메뉴 건너뛰기




Volumn 26, Issue 1, 1997, Pages 27-33

Enhanced G-protein-induced relaxation in portal hypertensive rats: Role of nitric oxide

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; NITRIC OXIDE;

EID: 12644274639     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510260104     Document Type: Article
Times cited : (10)

References (45)
  • 1
    • 0025294022 scopus 로고
    • Liver function and pharmacological considerations in the pathogenesis and treatment of portal hypertension
    • Reichen J. Liver function and pharmacological considerations in the pathogenesis and treatment of portal hypertension. HEPATOLOGY 1990; 11:1066-1078.
    • (1990) Hepatology , vol.11 , pp. 1066-1078
    • Reichen, J.1
  • 2
    • 0020677377 scopus 로고
    • Hyperdynamic circulation in portal-hypertensive rat model: A primary factor for maintenance of chronic portal hypertension
    • Vorobioff J, Bredfedlt JE, Groszmann RJ. Hyperdynamic circulation in portal-hypertensive rat model: a primary factor for maintenance of chronic portal hypertension. Am J Physiol 1983;244:G52-G57.
    • (1983) Am J Physiol , vol.244
    • Vorobioff, J.1    Bredfedlt, J.E.2    Groszmann, R.J.3
  • 4
    • 0024523451 scopus 로고
    • Role of prostacyclin in the splanchnic hyperaemia contributing to portal hypertension
    • Sitzmann JV, Bulkley GB, Mitchell M, Campbell K. Role of prostacyclin in the splanchnic hyperaemia contributing to portal hypertension. Ann Surg 1988;209:322-327.
    • (1988) Ann Surg , vol.209 , pp. 322-327
    • Sitzmann, J.V.1    Bulkley, G.B.2    Mitchell, M.3    Campbell, K.4
  • 5
    • 0024441739 scopus 로고
    • Prostacyclin mediates splanchnic vascular response to norepinephrine in portal hypertension
    • Sitzmann JV, Li SS, Lin PW. Prostacyclin mediates splanchnic vascular response to norepinephrine in portal hypertension. J Surg Res 1989; 47:208-211.
    • (1989) J Surg Res , vol.47 , pp. 208-211
    • Sitzmann, J.V.1    Li, S.S.2    Lin, P.W.3
  • 6
    • 0026325515 scopus 로고
    • Modulation of splanchnic vascular sensitivity to angiotensin II
    • Wu Y, Li SS, Campbell KA, Sitzmann JV. Modulation of splanchnic vascular sensitivity to angiotensin II. Surgery 1991;110:162-168.
    • (1991) Surgery , vol.110 , pp. 162-168
    • Wu, Y.1    Li, S.S.2    Campbell, K.A.3    Sitzmann, J.V.4
  • 7
    • 0026749847 scopus 로고
    • Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats
    • Sieber CC, Groszmann RJ. Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats. Gastroenterology 1992;103:235-239.
    • (1992) Gastroenterology , vol.103 , pp. 235-239
    • Sieber, C.C.1    Groszmann, R.J.2
  • 9
    • 0027371887 scopus 로고
    • Effects of nitric oxide and cyclooxygenase inhibition on splanchnic hemodynamic in portal hypertension
    • Wu Y, Burns RC, Sitzmann JV. Effects of nitric oxide and cyclooxygenase inhibition on splanchnic hemodynamic in portal hypertension. HEPATOLOGY 1993;18:1416-1421.
    • (1993) Hepatology , vol.18 , pp. 1416-1421
    • Wu, Y.1    Burns, R.C.2    Sitzmann, J.V.3
  • 10
    • 0026749847 scopus 로고
    • Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats
    • Sieber CC, Groszmann RJ. Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats. Gastroenterology 1992;103:235-239.
    • (1992) Gastroenterology , vol.103 , pp. 235-239
    • Sieber, C.C.1    Groszmann, R.J.2
  • 11
    • 0026504731 scopus 로고
    • Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic vascular circulation of rats with portal hypertension
    • Pizcueta MP, Pique JM, Bosch, Whittle BJR, Moncada S. Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic vascular circulation of rats with portal hypertension. Br J Pharmacol 1992;105:184-190.
    • (1992) Br J Pharmacol , vol.105 , pp. 184-190
    • Pizcueta, M.P.1    Pique, J.M.2    Bosch3    Whittle, B.J.R.4    Moncada, S.5
  • 15
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 16
    • 0025724919 scopus 로고
    • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
    • Cooke JP, Rossitch E, Andon NA, Loscalzo J, Dzau VJ. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. J Clin Invest 1991;88:1663-1671.
    • (1991) J Clin Invest , vol.88 , pp. 1663-1671
    • Cooke, J.P.1    Rossitch, E.2    Andon, N.A.3    Loscalzo, J.4    Dzau, V.J.5
  • 17
    • 0344217166 scopus 로고    scopus 로고
    • Direct evidence for increased functional activity of eNOS in the superior mesenteric arterial (SMA) beds of portal hypertensive rats
    • Hori N, Groszmann RJ. Direct evidence for increased functional activity of eNOS in the superior mesenteric arterial (SMA) beds of portal hypertensive rats [Abstract]. HEPATOLOGY 1996;24:749A.
    • (1996) Hepatology , vol.24
    • Hori, N.1    Groszmann, R.J.2
  • 18
    • 0021064044 scopus 로고
    • Role of endothelium in responses of vascular smooth muscle
    • Furchgott RF. Role of endothelium in responses of vascular smooth muscle. Circ Res 1983;53:557-573.
    • (1983) Circ Res , vol.53 , pp. 557-573
    • Furchgott, R.F.1
  • 19
    • 0030248313 scopus 로고    scopus 로고
    • Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats
    • Cahill PA, Redmond EM, Hodges R, Zhang SM, Sitzmann JV. Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats. J Hepatol 1996;25:370-378.
    • (1996) J Hepatol , vol.25 , pp. 370-378
    • Cahill, P.A.1    Redmond, E.M.2    Hodges, R.3    Zhang, S.M.4    Sitzmann, J.V.5
  • 21
    • 0028925856 scopus 로고
    • Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hypertensive rats
    • Fernandez M, Pagan JC, Casadevall M, Bernadich C, Piera C, Whittle B, Pique JM, et al. Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hypertensive rats. Gastroenterology 1995;108:1487-1495.
    • (1995) Gastroenterology , vol.108 , pp. 1487-1495
    • Fernandez, M.1    Pagan, J.C.2    Casadevall, M.3    Bernadich, C.4    Piera, C.5    Whittle, B.6    Pique, J.M.7
  • 22
    • 0028841506 scopus 로고
    • Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and the hyperdynamic circulation
    • Laffi G, Foschi M, Masini E, Simoni A, Mugnai L, La Villa G, Barletta G, et al. Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and the hyperdynamic circulation. HEPATOLOGY 1995;22:1666-1673.
    • (1995) Hepatology , vol.22 , pp. 1666-1673
    • Laffi, G.1    Foschi, M.2    Masini, E.3    Simoni, A.4    Mugnai, L.5    La Villa, G.6    Barletta, G.7
  • 24
    • 0026095719 scopus 로고
    • The regulation of adenylyl cyclase by receptor G proteins
    • Levitzki A, Bar-Sinai A. The regulation of adenylyl cyclase by receptor G proteins. Pharmacol Ther 1991;50:271-283.
    • (1991) Pharmacol Ther , vol.50 , pp. 271-283
    • Levitzki, A.1    Bar-Sinai, A.2
  • 25
    • 0025027155 scopus 로고
    • G-proteins and endothelial responses
    • Flavahan NA, Vanhoutte PM. G-proteins and endothelial responses. Blood Vessels 1990;27:218-229.
    • (1990) Blood Vessels , vol.27 , pp. 218-229
    • Flavahan, N.A.1    Vanhoutte, P.M.2
  • 26
    • 0024495576 scopus 로고
    • Pertussis toxin inhibits endothelium-dependent relaxations evoked by certain endothelial activators in porcine coronary arteries
    • Flavahan NA, Shimokawa H, Vanhoutte PM. Pertussis toxin inhibits endothelium-dependent relaxations evoked by certain endothelial activators in porcine coronary arteries. J Physiol 1989;408:549-561.
    • (1989) J Physiol , vol.408 , pp. 549-561
    • Flavahan, N.A.1    Shimokawa, H.2    Vanhoutte, P.M.3
  • 27
    • 0027267272 scopus 로고
    • Shear stress elevated endothelial cGMP, role of potassium channel and G-protein coupling
    • Ohno M, Gibbons GH, Dzau VJ, Cooke JP. Shear stress elevated endothelial cGMP, role of potassium channel and G-protein coupling. Circulation 1994;88:193-197.
    • (1994) Circulation , vol.88 , pp. 193-197
    • Ohno, M.1    Gibbons, G.H.2    Dzau, V.J.3    Cooke, J.P.4
  • 28
    • 0028278046 scopus 로고
    • Altered adenyl cyclase activities and G-protein abnormalities in portal hypertensive rabbits
    • Cahill PA, Wu P, Sitzmann JV. Altered adenyl cyclase activities and G-protein abnormalities in portal hypertensive rabbits. J Clin Invest 1994; 93:2691-2670.
    • (1994) J Clin Invest , vol.93 , pp. 2691-12670
    • Cahill, P.A.1    Wu, P.2    Sitzmann, J.V.3
  • 29
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein dye binding
    • Bradford MM. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein dye binding. Ann Biochem 1976;72:248-254.
    • (1976) Ann Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 30
    • 0028240645 scopus 로고
    • The nitric oxide synthase family of proteins
    • Sessa WC. The nitric oxide synthase family of proteins. J Vasc Res 1994; 31:131-143.
    • (1994) J Vasc Res , vol.31 , pp. 131-143
    • Sessa, W.C.1
  • 31
    • 0027055115 scopus 로고
    • Guanosine 5′-0-(3-thiotriphosphate) causes endothelium dependent, pertussis toxin sensitive relaxations in portal coronary arteries
    • Shibano T, Codina J, Birmbaumer L, Vanhoutte PM. Guanosine 5′-0-(3-thiotriphosphate) causes endothelium dependent, pertussis toxin sensitive relaxations in portal coronary arteries. Biochem Biophys Res Commun 1992;189:324-329.
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 324-329
    • Shibano, T.1    Codina, J.2    Birmbaumer, L.3    Vanhoutte, P.M.4
  • 32
    • 0025035805 scopus 로고
    • Fluoride produces endothelium-dependent relaxation and endothelium-independent contraction in coronary artery
    • Cushing DJ, Sabouni MH, Brown GL, Mastafa JS. Fluoride produces endothelium-dependent relaxation and endothelium-independent contraction in coronary artery. J Pharmacol Exp Ther 1990;254:28-32.
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 28-32
    • Cushing, D.J.1    Sabouni, M.H.2    Brown, G.L.3    Mastafa, J.S.4
  • 35
    • 0024362823 scopus 로고
    • Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. Studied with fluoride
    • Zeng YY, Benishin CG, Pang PKT. Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. Studied with fluoride. J Pharmacol Exp Ther 1989;250:343-351.
    • (1989) J Pharmacol Exp Ther , vol.250 , pp. 343-351
    • Zeng, Y.Y.1    Benishin, C.G.2    Pang, P.K.T.3
  • 36
    • 0027935358 scopus 로고
    • Fluoride activates G protein-dependent and independent pathways in dispersed intestinal smooth muscle cells
    • Murthy KS, Makhlouf GM. Fluoride activates G protein-dependent and independent pathways in dispersed intestinal smooth muscle cells. Biochem Biophys Res Commun 1994;202:1681-1687.
    • (1994) Biochem Biophys Res Commun , vol.202 , pp. 1681-1687
    • Murthy, K.S.1    Makhlouf, G.M.2
  • 37
    • 0028816672 scopus 로고
    • G-protein in rat blood vessels. Assessment of functional involvement
    • Abebe W, Edwards JD, Agrawal DK. G-protein in rat blood vessels. Assessment of functional involvement. Gen Pharmacol 1995;26:75-83.
    • (1995) Gen Pharmacol , vol.26 , pp. 75-83
    • Abebe, W.1    Edwards, J.D.2    Agrawal, D.K.3
  • 38
    • 0029152963 scopus 로고
    • Perfused transcapillary smooth muscle and endothelial cell co-culture - A novel in vitro model
    • Redmond EM, Cahill PA, Sitzmann JV. Perfused transcapillary smooth muscle and endothelial cell co-culture - a novel in vitro model. In Vitro Cell Dev Biol 1995;31:601-609.
    • (1995) In Vitro Cell Dev Biol , vol.31 , pp. 601-609
    • Redmond, E.M.1    Cahill, P.A.2    Sitzmann, J.V.3
  • 39
    • 12644306549 scopus 로고    scopus 로고
    • Shear stress-mediated regulation of G-protein expression in co-cultured vascular smooth muscle cells and endothelial cells
    • Redmond EM, Cahill PA, Sitzmann JV. Shear stress-mediated regulation of G-protein expression in co-cultured vascular smooth muscle cells and endothelial cells [Abstract]. FASEB J 1996;10:1015A.
    • (1996) FASEB J , vol.10
    • Redmond, E.M.1    Cahill, P.A.2    Sitzmann, J.V.3
  • 40
    • 0025793981 scopus 로고
    • Regulation of polyphosphsinositide-specific phospholipase C activated by purified Gq
    • Smrcka AV, Hepler JR, Brown KO, Sternweis PC. Regulation of polyphosphsinositide-specific phospholipase C activated by purified Gq. Science 1991;251:804-807.
    • (1991) Science , vol.251 , pp. 804-807
    • Smrcka, A.V.1    Hepler, J.R.2    Brown, K.O.3    Sternweis, P.C.4
  • 41
    • 0023000296 scopus 로고
    • Bradykinin stimulation of inositol triphosphate production in porcine aortic endothelial cells
    • Lambert TL, Kent RS, Whorton AR. Bradykinin stimulation of inositol triphosphate production in porcine aortic endothelial cells. J Biol Chem 1986;261:15288-15293.
    • (1986) J Biol Chem , vol.261 , pp. 15288-15293
    • Lambert, T.L.1    Kent, R.S.2    Whorton, A.R.3
  • 42
    • 0023426241 scopus 로고
    • Fluoride complexes of aluminum or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTP
    • Bigay J, Deterre P, Pfister C, Chabre M. Fluoride complexes of aluminum or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTP. EMBO J 1987;6:2907-2913.
    • (1987) EMBO J , vol.6 , pp. 2907-2913
    • Bigay, J.1    Deterre, P.2    Pfister, C.3    Chabre, M.4
  • 43
    • 0027099768 scopus 로고
    • Long-term β-adrenoceptor-mediated up-regulation of Gi α proteins, Gi a mRNA levels and pertussis toxin-sensitive guanine nucleotide-binding proteins in rat heart
    • Eschenahagen T, Mende U, Diederich M, Nose M, Schmitz W, Scholz H, Esch SC, et al. Long-term β-adrenoceptor-mediated up-regulation of Gi α proteins, Gi a mRNA levels and pertussis toxin-sensitive guanine nucleotide-binding proteins in rat heart. Mol Pharmacol 1992;42:773-783.
    • (1992) Mol Pharmacol , vol.42 , pp. 773-783
    • Eschenahagen, T.1    Mende, U.2    Diederich, M.3    Nose, M.4    Schmitz, W.5    Scholz, H.6    Esch, S.C.7
  • 44
    • 0026764603 scopus 로고
    • Flow-induced prostacyclin production is mediated by a pertussis-toxin sensitive G-protein
    • Berthiaume F, JA Frangos. Flow-induced prostacyclin production is mediated by a pertussis-toxin sensitive G-protein. FEBS Lett 1992;308: 277-279.
    • (1992) FEBS Lett , vol.308 , pp. 277-279
    • Berthiaume, F.1    Frangos, J.A.2
  • 45
    • 0029072762 scopus 로고
    • Flow mediated endothelial mechanotransduction
    • Davies P. Flow mediated endothelial mechanotransduction. Physiol Rev 1995;75:519-560.
    • (1995) Physiol Rev , vol.75 , pp. 519-560
    • Davies, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.