Drug-induced hypersensitivity syndrome due to anticonvulsants in a two-year-old boy

Journal of Dermatology

Volumn 31, Issue 12, 2004, Pages 1009-1013

  Criado, Paulo Ricardo ^a,d   Criado, Roberta F J ^b   Vasconcellos, Cidia ^c   Pegas, Jose Roberto P ^a   Cera, Patrícia Calil ^a  

^a Hosp Serv Pub Estadual S Paulo   (Brazil)

^b Sevidor Publico Estadual Sao Paulo   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d NONE   (Brazil)

Author keywords

Antiepileptic hypersensitivity syndrome; Drug induced hypersensitivity syndrome (DIHS); Human herpesvirus 6; Phenytoin; Severe cutaneous drug eruptions

Indexed keywords

ANTICONVULSIVE AGENT; METHYLPREDNISOLONE; PHENOBARBITAL; PHENYTOIN; PREDNISONE; VALPROIC ACID;

ARTICLE; CASE REPORT; CAUCASIAN; DISEASE SEVERITY; DRUG ERUPTION; DRUG HYPERSENSITIVITY; DRUG INDUCED DISEASE; DRUG INDUCED HYPERSENSITIVITY SYNDROME; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; MALE; SEIZURE;

EID: 12444311722     PISSN: 03852407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1346-8138.2004.tb00645.x     Document Type: Article

References (19)

1. 2- blockers, IMAJ, 1: 95-97, 1999.
2. Roujeau JC, Stern RS: Severe adverse cutaneous reactions to drugs, N Engl J Med, 331: 1272-1285, 1994.
3. Carrol MC, Yueng-Yue KA, Esterly NB, Drolet BA: Drug-induced hypersensitivity syndrome in pediatrics patients, Pediatrics, 108: 485-492, 2001.
4. Drago F, Rampini P, Rampini E, Rebora A: Atypical exanthems: Morphology and laboratory investigations may lead to an aetiological diagnosis in about 70% of cases, Br J Dermatol, 147: 255-260, 2002.
5. Tohyama M, Yahata Y, Yasukawa M, et al: Severe hypersensitivity syndrome due to sulfalazine associated with reactivation of human herpesvirus 6, Arch Dermatol, 134: 1113-1117, 1998.
6. Suzuki Y, Inagi R, Aono T, Yamanishi K, Shiohara T: Human herpesvirus 6 infection as a risk factor for the development of severe drug induced hypersensitivity syndrome, Arch Dermatol, 134: 1108-1112, 1998.
7. Nagai A, Hattori T, Ishikawa O: A case of hypersensitivity syndrome due to phenitoin. J Dermatol, 29: 670-675, 2002.
8. Kunisaki Y, Goto H, Kitagawa K, Nagano M: Salazosulfapyridine induced hypersensitivity syndrome associated with reactivation of human herpesvirus 6, Intern Med, 42: 203-207, 2003.
9. Descamps V, Valence A, Edlinger C, et al: Association of human herpesvirus 6 infection with drug reaction with eosinophilia and systemic symptoms, Arch Dermatol, 137: 301-304, 2001.
10. Tohyama M, Hashimoto K: Drug hypersensitivity syndrome and human herpesvirus 6 reactivation [letter], Arch Dermatol, 138: 268-269, 2002.
11. Massaki T, Fukunaga A, Toyama M, et al: Human herpesvirus 6 encephalitis in allopurinol-induced hypersensitivity syndrome, Acta Dermatol Venereol, 83: 128-131, 2003.
12. Fujino Y, Nakajima M, Inoue H, et al: Human herpesvirus 6 encephalitis associated with hypersensitivity syndrome, Ann Neurol, 51: 771-774, 2002.
13. Hashimoto K, Yasukawa M, Tohyama M: Human herpesvirus 6 and drug allergy, Curr Opin Allergy Clin Immunol, 3: 255-260, 2003,
14. Kano Y, Inaoka M, Shiohara T: Association between anticonvulsant hypersensitivity syndrome and human herpesvirus 6 reactivation and hipogammaglobulimeia, Arch Dermatol, 140: 183-188, 2004.
15. Ward HA, Russo GG, Shrum J: Cutaneous manifestations of antiretroviral therapy, J Am Acad Dermatol, 46: 284-293, 2002.
16. Bocquet H, Bagot M, Roujeau RC: Drug-induced pseudolymphoma and drug hypersensitivity syndrome (Drug Rash with Eosinophilia and Systemic Symptoms: DRESS), Semin Cut Med Surg, 15: 250-257, 1996.
17. Schlienger RG, Shear NH: Antiepileptic drug hypersensitivity syndrome, Epilepsia, 39: s3-s7, 1998.
18. Verotti A, Trotta D, Salladini C, Chiarelli F: Anti-convulsant Hypersensitivity Syndrome in children: incidence, prevention and management, CNS Drugs, 16: 197-205, 2002.
19. Trent JT, Kirsner RS, Romanelli P, Kerdel FA: Analysis of intravenous immunoglobulin for the treatment of toxic epidermal necrolysis using SCORTEN: The University of Miami Experience, Arch Dermatol, 139: 39-43, 2003.