Long-term clarithromycin treatment for cancer cachexia of inoperable non-small cell lung cancer patients

Japanese Journal of Chemotherapy

Volumn 44, Issue 12, 1996, Pages 879-882

  Sakamoto, Masahiro ^a   Mikasa, Keiichi ^a   Hamada, Kaoru ^a   Teramoto, Shoji ^a   Konishi, Mitsuru ^a   Maeda, Koichi ^a   Tsujimoto, Masayuki ^a   Hirai, Tayoko ^a   Mori, Kei ^a   Ueda, Katsuhiro ^a   Sawaki, Masayoshi ^a   Kita, Eiji ^a   Narita, Nobuhiro ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

IL 6; TNF

Indexed keywords

ALBUMIN; CHOLINESTERASE; CLARITHROMYCIN; HEMOGLOBIN; INTERLEUKIN 6; PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BODY WEIGHT; CACHEXIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LOWER RESPIRATORY TRACT INFECTION; LUNG NON SMALL CELL CANCER; MALE;

EID: 12644271195     PISSN: 13407007     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Langstein H N, et al: The roles of γ-Interferon and TNF-α in an experimental rat model of cancer cachexia. Cancer Res. 51: 2302-2306, 1991
2. Brouckaert P, et al: Cercurating interleukin 6 during a continuous infusion of tumor necrosis factor and interferon γ. J. Exp. Med. 169: 2257-2262, 1989
3. Moldawer L L, Georgieff M, Lundholm K: Interleukin 1, tumor necrosis factor alpha (cachectin) and the pathegenesis of cancer cachexia. Clin. Physiol. 263-274, 1987
4. Gelin J, et al. : Role of endogenous tumor necrosis factor a and interleukin 1 for experimental tumor growth and the development of cancer cachexia. Cancer Res. 51: 415-421, 1991
5. Hamaka K, et al. : Antitumor effect of erythromycin in mice. Chemotherapy 41: 59-69, 1995
6. Kawakami J, Cerami A: Studies of endotoxin-indued decrease in lipoprotein lipase activity. J. Exp. Med. 154: 631-639, 1981
7. Beutler B, et al: Identity of tumor necrosis factor and the macrophage-secreted factor, cachectin. Nature 316: 552-554, 1985
8. Tracy K J, et al: Cachectin/TNF induces cachexia, anemia and. inflammation. J. Exp. Med. 167: 1211-1227, 1988
9. Strassman G, et al: Evidence for the involvement of interleukin 6 in experrimental cancer cachexia. J. Clin. Invest. 89: 1681-1684, 1992
10. Strassman G, et al: Mechanism of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia. J. Immunol. 148: 3674-3678, 1992
11. Yanagawa H, et al: Serum levels of interleukin 6 in patients with lung cancer. Br. J. Cancer 71: 1095-1098, 1995
12. Lundholm K, et al: Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors. Cancer Res. 54: 5602-5606, 1995