-
1
-
-
0037836114
-
Methotrexate inhibits interleukin-6 production in patients with juvenile rheumatoid arthritis
-
Aggarwal, A., Misra, R. (2003) Methotrexate inhibits interleukin-6 production in patients with juvenile rheumatoid arthritis. Rheumatol. Int. 23: 134-137
-
(2003)
Rheumatol. Int.
, vol.23
, pp. 134-137
-
-
Aggarwal, A.1
Misra, R.2
-
2
-
-
0011949799
-
Inhibition of folate-dependent enzymes by methotrexate polyglutamates
-
Goldman, I. D. (ed.) Pergamon Press, Oxford
-
Allegra, C. J., Drake, J, C., Jolivet, J., Chabner, B. A. (1984) Inhibition of folate-dependent enzymes by methotrexate polyglutamates. In: Goldman, I. D. (ed.) Proceedings of second workshop on foly and antifoly polyglutamates. Pergamon Press, Oxford, pp 348-359
-
(1984)
Proceedings of Second Workshop on Foly and Antifoly Polyglutamates
, pp. 348-359
-
-
Allegra, C.J.1
Drake, J.C.2
Jolivet, J.3
Chabner, B.A.4
-
3
-
-
0022637441
-
Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase, and 5′-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide
-
Baggott, J. E., Vaughn, W. H., Hudson, B. B. (1986) Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase, and 5′-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide. Biochem. J. 236: 193-200
-
(1986)
Biochem. J.
, vol.236
, pp. 193-200
-
-
Baggott, J.E.1
Vaughn, W.H.2
Hudson, B.B.3
-
4
-
-
0015619772
-
Polygammaglutamyl metabolites of methotrexate
-
Baugh, C. M., Kurumdieck, C. L., Nair, M. G. (1973) Polygammaglutamyl metabolites of methotrexate. Biochem. Biophys. Res. Commun. 52: 27-34
-
(1973)
Biochem. Biophys. Res. Commun.
, vol.52
, pp. 27-34
-
-
Baugh, C.M.1
Kurumdieck, C.L.2
Nair, M.G.3
-
5
-
-
0030048946
-
Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa
-
Bentley, A. M., Hamid, Q., Robinson, D. S., Schotman, E., Meng, Q. Assoufi, B., Kay, A. B., Durham, S. R. (1996) Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am. J. Respir. Crit. Care Med. 153: 551-556
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.153
, pp. 551-556
-
-
Bentley, A.M.1
Hamid, Q.2
Robinson, D.S.3
Schotman, E.4
Meng, Q.5
Assoufi, B.6
Kay, A.B.7
Durham, S.R.8
-
6
-
-
0025967399
-
Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells
-
Crostein, B. N., Eberle, M. A., Gruber, H. E., Levin, R. I. (1991) Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc. Natl Acad. Sci. USA 88: 2441-2445
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2441-2445
-
-
Crostein, B.N.1
Eberle, M.A.2
Gruber, H.E.3
Levin, R.I.4
-
7
-
-
0025946051
-
Methotrexate in the treatment of steroid-dependent asthma
-
Dyer, P. D., Vaughan, T. R., Weber, R. W. (1991) Methotrexate in the treatment of steroid-dependent asthma. J. Allergy Clin. Immunol. 88: 208-212
-
(1991)
J. Allergy Clin. Immunol.
, vol.88
, pp. 208-212
-
-
Dyer, P.D.1
Vaughan, T.R.2
Weber, R.W.3
-
8
-
-
0028123760
-
Mechanisms of methotrexate action in rheumatoid arthritis. Selective decrease in synovial collagenase gene expression
-
Firestein, G. S., Paine, M. M., Boyle, D. L. (1994) Mechanisms of methotrexate action in rheumatoid arthritis. Selective decrease in synovial collagenase gene expression. Arthritis Rheum. 37: 193-200
-
(1994)
Arthritis Rheum.
, vol.37
, pp. 193-200
-
-
Firestein, G.S.1
Paine, M.M.2
Boyle, D.L.3
-
9
-
-
0023883056
-
Methotrexate in rheumatoid arthritis
-
Furst, D. E., Kremer, J. M. (1988) Methotrexate in rheumatoid arthritis. Arthritis Rheum. 31: 305-314
-
(1988)
Arthritis Rheum.
, vol.31
, pp. 305-314
-
-
Furst, D.E.1
Kremer, J.M.2
-
10
-
-
0028905673
-
Effect of methotrexate on asthmatic reaction in sensitized guinea pigs
-
Gonokami, Y., Keane, S., Kurokawa, M., Adachi, M. (1995) Effect of methotrexate on asthmatic reaction in sensitized guinea pigs. Int. Arch. Allergy Immunol. 106: 410-415
-
(1995)
Int. Arch. Allergy Immunol.
, vol.106
, pp. 410-415
-
-
Gonokami, Y.1
Keane, S.2
Kurokawa, M.3
Adachi, M.4
-
11
-
-
0023836669
-
Studies on the effect of methotrexate on macrophage function
-
Hu, S. K., Mitcho, Y. L., Oronsky, A. L., Kerwar, S. S. (1998) Studies on the effect of methotrexate on macrophage function. J. Rheumatol. 15: 206-209
-
(1998)
J. Rheumatol.
, vol.15
, pp. 206-209
-
-
Hu, S.K.1
Mitcho, Y.L.2
Oronsky, A.L.3
Kerwar, S.S.4
-
12
-
-
34250945149
-
Versuchsanordnung zu Untersuchungen an der Bronchialmuskultur
-
Konzett, H., Rössler, R. (1940) Versuchsanordnung zu Untersuchungen an der Bronchialmuskultur. Arch. Exp. Path. Pharmacol. 195: 71-77
-
(1940)
Arch. Exp. Path. Pharmacol.
, vol.195
, pp. 71-77
-
-
Konzett, H.1
Rössler, R.2
-
13
-
-
0036280483
-
Pulmonary function changes and immunomodulation of cytokine expression by zafirlukast after sensitization and allergen challenge in brown norway rats
-
Lin, C. C., Lin, C. Y., Liaw, S. F., Chen, A. (2002) Pulmonary function changes and immunomodulation of cytokine expression by zafirlukast after sensitization and allergen challenge in brown norway rats. Clin. Exp. Allergy 32: 960-966
-
(2002)
Clin. Exp. Allergy
, vol.32
, pp. 960-966
-
-
Lin, C.C.1
Lin, C.Y.2
Liaw, S.F.3
Chen, A.4
-
14
-
-
0030791292
-
Low-dose methotrexate spares steroid usage in steroid-dependent asthmatic patients
-
Marin, M. G. (1997) Low-dose methotrexate spares steroid usage in steroid-dependent asthmatic patients. Chest 112: 29-33
-
(1997)
Chest
, vol.112
, pp. 29-33
-
-
Marin, M.G.1
-
15
-
-
0017362502
-
Inhibition of the immune response by rapamycin, a new antifungal antibiotic
-
Martel, R. R., Klicius, J., Galet, S. (1977) Inhibition of the immune response by rapamycin, a new antifungal antibiotic. Can. J. Physiol. Pharmacol. 55: 48-51
-
(1977)
Can. J. Physiol. Pharmacol.
, vol.55
, pp. 48-51
-
-
Martel, R.R.1
Klicius, J.2
Galet, S.3
-
16
-
-
0032456683
-
The synthesis and biological evaluation of new methotrexate derivatives in rheumatoid arthritis
-
Matsuoka, H., Mihara, M, (1998) The synthesis and biological evaluation of new methotrexate derivatives in rheumatoid arthritis. Drugs Future 23: 1015-1022
-
(1998)
Drugs Future
, vol.23
, pp. 1015-1022
-
-
Matsuoka, H.1
Mihara, M.2
-
17
-
-
8044234375
-
Antirheumatic agents: Novel methotrexate derivatives bearing a benzoxazine or benzothiazine moiety
-
Matsuoka, H., Ohi, N., Mihara, M., Suzuki, H., Miyamoto, K., Maruyama, N., Tsuji, K., Kato, N., Akimoto, T., Takeda, Y., Yano, K., Kuroki, T. (1997) Antirheumatic agents: novel methotrexate derivatives bearing a benzoxazine or benzothiazine moiety. J. Med. Chem. 40: 105-111
-
(1997)
J. Med. Chem.
, vol.40
, pp. 105-111
-
-
Matsuoka, H.1
Ohi, N.2
Mihara, M.3
Suzuki, H.4
Miyamoto, K.5
Maruyama, N.6
Tsuji, K.7
Kato, N.8
Akimoto, T.9
Takeda, Y.10
Yano, K.11
Kuroki, T.12
-
18
-
-
0000848736
-
Control of respiratory frequency
-
Mead, J. (1960) Control of respiratory frequency. J. Appl. Physiol. 15: 325-336
-
(1960)
J. Appl. Physiol.
, vol.15
, pp. 325-336
-
-
Mead, J.1
-
19
-
-
0030273493
-
In vitro and in vivo biological activities of a novel nonpoly-glutamable anti-folate, MX-68
-
Mihara, M., Urakawa, K., Takagi, N., Moriya, Y., Takeda, Y. (1996) In vitro and in vivo biological activities of a novel nonpoly-glutamable anti-folate, MX-68. Immunopharmacology 35: 41-46
-
(1996)
Immunopharmacology
, vol.35
, pp. 41-46
-
-
Mihara, M.1
Urakawa, K.2
Takagi, N.3
Moriya, Y.4
Takeda, Y.5
-
20
-
-
0030740758
-
A novel antifolate, MX-68, inhibits the development of autoimmune disease in MRL/lpr mice
-
Mihara, M., Takagi, N., Urakawa, K., Moriya, Y., Takeda, Y. A. (1997a) A novel antifolate, MX-68, inhibits the development of autoimmune disease in MRL/lpr mice. Int. Arch. Allergy Immunol. 113: 454-459
-
(1997)
Int. Arch. Allergy Immunol.
, vol.113
, pp. 454-459
-
-
Mihara, M.1
Takagi, N.2
Urakawa, K.3
Moriya, Y.4
Takeda, Y.A.5
-
21
-
-
0030690070
-
Immunosuppressive properties of MX-68, a novel unpolyglutamatable antifolate
-
Mihara, M., Suzuki, T., Kaneko, E., Takagi, N., Takeda, Y. (1997b) Immunosuppressive properties of MX-68, a novel unpolyglutamatable antifolate. Biol. Pharm. Bull. 20: 1071-1075
-
(1997)
Biol. Pharm. Bull.
, vol.20
, pp. 1071-1075
-
-
Mihara, M.1
Suzuki, T.2
Kaneko, E.3
Takagi, N.4
Takeda, Y.5
-
22
-
-
0029146704
-
Effect of some immunosuppressors on allergic bronchial inflammation and airway hyperresponsiveness in mice
-
Nagai, H., Yamaguchi, S., Tanaka, H., Inagaki, N. (1995a) Effect of some immunosuppressors on allergic bronchial inflammation and airway hyperresponsiveness in mice. Int. Arch. Allergy Immunol. 108: 189-195
-
(1995)
Int. Arch. Allergy Immunol.
, vol.108
, pp. 189-195
-
-
Nagai, H.1
Yamaguchi, S.2
Tanaka, H.3
Inagaki, N.4
-
23
-
-
0028970747
-
The effect of thromboxane A2 receptor antagonist BAY-u-3405 on experimental allergic reactions
-
Nagai, H., Takeda, H., Yamaguchi, S., Tanaka, H., Matsuo, A., Inagaki, N. (1995b) The effect of thromboxane A2 receptor antagonist BAY-u-3405 on experimental allergic reactions. Prostaglandins 50: 75-87
-
(1995)
Prostaglandins
, vol.50
, pp. 75-87
-
-
Nagai, H.1
Takeda, H.2
Yamaguchi, S.3
Tanaka, H.4
Matsuo, A.5
Inagaki, N.6
-
24
-
-
0031045582
-
Effect of anti-IL-4 monoclonal antibody, rapamycin and interferon-γ on airway hyperreactivity to acetylcholine in mice
-
Nagai, H., Maeda, Y., Tanaka, H. (1997) Effect of anti-IL-4 monoclonal antibody, rapamycin and interferon-γ on airway hyperreactivity to acetylcholine in mice. Clin. Exp. Allergy 27: 218-224
-
(1997)
Clin. Exp. Allergy
, vol.27
, pp. 218-224
-
-
Nagai, H.1
Maeda, Y.2
Tanaka, H.3
-
25
-
-
0000719679
-
Equivalence of adding zafirlukast versus double-dose inhaled corticosteroids in asthmatic patients symptomatic on low dose inhaled corticosteroids
-
Nayak, A. S., Anderson, P., Kharous, B. L., Williams, K., Simonson, S. (1998) Equivalence of adding zafirlukast versus double-dose inhaled corticosteroids in asthmatic patients symptomatic on low dose inhaled corticosteroids. J. Allergy Clin. Immunol. 101: S333
-
(1998)
J. Allergy Clin. Immunol.
, vol.101
-
-
Nayak, A.S.1
Anderson, P.2
Kharous, B.L.3
Williams, K.4
Simonson, S.5
-
26
-
-
84907113390
-
The effect of methotrexate on in vitro immunoglobulin production
-
O'Meara, A. M., Brazil, J., Reen, D. J. (1985) The effect of methotrexate on in vitro immunoglobulin production. J. Immunopharmacol. 7: 235-245
-
(1985)
J. Immunopharmacol.
, vol.7
, pp. 235-245
-
-
O'Meara, A.M.1
Brazil, J.2
Reen, D.J.3
-
27
-
-
0030764645
-
A comparison of the efficacy and safety of inhaled corticosteroids in asthma
-
Pedersen, S., O'Byrne, P. (1997) A comparison of the efficacy and safety of inhaled corticosteroids in asthma. Allergy 52: 1-34
-
(1997)
Allergy
, vol.52
, pp. 1-34
-
-
Pedersen, S.1
O'Byrne, P.2
-
28
-
-
0026576192
-
Clinical liver disease in patients with rheumatoid arthritis taking methotrexate
-
Phillips, C. A., Cera, P. J., Mangan, T. F., Newman, E. D. (1992) Clinical liver disease in patients with rheumatoid arthritis taking methotrexate. J. Rheumatol. 19: 229-233
-
(1992)
J. Rheumatol.
, vol.19
, pp. 229-233
-
-
Phillips, C.A.1
Cera, P.J.2
Mangan, T.F.3
Newman, E.D.4
-
29
-
-
0036311848
-
Immunoglobulin levels in methotrexate treated paediatric rheumatology patients
-
Rackham, O. J., Sills, J. A., Davidson, J. E. (2002) Immunoglobulin levels in methotrexate treated paediatric rheumatology patients. Arch. Dis. Child. 87: 147-148
-
(2002)
Arch. Dis. Child.
, vol.87
, pp. 147-148
-
-
Rackham, O.J.1
Sills, J.A.2
Davidson, J.E.3
-
30
-
-
0032090373
-
Methotrexate inhibition of inducible nitric oxide synthase in murine lung epithelial cells in vitro
-
Robbins, R. A., Jinkins, P. A., Bryan, T. W., Prado, S. C., Milligan, S. A. (1998) Methotrexate inhibition of inducible nitric oxide synthase in murine lung epithelial cells in vitro. Am. J. Respir. Cell. Mol. Biol. 18: 853-859
-
(1998)
Am. J. Respir. Cell. Mol. Biol.
, vol.18
, pp. 853-859
-
-
Robbins, R.A.1
Jinkins, P.A.2
Bryan, T.W.3
Prado, S.C.4
Milligan, S.A.5
-
31
-
-
0023489896
-
Comparative effects on the immune system of methotrexate and trimetrexate
-
Rosenthal, G. J., Germolec, D. R., Lamm, K. R., Ackermann, M. F., Luster, M. I. (1987) Comparative effects on the immune system of methotrexate and trimetrexate. Int. J. Immunopharmacol. 9: 793-801
-
(1987)
Int. J. Immunopharmacol.
, vol.9
, pp. 793-801
-
-
Rosenthal, G.J.1
Germolec, D.R.2
Lamm, K.R.3
Ackermann, M.F.4
Luster, M.I.5
-
32
-
-
0026051430
-
Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children
-
Sears, M. R., Burrows, B., Flannery, E. M., Herbison, G. P., Hewitt, C. J., Holdaway, M. D. (1991) Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N. Engl. J. Med. 325: 1067-1071
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 1067-1071
-
-
Sears, M.R.1
Burrows, B.2
Flannery, E.M.3
Herbison, G.P.4
Hewitt, C.J.5
Holdaway, M.D.6
-
33
-
-
0030426661
-
Type II collagen-induced arthritis in the diabetic-resistant biobreeding rat: Inflammatory and histopathological features of joint pathology and effects of antiinflammatory and antirheumatic drugs on this chronic arthritic process
-
Smith, R. J., Sly, L. M. (1996) Type II collagen-induced arthritis in the diabetic-resistant biobreeding rat: inflammatory and histopathological features of joint pathology and effects of antiinflammatory and antirheumatic drugs on this chronic arthritic process. J. Pharmacol. Exp. Ther. 277: 1801-1813
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 1801-1813
-
-
Smith, R.J.1
Sly, L.M.2
-
34
-
-
0027491297
-
One year treatment with low dose methotrexate in rheumatoid arthritis: Effect on class specific rheumatoid factors
-
Spadaro, A., Riccieri, V., Scavalli, A., Taccari, E., Zoppini, A. (1993) One year treatment with low dose methotrexate in rheumatoid arthritis: effect on class specific rheumatoid factors. Clin. Rheumatol. 12: 357-360
-
(1993)
Clin. Rheumatol.
, vol.12
, pp. 357-360
-
-
Spadaro, A.1
Riccieri, V.2
Scavalli, A.3
Taccari, E.4
Zoppini, A.5
-
35
-
-
0026695292
-
Acute and chronic suppression of leukotriene B4 synthesis ex vivo in neutrophils from patients with rheumatoid arthritis beginning treatment with methotrexate
-
Sperling, R. I., Benincaso, A. I., Anderson, R. J., Coblyn, J. S., Austen, K. F., Weinblatt, M. E. (1992) Acute and chronic suppression of leukotriene B4 synthesis ex vivo in neutrophils from patients with rheumatoid arthritis beginning treatment with methotrexate. Arthritis Rheum. 35: 376-384
-
(1992)
Arthritis Rheum.
, vol.35
, pp. 376-384
-
-
Sperling, R.I.1
Benincaso, A.I.2
Anderson, R.J.3
Coblyn, J.S.4
Austen, K.F.5
Weinblatt, M.E.6
-
36
-
-
0028109029
-
Comparison of oral pulse methotrexate with placebo in the treatment of severe glucocorticosteroid-dependent asthma
-
Stewart, G. E., Diaz, J. D., Lockey, R. F., Seleznick, M. J., Trudeau, W. L., Ledford, D. K. (1994) Comparison of oral pulse methotrexate with placebo in the treatment of severe glucocorticosteroid-dependent asthma. J. Allergy Clin. Immunol. 94: 482-489
-
(1994)
J. Allergy Clin. Immunol.
, vol.94
, pp. 482-489
-
-
Stewart, G.E.1
Diaz, J.D.2
Lockey, R.F.3
Seleznick, M.J.4
Trudeau, W.L.5
Ledford, D.K.6
-
37
-
-
0031459583
-
Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs
-
Takeda, H., Kogame, A., Tanaka, H., Nagai, H. (1997) Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs. Prostaglandins 54: 805-820
-
(1997)
Prostaglandins
, vol.54
, pp. 805-820
-
-
Takeda, H.1
Kogame, A.2
Tanaka, H.3
Nagai, H.4
-
38
-
-
0037496813
-
Effect of anti-IL-4 and anti-IL-5 antibodies on allergic airway hyperresponsiveness in mice
-
Tanaka, H., Nagai, H., Maeda, Y. (1998) Effect of anti-IL-4 and anti-IL-5 antibodies on allergic airway hyperresponsiveness in mice. Life Sci. 62: PL169-P174
-
(1998)
Life Sci.
, vol.62
-
-
Tanaka, H.1
Nagai, H.2
Maeda, Y.3
-
39
-
-
0021628815
-
Decreased airway responsiveness to histamine in gold salt-treated guinea pigs
-
Yamauchi, N., Suko, M., Morita, Y., Suzuki, S., Ito, K., Miyamoto, T. (1984) Decreased airway responsiveness to histamine in gold salt-treated guinea pigs. J. Allergy Clin. Immunol. 74: 802-807
-
(1984)
J. Allergy Clin. Immunol.
, vol.74
, pp. 802-807
-
-
Yamauchi, N.1
Suko, M.2
Morita, Y.3
Suzuki, S.4
Ito, K.5
Miyamoto, T.6
-
40
-
-
0022221484
-
Toxicity of low dose methotrexate in rheumatoid arthritis
-
Weinblatt, M. E. (1985) Toxicity of low dose methotrexate in rheumatoid arthritis. J. Rheumatol. 12: 35-39
-
(1985)
J. Rheumatol.
, vol.12
, pp. 35-39
-
-
Weinblatt, M.E.1
-
41
-
-
0025305330
-
Longterm experience with low dose weekly methotrexate in rheumatoid arthritis
-
Weinblatt, M. E., Maier, A. L. (1990) Longterm experience with low dose weekly methotrexate in rheumatoid arthritis. J. Rheumatol. 22: 33-38
-
(1990)
J. Rheumatol.
, vol.22
, pp. 33-38
-
-
Weinblatt, M.E.1
Maier, A.L.2
-
42
-
-
0029880013
-
Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids
-
Woolcock, A., Lundback, B., Ringdal, N., Jacques, L. A. (1996) Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am. J. Respir. Crit. Care Med. 153: 1481-1488
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.153
, pp. 1481-1488
-
-
Woolcock, A.1
Lundback, B.2
Ringdal, N.3
Jacques, L.A.4
|