Purification and characterization of NADPH-dependent aldo-keto reductase specific for β-keto esters from Penicillium citrinum, and production of methyl (S)-4-bromo-3-hydroxybutyrate

Applied Microbiology and Biotechnology

Volumn 66, Issue 1, 2004, Pages 53-62

  Itoh, N ^a   Asako, H ^b   Banno, K ^a   Makino, Y ^a   Shinohara, M ^a   Dairi, T ^a   Wakita, R ^b   Shimizu, M ^b  

^a TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^b SUMITOMO CHEMICAL CO LTD   (Japan)

Author keywords

Keto ester; Aldo keto reductase (NADPH); Biocatalyst; Methyl (S) 4 bromo 3 hydroxybutyrate; Penicillium citrinum

Indexed keywords

CATALYSIS; CLONING; DEHYDROGENATION; ESCHERICHIA COLI; ESTERS; GENES; PURIFICATION;

ENANTIOMERS; KETO DERIVATIVES; MOLECULAR MASS; TWO-PHASE SYSTEMS;

ENZYMES;

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ALDEHYDE KETONE REDUCTASE; BUTYRIC ACID DERIVATIVE; ENZYME; GLUCOSE DEHYDROGENASE; METHYL 4 BROMO 3 HYDROXYBUTYRATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; WATER;

METABOLISM;

ARTICLE; BIOCATALYST; BIOTECHNOLOGY; CATALYSIS; CHEMICAL REACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEHYDROGENATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIUM CITRINUM; REACTION ANALYSIS; STEREOSPECIFICITY;

ALCOHOL OXIDOREDUCTASES; BACILLUS; ESCHERICHIA COLI; ESTERS; GLUCOSE 1-DEHYDROGENASE; HYDROGEN-ION CONCENTRATION; HYDROXYBUTYRATES; KETONES; ORGANISMS, GENETICALLY MODIFIED; PENICILLIUM; RECOMBINANT PROTEINS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; PENICILLIUM; PENICILLIUM CITRINUM;

EID: 12544250501     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-004-1702-7     Document Type: Article

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