Expression of IGR-IR and VEGF and trophoblastic proliferative activity in placentas from pregnancies complicated by IUGR

Pathology Research and Practice

Volumn 199, Issue 12, 2003, Pages 803-809

  Gurel, Duygu ^a   Özer, Erdener ^a   Altunyurt, Sabahattin ^a   Guclu, Serkan ^a   Demir, Namik ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Insuline like growth factor receptor; Intrauterine growth retardation; Ki 67; Placenta; Vascular endothelial growth factor

Indexed keywords

FORMALDEHYDE; KI 67 ANTIGEN; SOMATOMEDIN C RECEPTOR; VASCULOTROPIN;

ADULT; ARTICLE; CELL PROLIFERATION; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FETUS; FETUS GROWTH; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRAUTERINE GROWTH RETARDATION; PATHOGENESIS; PLACENTA; PLACENTA INSUFFICIENCY; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

EID: 1242330353     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1078/0344-0338-00499     Document Type: Article

References (28)

1. Benirschke K, Kaufmann P (1995) Pathology of the Human Placenta, 4th ed., pp 363-336. Springer-Verlag, New York
2. Blankenship TN, King BF (1994) Developmental expression of Ki 67 antigen and proliferating cell nuclear antigen in macaque placentas. Dev Dyn 201: 324-333
3. Chan CC, Lao TT, Cheung AN (1999) Apoptotic and proliferative activities in first trimester placentae. Placenta 20: 223-227
4. Clark DE, Smith SK, Sharkey AM, Charnock-Jones DS (1996) Localization of VEGF and expression of its receptors flt and KDR in human placenta throughout pregnancy. Hum Repro 11: 1090-1098.
5. Cotran RS, Schonfield D (1999) Disease of infancy and childhood In: Cotran RS, Kumar V, Collins T (Eds) Robin's Pathologic Basis of Disease, 6th ed., pp 459-491. W.B. Saunders, Philadelphia
6. de Manzoni G, Verlato G, Tomezzoli A, Guglielmi A, Pelosi G, Ricci F, Di Leo A, Cordiano C (1998) Study on Ki-67 immunoreactivity as a prognostic indicator in patients with advanced gastric cancer. Jpn J Clin Oncol 28: 534-537
7. Fang J, Furesz TC, Lurent RS, Smith CH, Fant ME (1997) Spatial polarization of insulin-like growth factor receptors on the human syncytiotrophoblast. Pediatr Res 41: 258-265
8. Ferrara N, Houck KA, Jakeman LB, Winer J, Leung DW (1991) The vascular endothelial growth factor family of polypeptides. J Cell Biochem 47: 211-218
9. Garnica AD, Chan YW (1996) The role of the placenta in fetal nutrition and growth. J Am Coll Nutr 15: 206-222
10. Gersell DJ, Kraus FT (1994) Diseases of the placenta In: Kurman RJ (Ed) Blaustein's Pathology of The Female Genital Tract, 4th ed., pp 975-1048. Springer-Verlag, New York
11. Holmes R, Porter H, Newcomb P, Holly JM, Soothill P (1999) An immunohistochemical study of type I insulin-like growth factor receptors in the placentae of pregnancies with appropriately grown or growth restricted fetuses. Placenta 20: 325-330
12. Khaliq A, Dunk C, Jiang J, Shams M, Li XF, Acevedo C, Weich H, Whittle M, Ahmed A (1999) Hypoxia down-regulates placental growth factor, whereas fetal growth restriction up-regulates placenta growth factor expression: molecular evidence for "placental hyperoxia" in intrauterine growth restriction. Lab Invest 79: 151-170
13. Kovalovszki L, Veszelovszky I, Benko G, Villanyi E (1987) Intrauterine growth of infants with chorioamnionitis. Acta. Paediatr Hung 28: 229-235
14. Lacroix MC, Servely JL, Kann G (1995) IGF-I and IGF-II receptors in the sheep placenta: evolution during the course of pregnancy. J Endocrinol 144: 179-191
15. Lin CC, Santolaya-Forgas J (1998) Current concept of fetal growth restriction: Part I. Causes, classification, and pathophysiology. Obstet Gynecol 92: 1044-1055
16. Maruo T, Murata K, Matsuo H, Samoto T, Mochizuki M (1995) Insulin like growth factor I as a local regulator of proliferation and differantiated function of the human trophoblast in early pregnancy. Early Pregnancy 1: 54-61
17. Neufeld G, Tessler S, Gitay-Goren H, Cohen T, Levi BZ (1991) Vascular endothelial growth factor and its receptors. Prog Growth Factor Res 5: 89-97
18. Ozer E, Sis B, Ozen E, Sakizli M, Canda T, Sarioglu S (2002) BRCA-1, c-ebB-2 and H-ras gene expressions in young women with breast cancer: An immunohistochemical study. Appl Immunohistochem Molecul Morphol 8: 12-18
19. Pardi G, Marconi AM, Cetin I (1997) Pathophysiology of intrauterine growth retardation: role of the placenta. Acta Pediatr 423: 170-172
20. Rayburn W. Sander C. Compton A (1989) Histologic examination of the placenta in the growth-retarded fetus. Am J Perinatol 6: 58-61
21. Reece EA, Goldstein I, Hobbins CJ (1994) Fundamentals of obstetric & gynecologic ultrasound, pp 191-198. Appleton & Lange, Connecticut
22. Russell P (1995) Infections of the placental villi (villitis) In: Fox H, Wells M (Eds) Obstetrical and Gynecological Pathology. 4th ed., pp 1541-1558. Churchill Livingstone, New York
23. Salafia CM, Minior VK, Pezzullo JC, Popek EJ, Rozenkrantz TS, Vintzileos AM (1995) Intrauterine growth restriction in infants of less than thirty-two weeks gestation: Associated placental pathologic features. Am J Obstet Gynecol 173: 1049-1057
24. Shiraishi S, Nakagawa K, Kinukawa N, Nakano H, Sueishi K (1996) Immunohistochemical localization of vascular endothelial growth-factor in the human placenta. Placenta 17: 111-121
25. Torry DS, Torry RJ (1997) Angiogenesis and expression of vascular endothelial growth factor in endometrium and placenta. Am J Repro Immunol 37: 21-29
26. Wells M, Mohande E (1995) Pathology of the pregnant uterus In: Fox H, Wells M (Eds) Obstetrical and Gynecological Pathology, 4th ed., pp 1509-1539. Churchill Livingstone, New York
27. Williams MC, O'Brien WF, Nelson RN, Spellacy WN (2000) Histologic chorioamnionitis is associated with fetal growth restriction in term and preterm infants. Am J Obstet Gynecol 183: 1094-1099
28. Vorherr H (1982) Factors influencing fetal growth Am J Obstet Gynecol 142: 577-588