메뉴 건너뛰기




Volumn 8, Issue 4, 2003, Pages 277-293

Dose-response relationships of granular bio-durable dusts in rat lungs: Does a cancer threshold exist?

(1)  Roller, Markus a,b  

b NONE   (Germany)

Author keywords

Cancer; Human; Lung; Particles; Rat

Indexed keywords

SILICON DIOXIDE; SILICONE;

EID: 1242336957     PISSN: 11286598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (45)
  • 3
    • 0343446141 scopus 로고    scopus 로고
    • The relevance of the rat lung response to particle overload for human risk assessment: A workshop consensus report
    • ILSI Risk Sciences Institute Workshop Participants. The relevance of the rat lung response to particle overload for human risk assessment: a workshop consensus report. Inhal Toxicol 2000; 12: 1-17.
    • (2000) Inhal Toxicol , vol.12 , pp. 1-17
  • 4
    • 0022833676 scopus 로고
    • Factors limiting the evidence for chemical carcinogenicity of diesel emissions in long-term inhalation experiments
    • Ishinishi N, Koizumi A, McClellan RO, et al. (Eds). Amsterdam, New York, Oxford: Elsevier Sci Publ (Biomed Div)
    • Vostal JJ. Factors limiting the evidence for chemical carcinogenicity of diesel emissions in long-term inhalation experiments. In Ishinishi N, Koizumi A, McClellan RO, et al. (Eds). Carcinogenic and mutagenic effects of diesel engine exhaust. Developments in Toxicology and Environmental Science, Vol 13. Amsterdam, New York, Oxford: Elsevier Sci Publ (Biomed Div), 1986, 381-96.
    • (1986) Carcinogenic and Mutagenic Effects of Diesel Engine Exhaust. Developments in Toxicology and Environmental Science , vol.13 , pp. 381-396
    • Vostal, J.J.1
  • 5
    • 0018151294 scopus 로고
    • Pulmonary clearance and hilar lymph node content in rats after particle exposure
    • Ferin J, Feldstein ML. Pulmonary clearance and hilar lymph node content in rats after particle exposure. Environ Res 1978; 16: 342-52.
    • (1978) Environ Res , vol.16 , pp. 342-352
    • Ferin, J.1    Feldstein, M.L.2
  • 6
    • 0020565324 scopus 로고
    • An overload hypothesis for pulmonary clearance of UICC amosite fibres inhaled by rats
    • Bolton RE, Vincent JH, Jones AD, et al. An overload hypothesis for pulmonary clearance of UICC amosite fibres inhaled by rats. Br J Ind Med 1983; 40: 264-72.
    • (1983) Br J Ind Med , vol.40 , pp. 264-272
    • Bolton, R.E.1    Vincent, J.H.2    Jones, A.D.3
  • 7
    • 0022401304 scopus 로고
    • Kinetics of deposition and clearance of inhaled mineral dusts during chronic exposure
    • Vincent JH, Johnston AM, Jones A.D, et al. Kinetics of deposition and clearance of inhaled mineral dusts during chronic exposure. Br J Ind Med 1985; 42: 707-15.
    • (1985) Br J Ind Med , vol.42 , pp. 707-715
    • Vincent, J.H.1    Johnston, A.M.2    Jones, A.D.3
  • 8
    • 0025766753 scopus 로고
    • Chronic inhalation study findings as a basis for proposing a new occupational dust exposure limit
    • Morrow PE, Muhle H, Mermelstein R. Chronic inhalation study findings as a basis for proposing a new occupational dust exposure limit. J Am Coll Toxicol 1991; 10: 279-89.
    • (1991) J Am Coll Toxicol , vol.10 , pp. 279-289
    • Morrow, P.E.1    Muhle, H.2    Mermelstein, R.3
  • 9
    • 0000525287 scopus 로고
    • Sequence of events in lung carcinogenesis: Initiation and promotion, protooncogenes and tumor suppressor genes, and particulates
    • Mohr U, Dungworth DL, Mauderly JL, et al. (Eds). Washington, DC: ILSI Press
    • Lechner JF, Mauderly JL. Sequence of events in lung carcinogenesis: Initiation and promotion, protooncogenes and tumor suppressor genes, and particulates. In Mohr U, Dungworth DL, Mauderly JL, et al. (Eds). Toxic and carcinogenic effects of solid particles in the respiratory tract. ILSI Monographs. Washington, DC: ILSI Press, 1994, 235-51.
    • (1994) Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. ILSI Monographs , pp. 235-251
    • Lechner, J.F.1    Mauderly, J.L.2
  • 10
    • 0028907783 scopus 로고
    • Lung particle overload: Implications for occupational exposures to particles
    • Oberdörster G. Lung particle overload: Implications for occupational exposures to particles. Regul Toxicol Pharmacol 1995; 27: 123-35.
    • (1995) Regul Toxicol Pharmacol , vol.27 , pp. 123-135
    • Oberdörster, G.1
  • 11
    • 0036153806 scopus 로고    scopus 로고
    • Toxicokinetics and effects of fibrous and nonfibrous particles
    • Oberdörster G. Toxicokinetics and effects of fibrous and nonfibrous particles. Inhal Toxicol 2002; 14: 29-56.
    • (2002) Inhal Toxicol , vol.14 , pp. 29-56
    • Oberdörster, G.1
  • 12
    • 26444516111 scopus 로고    scopus 로고
    • Role of inflammation in the development of rat lung tumors in response to chronic particle exposure
    • Driscoll KE. Role of inflammation in the development of rat lung tumors in response to chronic particle exposure. Inhal Toxicol 1996; 8 suppl: 139-53.
    • (1996) Inhal Toxicol , Issue.8 SUPPL. , pp. 139-153
    • Driscoll, K.E.1
  • 13
    • 77957187311 scopus 로고
    • Lung clearance and retention of toner, utilizing a tracer technique, during chronic inhalation exposure in rats
    • Bellmann B, Muhle H, Creutzenberg O, et al. Lung clearance and retention of toner, utilizing a tracer technique, during chronic inhalation exposure in rats. Fundam Appl Toxicol 1991; 17: 300-13.
    • (1991) Fundam Appl Toxicol , vol.17 , pp. 300-313
    • Bellmann, B.1    Muhle, H.2    Creutzenberg, O.3
  • 15
    • 0003759650 scopus 로고
    • Models of deposition, retention and clearance of particles after dust overloading of lungs in rats
    • Bellmann B, Creutzenberg O, Ale H, et al. Models of deposition, retention and clearance of particles after dust overloading of lungs in rats. Ann Occup Hyg 1994; 38 suppl 1: 303-11.
    • (1994) Ann Occup Hyg , vol.38 , Issue.SUPPL. 1 , pp. 303-311
    • Bellmann, B.1    Creutzenberg, O.2    Ale, H.3
  • 16
    • 27144514320 scopus 로고    scopus 로고
    • Durchführung eines Risikovergleichs zwischen Dieselmotoremissionen und Ottomotoremissionen hinsichtlich ihrer kanzerogenen und nicht-kanzerogenen Wirkungen. Berichte 2/99-Forschungsbericht 297 61 001/01
    • UBA (Umweltbundesamt, Ed). Durchführende Inst.: Fraunhofer Institut für Toxikologie und Aerosolforschung. Bearb.: Mangelsdorf I (Koordination), Aufderheide M, Boehncke A, et al. Berlin: Erich Schmidt
    • UBA (Umweltbundesamt, Ed). Durchführung eines Risikovergleichs zwischen Dieselmotoremissionen und Ottomotoremissionen hinsichtlich ihrer kanzerogenen und nicht-kanzerogenen Wirkungen. Berichte 2/99-Forschungsbericht 297 61 001/01. Durchführende Inst.: Fraunhofer Institut für Toxikologie und Aerosolforschung. Bearb.: Mangelsdorf I (Koordination), Aufderheide M, Boehncke A, et al. Report Nr. UBA FB 99-033. Berlin: Erich Schmidt, 1999.
    • (1999) Berichte 2/99-Forschungsbericht 297 61 001/01
  • 17
    • 0006700454 scopus 로고    scopus 로고
    • Extrapolation modeling of particle deposition and retention from rats to humans
    • Mauderly JL, McCunney RJ (Eds). Washington, London: Taylor and Francis
    • Yu CP. Extrapolation modeling of particle deposition and retention from rats to humans. In Mauderly JL, McCunney RJ (Eds). Particle overload in the rat lung. Implications for human risk assessment. Washington, London: Taylor and Francis, 1996, 279-91.
    • (1996) Particle Overload in the Rat Lung. Implications for Human Risk Assessment , pp. 279-291
    • Yu, C.P.1
  • 18
    • 0033775640 scopus 로고    scopus 로고
    • Mathematical modeling to predict the responses to poorly soluble particles in rat lungs
    • Tran CL, Buchanan D, Miller BG, et al. Mathematical modeling to predict the responses to poorly soluble particles in rat lungs. Inhal Toxicol 2000; 12 suppl 3: 403-9.
    • (2000) Inhal Toxicol , vol.12 , Issue.SUPPL. 3 , pp. 403-409
    • Tran, C.L.1    Buchanan, D.2    Miller, B.G.3
  • 19
    • 1242280303 scopus 로고    scopus 로고
    • Significance of associations between inflammatory and neoplastic processes after exposure to particles
    • Heinrich U Mohr U (Eds). Washington DC: ILSI Press
    • Donaldson K, MacNee W, Jones A, et al. Significance of associations between inflammatory and neoplastic processes after exposure to particles. In Heinrich U Mohr U (Eds). Relationships between acute and chronic effects of air pollution. ILSI Monographs. Washington DC: ILSI Press, 2000, 253-9.
    • (2000) Relationships between Acute and Chronic Effects of Air Pollution. ILSI Monographs , pp. 253-259
    • Donaldson, K.1    MacNee, W.2    Jones, A.3
  • 20
    • 0031218394 scopus 로고    scopus 로고
    • Pulmonary carcinogenicity of inhaled particles and the maximum tolerated dose
    • Oberdörster G. Pulmonary carcinogenicity of inhaled particles and the maximum tolerated dose. Environ Health Perspect 1997; 105 suppl 5: 1347-55.
    • (1997) Environ Health Perspect , vol.105 , Issue.SUPPL. 5 , pp. 1347-1355
    • Oberdörster, G.1
  • 21
    • 0033973405 scopus 로고    scopus 로고
    • Dosimetry of particles in laboratory animals and humans in relationship to issues surrounding lung overload and human health risk assessment: A critical review
    • Miller FJ. Dosimetry of particles in laboratory animals and humans in relationship to issues surrounding lung overload and human health risk assessment: a critical review. Inhal Toxicol 2000; 12: 19-57.
    • (2000) Inhal Toxicol , vol.12 , pp. 19-57
    • Miller, F.J.1
  • 22
    • 1242302583 scopus 로고    scopus 로고
    • Comment to the paper of Driscoll, K.E.: Role of inflammation in the development of rat lung tumors in response to chronic particle exposure
    • letter
    • Roller M. Comment to the paper of Driscoll, K.E.: Role of inflammation in the development of rat lung tumors in response to chronic particle exposure, published on Inhal Toxicol 1996; 8 Suppl: 139-153. Inhal Toxicol 1998; 10: 173-8 (letter).
    • (1998) Inhal Toxicol , vol.10 , pp. 173-178
    • Roller, M.1
  • 23
    • 26444516111 scopus 로고    scopus 로고
    • published on
    • Roller M. Comment to the paper of Driscoll, K.E.: Role of inflammation in the development of rat lung tumors in response to chronic particle exposure, published on Inhal Toxicol 1996; 8 Suppl: 139-153. Inhal Toxicol 1998; 10: 173-8 (letter).
    • (1996) Inhal Toxicol , vol.8 , Issue.SUPPL. , pp. 139-153
  • 24
    • 0003632371 scopus 로고    scopus 로고
    • OSHA Federal Register # 62: 1494-1619. FR Doc. 97-198 Filed 1-9-97
    • OSHA (Occupational Safety and Health Administration) Occupational exposure to methylene chloride. OSHA Federal Register # 62: 1494-1619. FR Doc. 97-198 Filed 1-9-97. http://www.osha-slc.gov/FedReg_osha_data/FED19970110.html. 1997.
    • (1997) Occupational Exposure to Methylene Chloride
  • 25
    • 77957181417 scopus 로고
    • Pulmonary response to toner upon chronic inhalation exposure in rats
    • Muhle H, Bellmann B, Creutzenberg O, et al. Pulmonary response to toner upon chronic inhalation exposure in rats. Fundam Appl Toxicol 1991; 17: 280-99.
    • (1991) Fundam Appl Toxicol , vol.17 , pp. 280-299
    • Muhle, H.1    Bellmann, B.2    Creutzenberg, O.3
  • 26
    • 0034009164 scopus 로고    scopus 로고
    • Comparison of human and rodent lung dosimetry models for particle clearance and retention
    • Kuempel ED: Comparison of human and rodent lung dosimetry models for particle clearance and retention. Drug Chem Toxicol 2000; 23 (1): 203-22.
    • (2000) Drug Chem Toxicol , vol.23 , Issue.1 , pp. 203-222
    • Kuempel, E.D.1
  • 27
    • 26844434119 scopus 로고    scopus 로고
    • Lung tissue responses and sites of particle retention differ between rats and cynomolgus monkeys exposed chronically to diesel exhaust and coal dust
    • Nikula KJ, Avila KJ, Griffith WC, et al. Lung tissue responses and sites of particle retention differ between rats and cynomolgus monkeys exposed chronically to diesel exhaust and coal dust. Fundam Appl Toxicol 1997; 37: 37-53.
    • (1997) Fundam Appl Toxicol , vol.37 , pp. 37-53
    • Nikula, K.J.1    Avila, K.J.2    Griffith, W.C.3
  • 28
    • 77957187684 scopus 로고
    • Clearance of diesel soot particles from rat lung after a subchronic diesel exhaust exposure
    • Griffis LC, Wolff RK, Henderson RF, et al. Clearance of diesel soot particles from rat lung after a subchronic diesel exhaust exposure. Fundam Appl Toxicol 1983; 3: 99-103.
    • (1983) Fundam Appl Toxicol , vol.3 , pp. 99-103
    • Griffis, L.C.1    Wolff, R.K.2    Henderson, R.F.3
  • 29
    • 0021628837 scopus 로고
    • Pulmonary retention of inhaled diesel particles after prolonged exposures to diesel exhaust
    • Chan TL, Lee PS, Hering WE. Pulmonary retention of inhaled diesel particles after prolonged exposures to diesel exhaust. Fundam Appl Toxicol 1984; 4: 624-31.
    • (1984) Fundam Appl Toxicol , vol.4 , pp. 624-631
    • Chan, T.L.1    Lee, P.S.2    Hering, W.E.3
  • 30
    • 0023376017 scopus 로고
    • Alterations in particle accumulation and clearance in lungs of rats chronically exposed to diesel exhaust
    • Wolff RK, Henderson RF, Snipes MB, et al. Alterations in particle accumulation and clearance in lungs of rats chronically exposed to diesel exhaust. Fundam Appl Toxicol 1987; 9: 154-66.
    • (1987) Fundam Appl Toxicol , vol.9 , pp. 154-166
    • Wolff, R.K.1    Henderson, R.F.2    Snipes, M.B.3
  • 31
    • 0031427707 scopus 로고    scopus 로고
    • Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells
    • Driscoll KE, Deyo LC, Carter JM, et al. Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells. Carcinogenesis 1997; 18: 423-30.
    • (1997) Carcinogenesis , vol.18 , pp. 423-430
    • Driscoll, K.E.1    Deyo, L.C.2    Carter, J.M.3
  • 34
    • 0026408922 scopus 로고
    • Neoplastic findings in experimental asbestos studies and conclusions for fiber carcinogenesis in humans
    • Landrigan PhJ, Kazemi H (Eds). The third wave of asbestos disease: exposure to asbestos in place. Public Health Control
    • Pott F. Neoplastic findings in experimental asbestos studies and conclusions for fiber carcinogenesis in humans. In Landrigan PhJ, Kazemi H (Eds). The third wave of asbestos disease: exposure to asbestos in place. Public Health Control. Ann NY Acad Sci 1991; 643: 205-18.
    • (1991) Ann NY Acad Sci , vol.643 , pp. 205-218
    • Pott, F.1
  • 35
    • 0033930302 scopus 로고    scopus 로고
    • Asbestos as reference material for fibre-induced cancer
    • Muhle H, Pott F. Asbestos as reference material for fibre-induced cancer. Int Arch Occup Environ Health 2000; 73 suppl: S53-S59.
    • (2000) Int Arch Occup Environ Health , vol.73 , Issue.SUPPL.
    • Muhle, H.1    Pott, F.2
  • 36
    • 0004656527 scopus 로고    scopus 로고
    • Differences between the classification of man-made vitreous fibres (MMVF) according to the European directive and German legislation: Analysis of scientific data and implications for worker protection
    • Wardenbach P, Pott F, Woitowitz H-J. Differences between the classification of man-made vitreous fibres (MMVF) according to the European directive and German legislation: analysis of scientific data and implications for worker protection. Eur J Oncol 2000; 5 suppl 2: 111-8.
    • (2000) Eur J Oncol , vol.5 , Issue.SUPPL. 2 , pp. 111-118
    • Wardenbach, P.1    Pott, F.2    Woitowitz, H.-J.3
  • 37
    • 1242347612 scopus 로고    scopus 로고
    • Are lung tumours from poorly soluble particles in rats relevant for occupational exposure?
    • 11 - 13 June, 2001, Toulouse, France. IVSS Sektion Chemie, IVSS Sektion Forschung. Proceedings. Paris: Institut National de Recherche et de Securite (INRS)
    • Roller M, Pott F. Are lung tumours from poorly soluble particles in rats relevant for occupational exposure? International Symposium "Poussiè res, fumées et brouillards sur les lieux de travail: risques et prévention", 11 - 13 June, 2001, Toulouse, France. IVSS Sektion Chemie, IVSS Sektion Forschung. Proceedings. Paris: Institut National de Recherche et de Securite (INRS), 2001, 154-9.
    • (2001) International Symposium "Poussières, Fumées et Brouillards sur les Lieux de Travail: Risques et Prévention" , pp. 154-159
    • Roller, M.1    Pott, F.2
  • 38
    • 1242325075 scopus 로고    scopus 로고
    • Lung tumor risk from silica containing dusts - In some cases higher in humans than in rats
    • Heinrich U, Mohr U (Eds). Stuttgart: Fraunhofer IRB Verlag
    • Roller M. Lung tumor risk from silica containing dusts - In some cases higher in humans than in rats. In Heinrich U, Mohr U (Eds). Crucial issues in inhalation research - Mechanistic, clinical and epidemiologic. INIS Monographs. Stuttgart: Fraunhofer IRB Verlag, 2002, 295-307.
    • (2002) Crucial Issues in Inhalation Research - Mechanistic, Clinical and Epidemiologic. INIS Monographs , pp. 295-307
    • Roller, M.1
  • 39
    • 25544444079 scopus 로고    scopus 로고
    • Stellungnahme des Beraterkreises Toxikologie des AGS zur Frage der Einstufung von kristallinem Siliciumdioxid (Quarz [14808-60-7] und Cristobalit [14464-46-1]) in Form von alveolengängigen Stäuben
    • Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA, Ed). Bremerhaven: Wirtschaftsverlag NW
    • Schlüter G. Stellungnahme des Beraterkreises Toxikologie des AGS zur Frage der Einstufung von kristallinem Siliciumdioxid (Quarz [14808-60-7] und Cristobalit [14464-46-1]) in Form von alveolengängigen Stäuben. In Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA, Ed). Quarz - Einstufung, Dosis-Wirkungs-Beziehungen. Workshop vom 07./08. März 2002 in Berlin. Schriftenreihe der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin. Tb131. Bremerhaven: Wirtschaftsverlag NW, 2003, 109-33.
    • (2003) Quarz - Einstufung, Dosis-Wirkungs-Beziehungen. Workshop vom 07./08. März 2002 in Berlin. Schriftenreihe der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin. Tb131 , pp. 109-133
    • Schlüter, G.1
  • 40
    • 0031440526 scopus 로고    scopus 로고
    • Proposed changes in the classification of carcinogenic chemicals in the work area
    • Neumann H-G, Thielmann HW, Filser JG, et al. Proposed changes in the classification of carcinogenic chemicals in the work area. Regul Toxicol Pharmacol 1997; 26: 288-95.
    • (1997) Regul Toxicol Pharmacol , vol.26 , pp. 288-295
    • Neumann, H.-G.1    Thielmann, H.W.2    Filser, J.G.3
  • 44
    • 0028036627 scopus 로고
    • Current perspectives on particulate induced pulmonary tumours
    • Hext PM. Current perspectives on particulate induced pulmonary tumours. Human Exp Toxicol 1994; 13: 700-15.
    • (1994) Human Exp Toxicol , vol.13 , pp. 700-715
    • Hext, P.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.