Renal transplant recipients over aged 60 have diminished immune activity and a low risk of rejection

International Urology and Nephrology

Volumn 36, Issue 3, 2004, Pages 451-456

  Friedman, Amy L ^a   Goker, Onur ^a   Kalish, Meredith A ^a   Basadonna, Giacomo P ^a   Kliger, Alan S ^a   Bia, Margaret J ^a   Lorber, Marc I ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Age; Geriatric; Immunosuppression; Kidney transplant; Rejection

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; LYMPHOCYTE ANTIBODY; METHYLPREDNISOLONE; OKT 3; STEROID;

ACUTE GRAFT REJECTION; ADOLESCENT; ADULT; AGED; AGING; ARTICLE; CADAVER KIDNEY; CHILD; CLINICAL PROTOCOL; CONTROLLED STUDY; GERIATRIC CARE; GRAFT REJECTION; HUMAN; IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY BIOPSY; KIDNEY TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; OUTCOMES RESEARCH; QUANTITATIVE ANALYSIS; RECIPIENT; RISK ASSESSMENT; SURVIVAL RATE; UNITED STATES;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CHILD; CHILD, PRESCHOOL; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSION; KIDNEY TRANSPLANTATION; MIDDLE AGED; RISK FACTORS;

EID: 12444346875     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11255-004-8685-2     Document Type: Article

References (15)

1. RJ Wood MJ Jurkiewica 1994 Plastic and reconstructive surgery In: Si Schwartz GT Shires FC Spencer (eds.) Principles of Surgery 6 McGraw-Hill, Inc. New York
2. CB Mendoza Jr RW Postlethwait WD Johnson 1970 Incidence of wound disruption following operation. Arch Surg 101 396-398
3. F Yao S Visovatti CS Johnson et al. 2001 Age and growth factors in porcine full-thickness wound healing Wound Repair Reg 9(5) 371
4. DR Thomas 2001 Age-related changes in wound healing Drugs Aging 18(8) 607
5. MJ Bia 1999 Geriatric issues in renal transplantation. Geriatric Neph Urol 9 109-113
6. 2000 Annual report of the U.S. scientific registry of transplant recipients and the Organ Procurement and Transplantation Network: transplant data 1989-1998.
7. U.S. Renal Data System, USRDS 2001 annual data report: Atlas of end-stage renal disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2001.
8. CA Vivas DP Hickey ML Jordan et al. 1992 Renal transplantation in patients 65 years old or older J Urol 147(4) 990
9. BD Kahan SM Stepkowski KL Napoli 2001 The development of Sirolimus: The University of Texas-Houston experience. In: JM Cecka PI Terasaki eds., Clinical Transplants 2000 UCLA Immunogenetics Center Los Angeles
10. A Moss JS Najarian DER Sutherland et al. 2001 5,000 kidney transplants - A single-center experience. In: JM Cecka PI Terasaki eds., Clinical transplants 2000 UCLA Immunogenetics Center Los Angeles
11. KJ Rodysill L Hansen JJ O'Leary 1989 Cutaneous-delayed hypersensitivity in nursing home and geriatric clinic patients: Implications for the tuberculin test J Am Geriatr Soc 37 435
12. JE McElhaney GS Meneilly BL Beattie et al. 1992 The effect of influenza vaccination on IL-1 production in healthy elderly - Implications for current vaccination practices J Gerontol 47 M3
13. R Aspinall 2000 Longevity and the immune response Biogerontology 1 273
14. S Rajagopalan TT Yoshikawa 2000 Tuberculosis in the elderly Z Gerontol Geriatr 33 374
15. RA Wolfe VB Ashby EL Milford et al. 1999 Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Eng J Med 341(23) 1725-1730