메뉴 건너뛰기




Volumn 2, Issue 12, 1996, Pages 1943-1949

Irinotecan (CPT-11) metabolites in human bile and urine

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; DRUG METABOLITE; IRINOTECAN;

EID: 12644265333     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (55)

References (14)
  • 2
    • 0028267240 scopus 로고
    • Camptothecins from bench research to hospital wards
    • Potmesil, M. Camptothecins from bench research to hospital wards. Cancer Res., 54: 1431-1439, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 1431-1439
    • Potmesil, M.1
  • 3
    • 0025272187 scopus 로고
    • Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse
    • Kaneda, N., Nagato, H., Furuta, T., and Yokokura T. Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res., 50: 1715-1720, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 1715-1720
    • Kaneda, N.1    Nagato, H.2    Furuta, T.3    Yokokura, T.4
  • 4
    • 0025996996 scopus 로고
    • Intracellular roles of SN-38, an active metabolite of the camptothecin derivative CPT-11, in the anti-tumor effect of CPT-11
    • Kawato, Y., Aonuma, M. Hirota, Y, Kuga, H., and Sato, K. Intracellular roles of SN-38, an active metabolite of the camptothecin derivative CPT-11, in the anti-tumor effect of CPT-11. Cancer Res., 51: 4187-4191, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 4187-4191
    • Kawato, Y.1    Aonuma, M.2    Hirota, Y.3    Kuga, H.4    Sato, K.5
  • 6
    • 0025342506 scopus 로고
    • Nonlinear pharmacokinetics of CPT-11 in rats
    • Kaneda, N., and Yokokura T. Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res., 50: 1721-1725, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 1721-1725
    • Kaneda, N.1    Yokokura, T.2
  • 7
    • 0025858296 scopus 로고
    • Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion
    • Atsumi, R., Suzuki, W., and Hakusui, H. Identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion. Xenobiotica. 21: 1159-1169, 1991.
    • (1991) Xenobiotica , vol.21 , pp. 1159-1169
    • Atsumi, R.1    Suzuki, W.2    Hakusui, H.3
  • 9
    • 0028989171 scopus 로고
    • Identification and kinetics of a β-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan
    • Rivory, L. P., and Robert, J. Identification and kinetics of a β-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan. Cancer Chemother. Pharmacol., 36: 176-179, 1995.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 176-179
    • Rivory, L.P.1    Robert, J.2
  • 10
    • 0028022585 scopus 로고
    • Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
    • Gupia, E., Lestingi, T. M., Mick, R., Ramirez, J., Vokes, E. E., and Ratain, M. J. Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea. Cancer Res., 54: 3723-3725, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3723-3725
    • Gupia, E.1    Lestingi, T.M.2    Mick, R.3    Ramirez, J.4    Vokes, E.E.5    Ratain, M.J.6
  • 11
    • 0026538734 scopus 로고
    • Simultaneous determination of the camptothecin analogue CPT-11 and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in cancer patients
    • Barilero, I., Gandia, D., Armand, J-P., Mathieu-Boué, A , Re, M., Gouyette, A., and Chabot, G. G. Simultaneous determination of the camptothecin analogue CPT-11 and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in cancer patients. J. Chromatogr., 575: 275-280, 1992.
    • (1992) J. Chromatogr. , vol.575 , pp. 275-280
    • Barilero, I.1    Gandia, D.2    Armand, J.-P.3    Mathieu-Boué, A.4    Re, M.5    Gouyette, A.6    Chabot, G.G.7
  • 12
    • 0025899971 scopus 로고
    • Application of chemical cytochrome P-450 systems to studies on drug metabolism. IV. Mechanism of piperidine metabolism pathways via an iminium intermediate
    • Masumoto, H., Ohta, S., and Hirobe, M. Application of chemical cytochrome P-450 systems to studies on drug metabolism. IV. Mechanism of piperidine metabolism pathways via an iminium intermediate. Drug Metab. Dispos., 19: 768-780, 1991.
    • (1991) Drug Metab. Dispos. , vol.19 , pp. 768-780
    • Masumoto, H.1    Ohta, S.2    Hirobe, M.3
  • 14
    • 0027281427 scopus 로고
    • Inhibitory activity of camptothecin derivatives against acetylcholinesterase in dogs and their binding activity to acetylcholine receptors in rats
    • Kawato, Y., Sekiguchi, M., Akahane, K., Tsutomi, Y., Hirota, Y., Kuga, H., Suzuki, W., Hakusui, H., and Sato, K. Inhibitory activity of camptothecin derivatives against acetylcholinesterase in dogs and their binding activity to acetylcholine receptors in rats. J. Pharm. Pharmacol., 45: 444-448, 1993
    • (1993) J. Pharm. Pharmacol. , vol.45 , pp. 444-448
    • Kawato, Y.1    Sekiguchi, M.2    Akahane, K.3    Tsutomi, Y.4    Hirota, Y.5    Kuga, H.6    Suzuki, W.7    Hakusui, H.8    Sato, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.