Hypodermin A, a new inhibitor of human complement for the prevention of xenogeneic hyperacute rejection

Xenotransplantation

Volumn 10, Issue 3, 2003, Pages 267-277

  Malassagne, B ^a,b   Regimbeau, Jean Marc ^a,b,e   Taboit, F ^c   Troalen, F ^d   Chereau C ^a   Moire N ^c   Attal, J ^c   Batteux, F ^a   Conti, F ^a   Calmus, Y ^a   Houssin, D ^b   Boulard, C ^c   Houdebine, L M ^c   Weill, B ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^c CEMAGREF   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e BEAUJON HOSPITAL   (France)

Author keywords

Complement; Endothelial cells; Hypodermin A; Molecular biology; Xenotransplantation

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT INHIBITOR; HYPODERMIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHO CELL; CYTOLYSIS; ENDOTHELIUM CELL; FEMALE; GENETIC TRANSFECTION; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; HYPERACUTE GRAFT REJECTION; MOLECULAR BIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; WESTERN BLOTTING; XENOGRAFT; XENOTRANSPLANTATION;

ACUTE DISEASE; AMINO ACID SEQUENCE; ANIMALS; CELL SURVIVAL; CHO CELLS; COMPLEMENT C3; COMPLEMENT C6; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT MEMBRANE ATTACK COMPLEX; CRICETINAE; ENDOTHELIUM, VASCULAR; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMANS; MOLECULAR SEQUENCE DATA; RATS; SERINE ENDOPEPTIDASES; SWINE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 12444324664     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3089.2003.02030.x     Document Type: Article

References (45)

1. STARZL TE, FUNG J, TZAKIS A et al. Baboon-to-human liver transplantation. Lancet 1993; 341: 65.
2. STARZL TE, TZAKIS A, FUNG JJ, TODO S, DEMETRIS AJ et al. Prospects of clinical xenotransplantation. Transplant Proc 1994; 26: 1082.
3. AUCHINCLOSS H, SACHS DH. Xenogeneic transplantation. Annu Rev Immunol 1998; 16: 433.
4. LOGAN JS. Prospects for xenotransplantation. Curr Opin Immunol 2000; 12: 563.
5. BRADLEY JA. Overcoming the immunological barriers to xenotransplantation. Transplantation 1999; 68: 613.
6. SOIN B, VIAL M, FRIEND PJ. Xenotransplantation. Br J Surg 2000; 87: 138.
7. GEWURZ HD, CLARK DS, COOPER MD, VARCO RL, GOOD RA. Effect of cobra venorn-induced inhibition of complement activity on allograft and xenograft rejection reactions. Transplantation 1967; 5: 1296.
8. CANDINAS D, LESNIKOSKI BA, ROBSON SC et al. Effect of repetitive high-dose treatment with soluble complement receptor type and cobra venom factor on discordant xenograft survival. Transplantation 1996; 62: 336.
9. PRUIT SK, KIRK AD, BOLLINGER RR et al. The effect of soluble complement receptor type Ion hyperacute rejection of porcine xenografts. Transplantation 1994; 57: 363.
10. LANTERI MB, POWELL MS, CHRISTIANSEN D et al. Inhibition of hyperacute transplant rejection by soluble proteins with the functional domains of Cd46 and Fcgamma RII. Transplantation 2000; 69: 1128.
11. BROOIMANS RA, VAN DE ARK AA, TOMITA M, VAN ES LA, DAHA MR. CD59 expressed by human endothelial cells functions as a protective molecule against complement-mediated lysis. Eur J Immunol 1992; 22: 791.
12. DIAMOND LE, MCCURRY KR, MARTIN MJ et al. Characterization of transgenic pigs expressing functionally active human CD59 on cardiac endothelium. Transplantation 1996; 61: 1241.
13. FODOR WL, WILLIAMS WL, MATIS LA et al. Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection. Proc Natl Acad Sci USA 1994; 91: 1153.
14. COZZI E, WHITE D. The generation of transgenic pig as a potential organ donors for humans. Nature Med 1995; 1: 964.
15. BYRNE GW, MCCURRY KR, MARTIN MJ et al. Transgenic pigs expressing human CD59 and decay-accelerating factor produce an intrinsic barrier to complement-mediated damage. Transplantation 1997; 63: 149.
16. BHATTI FN, SCHMOECKLE M, ZAIDI A et al. Three-month survival of HDAF transgenic pig hearts transplanted into primates. Transplant Proc 1999; 31: 958.
17. YEATMAN M, DAGGETT CW, LAU CL et al. Human complement regulatory proteins protect swine lungs from xenogeneic injury. Ann Thorac Surg 1999; 67: 769.
18. COWAN PJ, SHINKEL TA, AMINIAN A et al. High-level co-expression of complement regulators on vascular endothelium in transgenic mice: CD55 and CD59 provide greater protection from human complement-mediated injury than CD59. Xenotransplantation 1998; 5: 184.
19. SCHMOECKEL M, BHATTI FN, ZAIDI A et al. Xenotransplantation of pig organs transgenic for human DAF. an update. Transplant Proc 1997; 29: 3157.
20. SCHMOECKEL M, BHATTI FN, ZAIDI A et al. Orthotopic heart transplantation in a transgenic pig-to-primate model. Transplantation 1998; 65: 1570.
21. COZZI E, TUCKER AW, LANG FORD GA et al. Characterization of pigs transgenic for human decay-accelerating factor. Transplantation 1997; 64: 1383.
22. VAN DEN BERG CW, RIX C, HANNA SM, PEREZ DE LA LASTRA JM, MORGAN BP. Role and regulation of pig CD59 and membrane cofactor protein/CD46 expressed on pig aortic endothelial cells. Transplantation 2000; 70: 667.
23. HAMANN J, VOGEL B, VAN SCHIJNDEL GM, VAN LIER RA. The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF). J Exp Med 1996; 184: 1185.
24. HAHN WC, MENU E, BOTHWELL AL, SIMS PL, BIERER BE. Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59. Science 1992; 256: 1805.
25. NANICHE D, VARIOR-KRISHNAN O, CERVONI F et al. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J Virol 1993; 67: 6025.
26. WARD T, PIPKIN PA, CLARKSON NA et al. Decay-accelerating factor CD55 is identified as the receptor for echovirus 7 using CELICS, a rapid immuno-focal cloning method. EMBO J 1994; 13: 5070.
27. KAMAUCHOW TM, TOISON DL, HARRISON BA et al. The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55). J Virol 1996; 70: 5143.
28. NOWICKI B, HART A, COYNE KE, LUBLIN DM, NOWICKI S. Short consensus repeat-3 domain of recombinant decay-accelerating factor is recognized by Escherichia coli recombinant Dr adhesin in a model of a cell-cell interaction. J Exp Med 1993; 178: 2115.
29. CHABAUDIE N, BOULARD C. Effect of Hypodermin A, an enzyme secreted by Hypoderma lineatum (Insect Oestridae), on the bovine immune system. Vet Immunol Immunopathol 1992; 31: 167.
30. NICOLAS-GAULARD I, MOIRE N, BOULARD C. Effect of the parasite enzyme, hypodermin A, on bovine lymphocyte proliferation and interleukin-2 production via the prostaglandin pathway. Immunology 1995; 85: 160.
31. BOULARD C. Degradation of bovine C3 by serine proteases from parasites Hypoderma lineatum (Diptera, Oestridae). Vet Immunol Immunopathol 1989; 20: 387.
32. REGIMBEAU JM, MALASSAGNE B, TABOIT F et al. A new model of isolated perfused heart. Study of hypodermin A in hyperacute xenograft rejection. Ann Chir 2001; 126: 1007.
33. MALASSAGNE B, TABOIT F, CONTI F et al. A newly established porcine aortic endothelial cell line: characterization and application to the study of human-to-swine graft rejection. Exp Cell Res 1998; 238: 90.
34. TONG NT, IMHO JM, LECROISEY A, KEIL B. Hypodermin A, a trypsin-like neutral proteinase from the insect Hypoderma lineatum. Biochim Biophys Act 1981; 658: 209.
35. LOWRY OH, ROSEBROUGH NJ, FARR L, RANDALL RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265.
36. ZHAO Z, TERMIGNON JL, CARDOSO J et al. Hyperacute xenograft rejection in the swine to human donor recipient combination: in vitro analysis of complement activation. Transplantation 1994; 57: 245.
37. MOSMANN T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays. J Lmmunol 1983; 65: 55.
38. GAMBIEZ L, SALAMÉ E, CHÉREAU C et al. Role of natural IgM in the hyperacute rejection of discordant heart xenografts. Transplantation 1992; 54: 577.
39. ONO K, LINDSEY ES. Improved technique of heart transplantation in rats. J Thor Cardiovas Surg 1969; 549: 225.
40. MERRIfIELD RB. Solid-phase peptide synthesis. Adv Enzymol Relat Areas Mol Biol 1969; 32: 221.
41. SAMBROOK J, FRITSCH EF, MANIATIS T. Plasmid vectors. In: Laboratory Press (ed). Molecular Cloning: a Laboratory Manual, 1: 1. New York: Cold Spring Laboratory Press, 1989.
42. KIM DW, UETSUKI T, KASIRO Y, YAMAGUCHI N, SUGANO S. Use of the human elongation factor la promoter as a versatile and efficient expression system. Gene 1990; 91: 217.
43. MIYAGAWA S, HIROSE H, SHIRAKURA R et al. The mechanism of discordant xenograft rejection. Transplantation 1988; 46: 825.
44. DORLING, A. Graft-specific inhibition of complement activation after xenotransplantation; genetically modified pig organs versus systemic anticomplement strategies. Transplantation 2000; 69: 1033.
45. MIYAGAWA S, SHIRAKURA R, IWATA K et al. Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAF hybrid, on complement-mediated swine endothelial cell lysis. Transplantation 1994; 58: 834.