Influence of various antimicrobial agents on the intestinal flora in an intestinal MRSA-carrying rat model

Journal of Infection and Chemotherapy

Volumn 10, Issue 6, 2004, Pages 338-342

  Takahata, Masahiro ^a   Sugiura, Yoko ^a   Ameyama, Satoshi ^a   Yotsuji, Akira ^b   Mitsuyama, Junichi ^a   Sumiyama, Yoshinobu ^c   Kusachi, Shinya ^c  

^a TOYAMA CHEMICAL CO LTD   (Japan)

^b Taisho Toyama Pharmaceutical Co Ltd   (Japan)

^c TOHO UNIVERSITY   (Japan)

Author keywords

Animal model; Intestinal flora; MRSA

Indexed keywords

ANTIINFECTIVE AGENT; CEFAZOLIN; CEFMETAZOLE; CYCLOPHOSPHAMIDE; FLOMOXEF; KANAMYCIN; METRONIDAZOLE; OXACILLIN; PIPERACILLIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL CELL; BACTERIAL COUNT; BACTEROIDES; COMPARATIVE STUDY; CONTROLLED STUDY; CONVALESCENCE; ESCHERICHIA COLI; INTESTINE FLORA; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; RAT; STATISTICAL SIGNIFICANCE;

EID: 12444337500     PISSN: 1341321X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10156-004-0346-y     Document Type: Article

References (16)

1. Sumiyama Y, Arima Y. The infectious disease in perioperative period of gastroenterological surgery. Clin Microbiol 1999;26:63-9.
2. Kobayashi Y, Taniguchi K, Uehata K, Hotsuta K, Sahara M, Naka T, et al. The principle of prevention for postoperative infection. Jpn J Med Pharm Sci 2002;47:11-9.
3. Aoyagi K. Experimental studies on the selection of antibacterial agents for the prevention of postoperative infection following colon surgery by using rats. J Jpn Soc Colo-protol 1995;48:979-91.
4. Sumiyama Y. Importance of intestinal flora on digestive tract surgical infection. Jpn J Gastroenterol Surg 1997;30:121-5.
5. Japanese Society of Chemotherapy. Method for the determination of minimum inhibitory concentration (MIC) of aerobic bacteria by agar dilution method. Chemotherapy (Tokyo) 1981;29:76-9.
6. Japanese Society of Chemotherapy. Method for the determination of minimum inhibitory concentration (MIC) of anaerobic bacteria by agar dilution method. Chemotherapy (Tokyo) 1979;27:559-60.
7. Sumiyama Y, Kusachi S. Managements of hospital MRSA infections in digestive tract surgery. Nippon Geka Gakkai Zasshi 1992; 93:898-901.
8. Hori K, Yura J, Shinagawa N, Sakurai S, Mashita K, Mizuno A. Postoperative enterocolitis and current status of MRSA enterocolitis - the result of a questionnaire survey in Japan. Kansenshogaku Zasshi 1989;63:701-7.
9. Hanatani Y, Hasumi T, Asagoe T, Miyoshi H, Takami H, Kodaira S. Clinical study on postoperative infections caused by methicillin-resistant Staphylococcus aureus after gastrointestinal surgery. Kansenshogaku Zasshi 1993;67:24-9.
10. Iwai S, Sato T, Kunimatsu M, Tanaka H, Kato K, Akutsu M, et al. Hospital acquired infection in surgical field and its countermeasure present situation of anaerobes, P. aeruginosa and MRSA infection. Nippon Geka Gakkai Zasshi 1992;93:906-9.
11. Iwai S, Akutsu M. Severe infection in gastroenterological field; MRSA (methicillin resistant Staphylococcus aureus) enterocolitis. Nippon Rinsho 1994;52:456-61.
12. Schiller B, Chiorazzi N, Farber BF. Methicillin-resistant staphylococcal enterocolitis. Am J Med 1998;105:164-6.
13. Shimada M, Kamakura T, Itasaka H, Matsumata T, Hashizume M, Sugimachi K. The significance of methicillin-resistant Staphylococcus aureus infection in general surgery: a multivariate analysis of risk factors and preventive approaches. Surg Today 1993;23:880-4.
14. Yoshida Y. Methicillin-resistant Staphylococcus aureus proliferation in the rat gut is influenced by gastric acid inhibition and the administration of antibiotics. Surgery Today 1999;29:327-37.
15. Kusachi S, Sumiyama Y, Nagao J, Kawai K, Arima Y, Yoshida Y, et al. New methods of control against postoperative methicillin-resistant Staphylococcus aureus infection. Surgery Today 1999;29:724-9.
16. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services. Infect Control Hosp Epidemiol 1999;20:250-78.