Lympho-myeloid chimerism achieved by spleen graft of green fluorescent protein transgenic rat in a combined pancreas transplantation model (TI03-029)

Transplant Immunology

Volumn 12, Issue 2, 2004, Pages 115-122

  Sakuma, Yasunaru ^a   Sato, Yuki ^a   Inoue, Seiichiro ^a   Kaneko, Takashi ^a   Hakamata, Yoji ^a   Takahashi, Masafumi ^a   Murakami, Takashi ^a   Kobayashi, Eiji ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

GFP transgenic rat; Multilineage chimerism; Pancreas transplantation; Spleen transplantation

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ARTICLE; CELL LINEAGE; CELL SIZE; CHIMERA; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; GRANULOCYTE; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE; MALE; NONHUMAN; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; RAT; SPLEEN TRANSPLANTATION; T LYMPHOCYTE; TRANSGENIC ANIMAL;

EID: 1242329010     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2003.10.002     Document Type: Article

References (27)

1. Gleit Z.L., Fuchimoto Y., Yamada K., Melendy E., Scheier-Dolberg R., Monajati L., et al. Variable relationship between chimerism and tolerance after hematopoietic cell transplantation without myelosuppressive conditioning. Transplantation. 74:(11):2002;1535-1544.
2. Buhler L.H., Spitzer T.R., Sykes M., Sachs D.H., Delmonico F.L., Tolkoff-Rubin N., et al. Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease. Transplantation. 74:(10):2002;1405-1409.
3. Millan M.T., Shizuru J.A., Hoffmann P., Dejbakhsh-Jones S., Scandling J.D., Grumet F.C., et al. Mixed chimerism and immunosuppressive drug withdrawal after HLA-mismatched kidney and hematopoietic progenitor transplantation. Transplantation. 73:(9):2002;1386-1391.
4. Strober S., Dhillon M., Schubert M., Holm B., Engleman E., Benike C., et al. Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation. N Engl J Med. 321:(1):1989;28-33.
5. Shapiro R., Rao A.S., Fontes P., Zeevi A., Jordan M., Scantlebury V.P., et al. Combined simultaneous kidney/bone marrow transplantation. Transplantation. 60:(12):1995;1421-1425.
6. Bitter-Suermann H. Survival of unmodified spleen allografts in rats. Nature. 247:(441):1974;465-466.
7. Sun J., McCaughan G.W., Gallagher N.D., Sheil A.G., Bishop G.A. Deletion of spontaneous rat liver allograft acceptance by donor irradiation. Transplantation. 60:(3):1995;233-236.
8. Ko S., Deiwick A., Jager M.D., Dinkel A., Rohde F., Fischer R., et al. The functional relevance of passenger leukocytes and microchimerism for heart allograft acceptance in the rat. Nat Med. 5:(11):1999;1292-1297.
9. Kobayashi E., Lord R., Green M., Kamada N., Toyama N., Miyata M., et al. The fate of donor splenic lymphocytes in a long-surviving host after combined pancrea/spleen transplantation in the rat. Transplant Proc. 31:(6):1999;2665- 2667.
10. Hakamata Y., Tahara K., Uchida H., Sakuma Y., Nakamura M., Kume A., et al. Green fluorescent protein-transgenic rat: a tool for organ transplantation research. Biochem Biophys Res Commun. 286:(4):2001;779-785.
11. Kobayashi E., Kamada N., Toyama N., Delriviere L., Goto S., Enosawa S., et al. Successful methods of pancreas transplantation in the rat using a cuff technique. Aust N Z J Surg. 64:(7):1994;491-493.
12. Starzl T.E., Demetris A.J., Murase N., Ildstad S., Ricordi C., Trucco M. Cell migration, chimerism, and graft acceptance. Lancet. 339:(8809):1992;1579- 1582.
13. Bishop G.A., Sun J., Sheil A.G., McCaughan G.W. High-dose/activation- associated tolerance: a mechanism for allograft tolerance. Transplantation. 64:(10):1997;1377-1382.
14. Sykes M., Preffer F., McAfee S., Saidman S.L., Weymouth D., Andrews D.M., et al. Mixed lymphohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation. Lancet. 353:(9166):1999;1755-1759.
15. Wekerle T., Kurtz J., Ito H., Ronquillo J.V., Dong V., Zhao G., et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med. 6:(4):2000;464-469.
16. Duncan W.R., Bitter-Suermann H., Stepkowski S.M. Induction of transplantation tolerance in rats by spleen allografts. III. The role of T suppressor cells in the induction of specific unresponsiveness. Transplantation. 44:(4):1987;553-558.
17. Suzuki H., Li X.H., Miyamoto M., Sano T., Hattori Y., Yamashita A. Induction of transplantation tolerance in adult rats by vascularized spleen transplantation. Transplantation. 64:(4):1997;650-654.
18. Westra A.L., Petersen A.H., Prop J., Wildevuur C.R. The combi-effect - reduced rejection of the heart by combined transplantation with the lung or spleen. Transplantation. 52:(6):1991;952-955.
19. Ramsdell F., Fowlkes B.J. Clonal deletion vs. clonal anergy: the role of the thymus in inducing self tolerance. Science. 248:(4961):1990;1342-1348.
20. Taniguchi H., Abe M., Shirai T., Fukao K., Nakauchi H. Reconstitution ratio is critical for alloreactive T cell deletion and skin graft survival in mixed bone marrow chimeras. J Immunol. 155:(12):1995;5631-5636.
21. Gleit Z.L., Cameron A.M., Fuchimoto Y., Melendy E., Monajati L., Coburn R.C., et al. Persistent chimerism despite antidonor MHC in vitro responses in miniature swine following allogeneic hematopoietic cell transplantation. Transplantation. 74:(9):2002;1260-1266.
22. Ildstad S.T., Sachs D.H. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature. 307:(5947):1984;168-170.
23. Richter N., Raddatz G., Steinhoff G., Schafers H.J., Schlitt H.J. Transmission of donor lymphocytes in clinical lung transplantation. Transplant Int. 7:(6):1994;414-419.
24. Schlitt H.J., Raddatz G., Steinhoff G., Wonigeit K., Pichlmayr R. Passenger lymphocytes in human liver allografts and their potential role after transplantation. Transplantation. 56:(4):1993;951-955.
25. + T cells in the rat. Immunology. 101:(2):2000;178-184.
26. Godden U., Herbert J., Stewart R.D., Roser B. A novel cell type carrying both Th and Tc/s markers in the blood of cyclosporine-treated, allografted rats. Transplantation. 39:(6):1985;624-628.
27. Zuckermann F.A., Husmann R.J. Functional and phenotypic analysis of porcine peripheral blood CD4/CD8 double-positive T cells. Immunology. 87:(3):1996;500-512.