Ultrapure dialysis fluid - Direct and indirect benefits in dialysis therapy

Blood Purification

Volumn 22, Issue SUPPL. 2, 2004, Pages 20-25

  Ledebo, Ingrid ^a  

^a Gambro AB   (Sweden)

Author keywords

Dialysis fluid; Fluid quality in dialysis; On line preparation; Sterile fluid; Ultrafilter; Ultrapure dialysis fluid

Indexed keywords

DIALYSIS FLUID; ENDOTOXIN;

BACTERIUM CONTAMINATION; CONFERENCE PAPER; CORRELATION ANALYSIS; HEMODIALYSIS; HEMODYNAMICS; HEMOFILTRATION; HUMAN; INFLAMMATION; INFUSION; PRIORITY JOURNAL; PURIFICATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SOLUTE; ULTRAFILTRATION;

BACTERIA; DIALYSIS SOLUTIONS; ENDOTOXINS; HUMANS; QUALITY CONTROL; RENAL DIALYSIS; STERILIZATION; ULTRAFILTRATION;

EID: 12544259911     PISSN: 02535068     EISSN: None     Source Type: Journal    
DOI: 10.1159/000081869     Document Type: Conference Paper

References (44)

1. Ward RA: Ultrapure dialysate: A desirable and achievable goal for routine hemodialysis. Semin Dial 2000;13:378-380.
2. Ledebo I, Nystrand R: Defining the microbiological quality of dialysis fluid. Artif Organs 1999;23:37-43.
3. Canaud B, Bosc JY, Leray H, Morena M, Stec F: Microbiologic purity of dialysate: Rationale and technical aspects. Blood Purif 2000;18:200-213.
4. European Best Practice Guidelines for Haemodialysis (Part 1), Section IV. Dialysis fluid purity. Nephrol Dial Transplant 2002;17(suppl 7):46-62.
5. Ledebo I: On-line hemodiafiltration: Technique and therapy. Adv Renal Replace Ther 1999;6:195-208.
6. Ledebo I: On-line preparation of solutions for dialysis: Practical aspects versus safety and regulations. J Am Soc Nephrol 2002;13:S78-S83.
7. Nystrand R: Standards and standardisation of detection methods for bacteria and endotoxin in water and dialysis fluid. Nieren Hochdruckkrankh 1999;2:43-48.
8. Pass T, Wright R, Sharp B, Harding GB: Culture of dialysis fluids on nutrient-rich media for short periods at elevated temperatures underestimate microbiological contamination. Blood Purif 1996;14:136-145.
9. Cappelli G, Ballestri M, Perrone S, Ciuffreda A, Inguaggiato P, Albertazzi A: Biofilms invade nephrology: Effects in hemodialysis. Blood Purif 2000;18:224-230.
10. Oie S, Kamiya A, Yoneda I, Uchiyama K, Tsuchida M, Takai K, Naito K: Microbial contamination of dialysate and its prevention in haemodialysis units. J Hosp Infect 2003;54:115-119.
11. Tokars JI, Alter MJ, Favero MS, Moyer LA, Miller E, Bland LA: National surveillance of dialysis associated diseases in the United States 1992. ASAIO J 1994;40:1020-1031.
12. Gordon SM, Oettinger CW, Bland LA, Oliver JC, Arduino MJ, Aguero SM, McAllister SK, Favero MS, Jarvis WR: Pyrogenic reactions in patients receiving conventional, high-efficiency, or high-flux hemodialysis treatments with bicarbonate dialysate containing high concentrations of bacteria and endotoxin. J Am Soc Nephrol 1992;2:1436-1444.
13. Pegues DA, Oettinger CW, Bland LA, Oliver JC, Arduino MJ, Aguero SM, McAllister SK, Gordon SM, Favero MS, Jarvis WR: A prospective study of pyrogenic reactions in hemodialysis patients using bicarbonate dialysis fluids filtered to remove bacteria and endotoxin. J Am Soc Nephrol 1999;3:1002-1007.
14. Lonnemann G: The quality of dialysate: An integrated approach. Kidney Int Suppl 2000;76:112-119.
15. Ward RA: Microbiological quality requirements for dialysate: Is it time for a change? - Yes. Nephrol News Issues 2002;11:26, 28-29, 33-34, 36, 38, 40, 73.
16. Schindler R, Lonnemann G, Schäffer J, Shaldon S, Koch KM, Krautzig S: The effect of ultrafiltered dialysate on the cellular content of interleukin-1 receptor antagonist in patients on chronic hemodialysis. Nephron 1994;68:229-233.
17. Pertosa G, Gesualdo L, Bottalico D, Schena FP: Endotoxins modulate chronically tumour necrosis factor-α and interleukin-6 release by uraemic monocytes. Nephrol Dial Transplant 1995;10:328-333.
18. Schindler R, Christ-Kohlrausch F, Frei U, Shaldon S: Differences in the permeability of high-flux dialyzer membranes for bacterial pyrogens. Clin Nephrol 2003;59:447-454.
19. Nubé MJ, Grooteman MPC: Impact of contaminated dialysate on long-term haemodialysis-related complications: Is it really that important? Nephrol Dial Transplant 2001;16:1986-1991.
20. Baz M, Durand C, Ragon A, Jaber K, Andrieu D, Merzouk T, Purgus R, Olmer M, Reynier JP, Berland Y: Using ultrapure water in hemodialysis delays carpal tunnel syndrome. Int J Artif Organs 1991;14:681-685.
21. Quellhorst E: Hämodialyseverfahren. Nieren Hochdruckkrankh 1998;27:S35-S41.
22. Sitter T, Bergner A, Schiffl H: Dialysate-related cytokine induction and response to recombinant human erythropoietin in haemodialysis patients. Nephrol Dial Transplant 2000;15:1207-1211.
23. Matsuhashi N, Yoshioka T: Endotoxin-free dialysate improves response to erythropoietin in hemodialysis patients. Nephron 2002;92:601-604.
24. Schiffl H, Lang SM, Stratakis D, Fischer R: Effects of ultrapure dialysis fluid on nutritional status and inflammatory parameters. Nephrol Dial Transplant 2001;16:1863-1869.
25. Kleophas W, Haastert B, Backus G, Hilgers P, Westhoff A, van Endert G: Long-term experience with an ultrapure individual dialysis fluid with a batch-type machine. Nephrol Dial Transplant 1998;13:3118-3125.
26. Lonnemann G: Chronic inflammation in hemodialysis: The role of contaminated dialysate. Blood Purif 2000;18:214-223.
27. Nakatani T, Tsuchida K, Sugimura K, Yoshimura R, Takemoto Y: Investigation of endotoxin adsorption with polyether polymer alloy dialysis membranes. Int J Mol Med 2003;11:195-197.
28. Vanholder R, Van Haecke E, Veys N, Ringoir S: Endotoxin transfer through dialysis membranes: Small- versus large-pore membranes. Nephrol Dial Transplant 1992;7:333-339.
29. Panichi V, Tetta C, Rindi P, Palla R, Lonnemann G: Plasma C-reactive protein is linked to backfiltration associated interleukin-6 production. ASAIO J 1998;44:M415-M417.
30. Maduell F, Navarro V, Cruz MC, Torregrosa E, Garcia D, Simon V, Ferrero JA: Osteocalcin and myoglobin removal in on-line hemodiafiltration versus low- and high-flux hemodialysis. Am J Kidney Dis 2002;40:582-589.
31. Dellanna F, Wuepper A, Baldamus CA: Internal filtration - Advantage in haemodialysis? Nephrol Dial Transplant 1996;11(suppl 2):83-86.
32. Yamashita AC: New dialysis membrane for removal of middle molecule uremic toxins. Am J Kidney Dis 2001;38(suppl 1):217-219.
33. Locatelli F, Marcelli D, Conte F, Limido A, Malberti F, Spotti D, The Registro Lombardi Dialisi e Traplanto: Comparison of mortality in ESRD patients on convective and diffusive extracorporeal treatments. Kidney Int 1999;55:286-293.
34. Nakai S, Iseki K, Tabei K, Kubo K, Masakane I, Fushimi K, Kikuchi K, Shinzato T, Sanaka T, Akiba T: Outcomes of hemodiafiltration based on Japanese dialysis patients registry. Am J Kidney Dis 2001;38(suppl 1):212-216.
35. Cheung AK, Levin NW, Greene T, Agodoa L, Bailey J, Beck G, Clark W, Levey AS, Leypoldt JK, Ornt DB, Rocco MV, Schulman G, Schwab S, Teehan B, Eknoyan G for the HEMO Study Group: Effects of high-flux hemodialysis on clinical outcomes: Results of the HEMO Study. J Am Soc Nephrol 2003;14:3251-3263.
36. Altieri P, Sorba G, Bolasco P, Asproni E, Ledebo I, Cossu M, Ferrara R, Ganadu M, Cadinu F, Serra G, Cabiddu G, Sau G, Casu D, Passaghe M, Bolasco F, Pistis R, Ghisu T: Predilution haemofiltration - the Second Sardinian Multicentre Study: Comparisons between haemofiltration and haemodialysis during identical Kt/V and session times in a long-term crossover study. Nephrol Dial Transplant 2001;16:1207-1213.
37. Lin CL, Huang CC, Chang CT, Wu MS, Hung CC, Chien CC, Yang CW: Clinical improvement by increased frequency of on-line hemodiafiltration. Renal Failure 2001;23:193-206.
38. Henderson LW: Hemodynamic instability during different forms of dialysis therapy: Do we really know why? Blood Purif 1996;14:395-404.
39. Henderson LW, Koch KM, Dinarello CA, Shaldon S: Hemodialysis hypotension: The interleukin hypothesis. Blood Purif 1983;1:3-8.
40. Beerenhout CH, Kooman JP, Luik AJ, Jeuken-Mertens SGJ, van der Sande FM, Leunissen KML: Optimizing renal replacement therapies - A case for on-line filtration therapies? Nephrol Dial Transplant 2002;17:2065-2070.
41. Guth HJ, Gruska S, Kraatz G: On-line production of ultrapure substitution fluid reduces TNF-α and IL-6 release in patients on hemodiafiltration therapy. Int J Artif Organs 2003;26:181-187.
42. Lin CL, Huang CC, Yu CC, Wu CH, Chang CT, Hsu HH, Hsu PY, Yang CW: Improved iron utilization and reduced erythropoietin resistance by on-line hemodiafiltration. Blood Purif 2002;20:349-356.
43. Bonforte G, Grillo P, Zerbi S, Surian M: Improvement of anemia in hemodialysis patients treated by hemodiafiltration with high-volume on-line-prepared substitution fluid. Blood Purif 2002;20:357-363.
44. Ledebo I: Does convective dialysis therapy applied daily approach renal blood purification? Kidney Int Suppl 2001;78:286-291.