y, Korzets A, Hirsh J, Levi J: The effect of high-dose nifedipine on renal hemodynamics of cyclosporine-treated renal allograft recipients. Transplantation 53:766-769, 1992
9. Sørensen SS, Skovbon H, Eiskjaer H, Thomsen K, Pedersen EB: Effect of felodipine on renal haemodynamics and tubular sodium handling in cyclosporin-treated renal transplant recipients. Nephrol Dial Transplant 7:69-78, 1992
10. Suthanthiran M, Haschemeyer RH, Riggio RR, Adubor C, Friedman GS, Cheigh JS, Wang JC, Fotino M, Stubenbord WT, Saal SD, Stenzel KH, Rubin AL: Excellent outcome with a calcium channel blocker-supplemented immunosuppressive regimen in cadaveric renal transplantation. Transplantation 55:1008-1013, 1993
11. Khauli RB, Wilson JM, Baker SP, Valliere SA, Lovewell TD, Stoff JS: Triple therapy in cadaveric renal transplantation: Role of induction cyclosporine and targeted levels to avoid rejection. J Urol 153:1805-1810, 1995
12. Dawidson I, Rooth P, Lu C, Sagalowsky A, Diller K, Palmer B, Peters P, Risser R, Sandor Z, Seney F: Verapamil improves the outcome after cadaver renal transplantation. J Am Soc Nephrol 2:983-990, 1991
13. Neumayer HH, Kunzendorf U, Schreiber M: Protective effects of calcium antagonists in human renal transplantation. Kidney Int 41:S-87-S-93, 1992 (suppl 36)
14. Chrysostomou A, Walker RG, Russ GR, d'Apice AJF, Kincaid-Smith P, Mathew TH: Diltiazem in renal allograft recipients receiving cyclosporine. Transplantation 55:300-304, 1993
15. Harper SJ, Moorhouse J, Abrams K, Jurewicz A, Nicholson M, Horsburgh T, Harris K, Combe C, Bell PRF, Walls J, Donnelly PK, Veitch PS, Feehally J: The beneficial effects of oral nifedipine on cyclosporin-treated renal transplant recipients - A randomised prospective study. Transplant Int 9:115-125, 1996
16. Alcaraz A, Oppenheimer F, Talbot-Wright R, Fernández-Cruz L, Mañalich M, García-Pagés E, Cetina A, Vendrell JR, Carretero P: Effect of diltiazem in the prevention of acute tubular necrosis, acute rejection, and cyclosporine levels. Transplant Proc 23:2383-2384, 1991
17. Pirsch JD, D'Alessandro AM, Roecker EB, Knechtle SJ, Reed A, Sollinger HW, Kalayoglu M, Belzer FO: A controlled, double-blind, randomized trial of verapamil and cyclosporine in cadaver renal transplant patients. Am J Kidney Dis 21:189-195, 1993
18. Ladefoged SD, Pedersen E, Hammer M, Rasmussen KC, Hansen FM, Andersen CB: Influence of diltiazem on renal function and rejection in renal allograft recipients receiving triple-drug immunosuppression: A randomized, double-blind, placebo-controlled study. Nephrol Dial Transplant 9:543-547, 1994
19. Wilkie ME, Beer JC, Evans SJW, Raftery MJ, Lord RHH, Moore R, Marsh FP: A double-blind, randomized, placebo-controlled study of nifedipine on early renal allograft function. Nephrol Dial Transplant 9:800-804, 1994
20. Norusis MJ: Statistical Package for the Social Sciences (SPSS/PC+ V2.0): Base Manual. Chicago, IL, SPSS Inc, 1988
21. Brockmöller J, Neumayer HH, Wagner K, Weber W, Heinemeyer G, Kewitz H, Roots I: Pharmacokinetic interaction between cyclosporin and diltiazem. Eur J Clin Pharmacol 38:237-242, 1990
22. Weir MR, Peppler R, Gomolka D, Handwerger BS: Additive inhibition of afferent and efferent immunological responses of human peripheral blood mononuclear cells by verapamil and cyclosporine. Transplantation 51:851-857, 1991
23. Dumont L, Chen H, Daloze P, Xu D, Garceau D: Immunosuppressive properties of the benzothiazepine calcium antagonists diltiazem and clentiazem, with and without cyclosporine, in heterotopic rat heart transplantation. Transplantation 56:181-184, 1993