PGP9.5 mRNA could contribute to the molecular-based diagnosis of medullary thyroid carcinoma

European Journal of Cancer

Volumn 40, Issue 4, 2004, Pages 614-618

  Takano, T ^a   Miyauchi, A ^b   Matsuzuka, F ^b   Yoshida, H ^b   Nakata, Y ^a   Kuma, K ^b   Amino, N ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KUMA HOSPITAL   (Japan)

Author keywords

Fine needle aspiration biopsy; Medullary thyroid carcinoma; PGP9.5

Indexed keywords

CALCITONIN; CARCINOEMBRYONIC ANTIGEN; GENE PRODUCT; HYDROLASE; MESSENGER RNA; PROTEIN GENE PRODUCT 9.5; PROTEIN RET; TUMOR MARKER; UBIQUITIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; ASPIRATION BIOPSY; CANCER DIAGNOSIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE MARKER; FAMILIAL CANCER; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SCHOOL CHILD; THYROID GLAND; THYROID MEDULLARY CARCINOMA;

EID: 1242316323     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2003.11.016     Document Type: Article

References (18)

1. Hamburger J.I. Diagnosis of thyroid nodules by fine needle biopsy. use and abuse J. Clin. Endocrinol. Metab. 79:1994;335-339.
2. Takano T., Amino N. Cancer-specific mRNAs in thyroid carcinomas. detection, use, and their implication in thyroid carcinogenesis Endocr. J. 49:2002;97-107.
3. Takano T., Sumizaki H., Amino N. Detection of CD44 variants in fine needle aspiration biopsies of thyroid tumor by RT-PCR. J. Exp. Clin. Cancer Res. 16:1997;267-271.
4. Takano T., Miyauchi A., Yokozawa T.et al. Accurate and objective preoperative diagnosis of thyroid papillary carcinomas by reverse transcription-PCR detection of oncofetal fibronectin messenger RNA in fine-needle aspiration biopsies. Cancer Res. 58:1998;4913-4917.
5. Chong G.C., Beahrs O.H., Sizemore G.W., Woolner L.H. Medullary carcinoma of the thyroid gland. Cancer. 35:1975;695-704.
6. Takano T., Miyauchi A., Matsuzuka F.et al. Preoperative diagnosis of medullary thyroid carcinoma by RT-PCR using RNA extracted from leftover cells within a needle used for fine needle aspiration biopsy. J. Clin. Endocrinol. Metab. 84:1999;951-955.
7. Wilkinson K.D., Lee K.M., Deshpande S., Duerksen-Hughes P., Boss J.M., Pohl J. The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase. Science. 246:1989;670-673.
8. Schofield J.N., Day I.N., Thompson R.J., Edwards Y.H. PGP9.5, a ubiquitin C-terminal hydrolase; pattern of mRNA and protein expression during neural development in the mouse. Brain Res. Dev. Brain Res. 85:1995;229-238.
9. Hochstrasser M. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30:1996;405-439.
10. Hanna F.W., Ardill J.E., Johnston C.F.et al. Regulatory peptides and other neuroendocrine markers in medullary carcinoma of the thyroid. J. Endocrinol. 152:1997;275-281.
11. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate- phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
12. Takano T., Miyauchi A., Matsuzuka F., Kuma K., Amino N. Expression of oncofetal fibronectin messenger ribonucleic acid in fibroblasts in the thyroid. a possible cause of false positive results in molecular-based diagnosis of thyroid carcinomas J. Clin. Endocrinol. Metab. 85:2000;765-768.
13. Takano T., Miyauchi A., Yokozawa T.et al. Preoperative diagnosis of thyroid papillary and anaplastic carcinomas by real-time quantitative reverse transcription-polymerase chain reaction of oncofetal fibronectin messenger RNA. Cancer Res. 59:1999;4542-4545.
14. Spataro V., Norbury C., Harris A.L. The ubiquitin-proteasome pathway in cancer. Br. J. Cancer. 77:1998;448-455.
15. Hibi K., Westra W.H., Borges M., Goodman S., Sidransky D., Jen J. PGP9.5 as a candidate tumor marker for non-small-cell lung cancer. Am. J. Pathol. 155:1999;711-715.
16. Tezel E., Hibi K., Nagasaka T., Nakao A. PGP9.5 as a prognostic factor in pancreatic cancer. Clin. Cancer Res. 6:2000;4764-4767.
17. Yamazaki T., Hibi K., Takase T.et al. PGP9.5 as a marker for invasive colorectal cancer. Clin. Cancer Res. 8:2002;192-195.
18. Olerud J.E., Chiu D.S., Usui M.L., Gibran N.S., Ansel J.C. Protein gene product 9.5 is expressed by fibroblasts in human cutaneous wounds. J. Invest. Dermatol. 111:1998;565-572.