CD109 represents a novel branch of the α2-macroglobulin/complement gene family

Gene

Volumn 327, Issue 2, 2004, Pages 171-183

  Solomon, Keith R ^a   Sharma, Parul ^b   Chan, Melvin ^b   Morrison, Paul T ^c   Finberg, Robert W ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

CD109; Complement; Macroglobulin; Motifs; PCR cloning; Phylogenic; Thioester

Indexed keywords

ALPHA 2 MACROGLOBULIN; AMINO ACID; CD109 GLYCOPROTEIN; FURIN; THIOESTER; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CHROMOSOME 6Q; CONTROLLED STUDY; DNA BINDING MOTIF; DNA SEQUENCE; ENDOTHELIUM CELL; ESCHERICHIA COLI; EXON; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR CLONING; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; T LYMPHOCYTE ACTIVATION; THROMBOCYTE; TUMOR;

MAMMALIA;

EID: 1242316184     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2003.11.025     Document Type: Article

References (36)

1. Anthony R., Morrison L., MacSween R.N., Whaley K. Biosynthesis of complement components by cultured rat hepatocytes. Biochem. J. 232:1985;93-98.
2. Brashem-Stein C., Nugent D., Bernstein I.D. Characterization of an antigen expressed on activated human T cells and platelets. J. Immunol. 140:1988;2330-2333.
3. Chan A.C., Atkinson J.P. Identification and structural characterization of two incompletely processed forms of the fourth component of human complement. J. Clin. Invest. 72:1983;1639-1649.
4. Dodds A.W., Law S.K. The phylogeny and evolution of the thioester bond-containing proteins C3, C4 and alpha 2-macroglobulin. Immunol. Rev. 166:1998;15-26.
5. Eisenhaber B., Bork P., Eisenhaber F. Post-translational GPI lipid anchor modification of proteins in kingdoms of life: analysis of protein sequence data from complete genomes. Protein Eng. 14:2001;17-25.
6. Fong K.Y., Botto M., Walport M.J., So A.K. Genomic organization of human complement component C3. Genomics. 7:1990;579-586.
7. Haregewoin A., Solomon K., Hom R.C., Soman G., Bergelson J.M., Bhan A.K., Finberg R.W. Cellular expression of a GPI-linked T cell activation protein. Cell. Immunol. 156:1994;357-370.
8. Harpel P.C., Hayes M.B., Hugli T.E. Heat-induced fragmentation of human alpha 2-macroglobulin. J. Biol. Chem. 254:1979;8669-8678.
9. Henikoff S. A reconsideration of the mechanism of position effect. Genetics. 138:1994;1-5.
10. Henikoff S., Henikoff J.G. Position-based sequence weights. J. Mol. Biol. 243:1994;574-578.
11. Henikoff S., Henikoff J.G. Protein family classification based on searching a database of blocks. Genomics. 19:1994;97-107.
12. Hussain M.M. Structural, biochemical and signaling properties of the low-density lipoprotein receptor gene family. Front. Biosci. 6:2001;D417-D428.
13. Kan C.C., Solomon E., Belt K.T., Chain A.C., Hiorns L.R., Fey G. Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus. Proc. Natl. Acad. Sci. U. S. A. 82:1985;2282-2286.
14. Kelton J.G., Smith J.W., Horsewood P., Humbert J.R., Hayward C.P., Warkentin T.E. Gov a/b alloantigen system on human platelets. Blood. 75:1990;2172-2176.
15. Kelton J.G., Smith J.W., Horsewood P., Warner M.N., Warkentin T.E., Finberg R.W., Hayward C.P. ABH antigens on human platelets: expression on the glycosyl phosphatidylinositol-anchored protein CD109. J. Lab. Clin. Med. 132:1998;142-148.
16. Levashina E.A., Moita L.F., Blandin S., Vriend G., Lagueux M., Kafatos F.C. Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae. Cell. 104:2001;709-718.
17. Lin M., Sutherland D.R., Horsfall W., Totty N., Yeo E., Nayar R., Wu X.F., Schuh A.C. Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins. Blood. 99:2002;1683-1691.
18. Lundwall A.B., Wetsel R.A., Kristensen T., Whitehead A.S., Woods D.E., Ogden R.C., Colten H.R., Tack B.F. Isolation and sequence analysis of a cDNA clone encoding the fifth complement component. J. Biol. Chem. 260:1985;2108-2112.
19. Meilinger M., Gschwentner C., Burger I., Haumer M., Wahrmann M., Szollar L., Nimpf J., Huettinger M. Metabolism of activated complement component C3 is mediated by the low density lipoprotein receptor-related protein/alpha(2)- macroglobulin receptor. J. Biol. Chem. 274:1999;38091-38096.
20. Moon K.E., Gorski J.P., Hugli T.E. Complete primary structure of human C4a anaphylatoxin. J. Biol. Chem. 256:1981;8685-8692.
21. Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. Prediction of the coding sequences of unidentified human genes: XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6:1999;63-70.
22. Nielsen H., Engelbrecht J., Brunak S., von Heijne G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10:1997;1-6.
23. Schneider W.J. Vitellogenin receptors: oocyte-specific members of the low-density lipoprotein receptor supergene family. Int. Rev. Cyt. 166:1996;103-137.
24. Schuh A.C., Watkins N.A., Nguyen Q., Harmer N.J., Lin M., Prosper J.Y., Campbell K., Sutherland D.R., Metcalfe P., Horsfall W., Ouwehand W.H. A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens. Blood. 99:2002;1692-1698.
25. Sim R.B., Sim E. Autolytic fragmentation of complement components C3 and C4 and its relationship to cavalent binding activity. Ann. N.Y. Acad. Sci. 421:1983;259-276.
26. Solomon K.R. (GPI)-Anchored Proteins Expressed on Lymphocytes. 1996;Harvard University, Cambridge. 187 pp.
27. Solomon K.R., Mallory M.A., Finberg R.W. Determination of the non-ionic detergent insolubility and phosphoprotein associations of glycosylphosphatidylinositol-anchored proteins expressed on T cells. Biochem. J. 334(Pt. 2):1998;325-333.
28. Suciu-Foca N., Reed E., Rubinstein P., MacKenzie W., Ng A.K., King D.W. A late-differentiation antigen associated with the helper inducer function of human T cells. Nature. 318:1985;465-467.
29. Sunyer J.O., Lambris J.D. Evolution and diversity of the complement system of poikilothermic vertebrates. Immunol. Rev. 166:1998;39-57.
30. Sunyer J.O., Tort L., Lambris J.D. Structural C3 diversity in fish: characterization of five forms of C3 in the diploid fish Sparus aurata. J. Immunol. 158:1997;2813-2821.
31. Sunyer J.O., Zarkadis I., Sarrias M.R., Hansen J.D., Lambris J.D. Cloning, structure, and function of two rainbow trout Bf molecules. J. Immunol. 161:1998;4106-4114.
32. Sutherland D.R., Yeo E.L. Cluster report: CDw109. Leukocyte Typing. vol. V:1995;1767-1769 Oxford Univ. Press, Oxford.
33. Sutherland D.R., Yeo E.L. Cluster report: CD109. Leukocyte Typing. vol. VI:1998;714-716 Garland Publishing, London.
34. Sutherland D.R., Yeo E., Ryan A., Mills G.B., Bailey D., Baker M.A. Identification of a cell-surface antigen associated with activated T lymphoblasts and activated platelets. Blood. 77:1991;84-93.
35. Tack B.F. The beta-Cys-gamma-Glu thiolester bond in human C3, C4, and alpha 2-macroglobulin. Springer Semin. Immunopathol. 6:1983;259-282.
36. Thogersen I.B., Hammes S.R., Rubenstein D.S., Pizzo S.V., Valnickova Z., Enghild J.J. New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor. Biochim. Biophys. Acta. 1598:2002;131-139.