Ulcerative colitis with overexpression of p53 preceding overt histological abnormalities of the epithelium

Journal of Gastroenterology

Volumn 31, Issue 6, 1996, Pages 860-867

  Matsuda, Keiji ^a   Watanabe, Hidenobu ^a   Ajioka, Yoichi ^a   Kobayashi, Masaaki ^a   Saito, Hidetoshi ^a   Sasaki, Masataka ^a   Yasuda, Kazuhiro ^a   Kuwabara, Akifumi ^a   Nishikura, Ken ^a   Muto, Tetsuichiro ^b  

^a NIIGATA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Carcinogenesis; Cytological atypia; Dysplasia; Immunohistochemistry; Overexpression of p53 protein morphometric analysis; Ulcerative colitis

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ADULT; ADVENTITIA; ARTICLE; CASE REPORT; COLORECTAL CANCER; DYSPLASIA; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM; INTESTINE MUCOSA; INVASIVE CARCINOMA; MALE; MORPHOMETRICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM RESECTION; RECTUM TUMOR; SIGMOIDECTOMY; ULCERATIVE COLITIS;

ADENOCARCINOMA; CELL DIVISION; COLITIS, ULCERATIVE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; MIDDLE AGED; RECTAL NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 12644259498     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02358616     Document Type: Article

References (41)

1. Goldgraber MB, Kirsner JB Carcinoma of the colon in ulcerative colitis. Cancer 1964;17:657-665.
2. Katza I, Brady RS, Morris E, et al. Assessment of colorectal cancer risk in patients with ulcerative colitis: Experience from a private practice. Gastroenterology 1983;85:22-29.
3. Riddell RH, Goldman H, Ransohoff DF, et al. Dysplasia in inflammatory bowel disease: Standardised classification with provisional clinical applications. Hum Pathol 1983;14:931-968.
4. Derroede GJ, Taylor WF, Sauer WG. Cancer risk and life expectancy of children with ulcerative colitis. N Engl J Med 1971;285:17-21.
5. Morson BC, Pang SC. Rectal biopsy as an aid to cancer control in ulcerative colitis. Gut 1962;8:423-434.
6. Fuson JA, Farmer RG, Hawk WA, et al. Endoscopic surveillance for cancer in chronic ulcerative colitis. Am J Gastroenterol 1980;73:120-126.
7. Hulten L, Kewenter J, Ahren C. Precancer and carcinoma in chronic ulcerative colitis: A histopathological and clinical investigation. Scand J Gastroenterol 1972;7:663-669.
8. Cook MG, Goligher JC. Carcinoma and epithelial dysplasia complicating ulcerative colitis. Gastroenterology 1975;68:1127-1136.
9. Fenoglio CM, Pascal RR. Adenomatous epithelium, intraepithelial anaplasia, and invasive carcinoma in ulcerative colitis. Am J Dig Dis 1973;18:558-562.
10. Gewertz BL, Dent TL, Appelman HD. Implications of precancerous rectal biopsy in patients with inflammatory bowel disease. Arch Surg 1976;111:326-329.
11. Nugent FW, Haggitt RC, Colcher H, et al. Malignant potential of chronic ulcerative colitis: Preliminary report Gastroenterology 1979;76:1-5.
12. Yardley JH, Keren DF. "Precancer" lesions m ulcerative colitis: A retrospective study of rectal biopsy and colectomy specimens. Cancer 1974;34:835-844.
13. Lennard-Jones JE, Morson BC, Ritchie JK, et al. Cancer in colitis: Assessment of the individual risk by clinical and histological criteria. Gastroenterology 1977;73:1280-1289.
14. Blackstone MO, Riddell RH, Rogers BHG, et al. Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: An indication for colectomy. Gastroenterology 1981;80:366-374.
15. Dobbins WO III Current status of the precancer lesion in ulcerative colitis. Gastroenterology 1977;73:1431-1433.
16. Myrvold HE, Kock NG, Ahren C. Rectal biopsy and precancer in ulcerative colitis. Gut 1974;15:301-304.
17. Watanabe H, Ajioka Y, Kobayashi M, et al. Early colorectal cancer and molecular biology (in Japanese). I to Cho (Stomach Intestine) 1994;29:171-180.
18. Nishikura K, Watanabe H, Kato N. Gatric microcarcinoma: Its histoligical varieties and differential diagnosis (in Japanese). I to cho (Stomach and Intestine) 1995;30:1295-1307.
19. Oohashi Y, Watanabe H, Ajioka Y, et al. p53 Immunostaining distinguishes malignant from benign lesions of the gallbladder. Pathol Int 1995;45:58-65.
20. Matsuda K, Watanabe H, Ajioka Y, et al. Ulcerative colitis and colon cancer (in Japanese). Mol Med 1995;32:1158-1168.
21. Matsuda K, watanabe H, Jass JR, et al. Incidence of p53-positive cells is different among histological phases of ulcerative colitis. Acta Med Biol 1995;43:197-203.
22. Kobayashi M, Watanabe H, Ajioka Y, et al. Correlation of p53 protein expression with apoptotic incidence in colorectal neoplasia. Virchows Arch [A] 1995;427:27-32.
23. Kobayashi M, Watanabe H, Ajioka Y, et al. Effect of K-ras mutation on morphogenesis of colorectal adenomas and early cancers; relationship to distribution of proliferating cells Hum Pathol (in press).
24. Watanabe H, Ajioka Y, Yamaguchi M, et al New histological criteria of colorectal adenoma and carcinoma (in Japanese). I to Cho (Stomach and Intestine) 1989;24:253-259.
25. Katagiri K, Watanabe H, Ajioka Y, et al. Importance of grading of cytologic atypia for well differentiated adenocarcinoma of the colorectum (in Japanese). I to Cho (Stomach and Intestine) 1994;29:841-849.
26. Ajioka Y, Watanabe H, Kobayashi M, et al. Ulcerative colitis-associated dysplasia and carcinoma. With special reference to their macroscopic and stereomicroscopic characteristics and histological diagnosis (in Japanese). I to Cho (Stomach and Intestine) 1995;30:629-642.
27. Japanese Research Society for Cancer of the Colon and Rectum. General rules for clinical and pathological studies on cancer of the colon, rectum and anus. Jpn J Surg 1983;13:557-573.
28. Watanabe H, Jass JR, Sobin LH. Histological typing of oesophageal and gastric tumours 2nd ed. New York Berlin Heidelberg Tokyo: Springer, 1990:23.
29. Lewin KJ, Riddell RH, Weinstein WM. Gastrointestinal pathology and its clinical implications, vol 2. New York: Igaku-Shoin, 1992:929-949.
30. Pascal RR. Consistency in the terminology of colorectal dysplasia. Hum Pathol 1988;19:1249-1250.
31. Pascal RR. Dysplasia and early carcinoma in inflammatory bowel disease and colorectal adenomas. Hum Pathol 1994;25:1160-1171.
32. Matsuda K, Watanabe H, Ajioka Y, et al. Diagnosis and treatment of colorectal microcarcinoma measuring 5mm or less (in Japanese). I to Cho (Stomach and Intestine) 1995;30:1551-1564.
33. Campo E, Calle-Martin O, Miquel R, et al. Loss of heterozygosity of p53 gene and p53 protein in human colorectal carcinomas. Cancer Res 1991;51:4436-4442.
34. Rodrigues NR, Rowan A, Smith MEF, et al. p53 Mutations in colorectal cancer. Proc Natl Acad Sci USA 1990;87:7555-7559.
35. Purdie CA, O'Grady J, Piris J, et al. p53 expression in colorectal tumors. Am J Pathol 1991;138:807-813.
36. Iggo R, Gatter K, Bartek J, et al. Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet 1990; 335:675-679.
37. Baas IO, Mulder JWR, Offerhaus GJA, et al. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994;172:5-12.
38. Taylor HW, Boyle M, Smith SC, et al. Expression of p53 in colorectal cancer and dysplasia complicating ulcerative colitis. Br J Surg 1993;80:442-444.
39. Chaubert P, Benhatttar J, Saraga E, Costa J. K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis. Am J Pathol 1994;144:767-775.
40. Bernstein CN, Shanahan F, Weinstein WM. Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis? Lancet 1994;343:71-74.
41. Connell WR, Lennard-Jones JE, Williams CB, et al. Factors affecting the outcome of endoscopic surveillance for cancer in ulcerative colitis. Gastroenterology 1994;107:934-944.