Collagen/chitosan/heparin complex with improved biocompatibility for hepatic tissue engineering

Journal of Bioactive and Compatible Polymers

Volumn 20, Issue 1, 2005, Pages 15-28

  Yu, Xing ^a   Bichtelen, Alexandra ^a   Wang, Xiaohong ^a   Yan, Yongnian ^a   Lin, Feng ^a   Xiong, Zhuo ^a   Wu, Rendong ^a   Zhang, Renji ^a   Lu, Qingping ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Biocompatibility; Biodegradable; Collagen chitosan heparin complex; Hepatocyte; Scaffold; Tissue engineering

Indexed keywords

BIOCOMPATIBILITY; BIOLOGICAL ORGANS; BIOMEDICAL ENGINEERING; BLOOD; CELL MEMBRANES; CHITIN; COLLAGEN; CROSSLINKING; IMPLANTS (SURGICAL); X RAY PHOTOELECTRON SPECTROSCOPY;

CHITOSAN; HEPATIC TISSUE ENGINEERING; HEPATOCYTES; IMPLANTABLE BIOARTIFICIAL LIVER (IBL);

TISSUE;

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; CHITOSAN; COLLAGEN; HEPARIN;

ANIMAL CELL; ARTICLE; BIOARTIFICIAL ORGAN; BIOCOMPATIBILITY; BLOOD; CELL VIABILITY; CROSS LINKING; LIVER; LIVER CELL; NONHUMAN; RAT; TISSUE ENGINEERING; X RAY PHOTOELECTRON SPECTROSCOPY;

ANIMALIA;

EID: 12444281089     PISSN: 08839115     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883911505049653     Document Type: Article

References (16)

1. Mikos, A.G. and Temenoff, J.S. (2000). Formation of Highly Porous Biodegradable Scaffolds for Tissue Engineering, EJB Electronic Journal of Biotechnology, 3(2): 114-119.
2. Langer, R.S. and Vacanti, J.P. (1999). Tissue Engineering: The Challenges Ahead, Sci. Am., 4: 86-89.
3. Kaihara, S., Borenstein, J., Koka, R., Lalan, S., Ochoa, E.R., Ravens, M., Pien, H., Cunningham, B. and Vacanti, J.P. (2000). Silicon Micromachining to Tissue Engineer Branched Vascular Channels for Liver Fabrication, Tissue Eng., 6(2): 105-117.
4. Edelman, E.R., Nathan, A., Katada, M., Gates, J. and Karnovsky, M.J. (2000). Perivascular Graft Heparin Delivery Using Biodegradable Polymer Wraps, Biomaterials, 21: 2279-2286.
5. Schor, A.M., Schor, S.L. and Kumar, S. (1979). Importance of a Collagen Substratum for Stimulation of Capillary Endothelial Cell Proliferation by Tumor Angiogenesis Factor, Int. J. Cancer, 24: 225.
6. Mori, T., Okumura, M., Matsuura, M., Ueno, K., Tokura, S., Okamoto, Y., Minami, S. and Fujinaga T. (1997). Effect of Chitin and its Derivatives on the Proliferation and Cytokine Production of Fibroblasts In Vitro, Biomaterials, 18: 947-951.
7. Stemberger, A., Ascherl, R. and Kollagen, G.B. (1990). Ein Biomaterial in der Medizin, Hämostaseologie, 10: 164-176.
8. Wang, X.H., Li, D.P., Wang, W.J., Feng, Q.L., Cui, F.Z., Xu, Y.X. and Song, X.H. (2003). Crosslinked Collagen/Chitosan Matrix for Artificial Livers, Biomaterials, 24: 3213-3220.
9. Wang, X.H., Cui, F.Z., Feng, Q.L., Li, J.C. and Zhang, Y.H. (2003). Preparation and Characterization of Collagen/Chitosan Matrices as Potential Biomaterials, J. Bioact. and Comp. Polym., 18(6): 453-467.
10. Gilles, M.A., Hudson, A.Q. and Borders, C.L. (1990). Stability of Water-Soluble Carbodiimides in Aqueous Solutions, Anal. Biochem., 184: 244-248.
11. Seglen, P.O. (1976). Preparation of Isolated Rat Liver Cells, Methods Biol., 13: 29.
12. Ingber, D., Karpp, S., Plopper, G., Hansed, L. and Mooney, D. (1993). Physical Forces and the Mammalian Cell, Academic Press, New York.
13. Hill, G.E. (1998). Cardiopulmonary Bypass-Induced Inflammation: Is it Important? J. Cardiothorac. Vasc. Anesth., 12: 21-25.
14. Wendel, H.P. and Ziemer, G. (1999). Coating-Techniques to Improve the Hemocompatibility of Artificial Surfaces Used for Extracorporeal Circulation, Eur. J. Cardiothorac. Surg., 16: 342-350.
15. Miura, Y., Akimoto, T., Kanazawa, H. and Yagi, K. (1986). Synthesis and Secretion of Protein by Hepatocytes Entrapped within Calcium Alginate, Artif. Org., 10: 460-465.
16. Yin, C., Ying, L., Zhang, P.C., Zhuo, R.X., Kang, E.T., Leong, K.W. and Mao, H.Q. (2003). High Density of Immobilized Galactose Ligand Enhances Hepatocyte Attachment and Function, J. Biomed. Mater. Res., 67: 1093-1104.