Biodegradation of amino-acid-based poly(ester amide)s: In vitro weight loss and preliminary in vivo studies

Journal of Biomaterials Science, Polymer Edition

Volumn 15, Issue 1, 2004, Pages 1-24

  Tsitlanadze, G ^a   Machaidze, M ^a   Kviria, T ^a   Djavakhishvili, N ^a   Chu, C C ^b   Katsarava, R ^a  

^a GEORGIAN TECHNICAL UNIVERSITY   (Georgia)

^b Department of Molecular Biology and Genetics   (United States)

Author keywords

amino acids; Biodegradation; Enzymes; Hydrolysis; Poly(ester amide); Weight loss

Indexed keywords

ALPHA AMINO ACID; AMIDE; CHYMOTRYPSIN A; DICARBOXYLIC ACID; FATTY ACID; HYDROLASE; POLYESTER; POLYLACTIDE; PROTEINASE; TRIACYLGLYCEROL LIPASE;

ABSORPTION; ADSORPTION; ARTICLE; BIODEGRADATION; CATALYSIS; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME IMMOBILIZATION; ENZYME KINETICS; GRAVIMETRY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; PAPAYA; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ABSORBABLE IMPLANTS; AMINO ACIDS; ANIMALS; BIODEGRADATION, ENVIRONMENTAL; CARICA; CHYMOTRYPSIN; CYSTEINE ENDOPEPTIDASES; DICARBOXYLIC ACIDS; ENZYMES, IMMOBILIZED; GLYCOLS; HYDROLYSIS; HYDROPHOBICITY; IMPLANTS, EXPERIMENTAL; KINETICS; LEUCINE; LIPASE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PHENYLALANINE; POLYESTERS; POTENTIOMETRY; RATS; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUBSTRATE SPECIFICITY; SURFACE PROPERTIES; VISCOSITY;

EID: 1242308388     PISSN: 09205063     EISSN: None     Source Type: Journal    
DOI: 10.1163/156856204322752200     Document Type: Article

References (23)

1. I. Engelberg and J. Kohn, Biomaterials 12, 292 (1991).
2. A. Nathan and J. Kohn, in: Biomedical Polymers: Design-to-Degrade System, S. W. Shalaby (Ed.), Chapter 5, pp. 117-151. Hauser, München (1994).
3. T. Hayashi, Progr. Polym. Sci. 19, 663 (1994).
4. M. Okada, Progr. Polym. Sci. 27, 87 (2002).
5. J. Jagur-Grodzinski, e-Polymer 012 (2003).
6. M. M. Zaalishvili, R. D. Katsarava, S. V. Rogozhin, Y. A. Davidovich, T. M. Kartvelishvili, M. M. Patsuria and D. P. Kharadze, USSR Patent No. 803417 (1980).
7. M. M. Zaalishvili, R. D. Katsarava and T. M. Kartvelishvili, USSR Patent No. 948113 (1981).
8. R. D. Katsarava, T. M. Kartvelishvili, Y. A. Davidovich, M. M. Zaalishvili and S. V. Rogozhin, Dokl. Akad. Nauk SSSR 266, 363 (1982).
9. R. D. Katsarava, T. M. Kartvelishvili and M. M. Zaalishvili, Bull. Acad. Sci. Georgian SSR 113, 533 (1984).
10. R. D. Katsarava, D. P. Kharadze, L. L. Kirmelashvili and M. M. Zaalishvili, Acta Polym. 36, 29 (1985).
11. R. D. Katsarava, D. P. Kharadze, N. Japaridze, L. M. Avalishvili, T. N. Omiadze and M. M. Zaalishvili, Makromol. Chem. 186, 939 (1985).
12. R. D. Katsarava, D. P. Kharadze and N. S. Japaridze, Vysokomol. Soed. Ser. B 28, 518 (1986).
13. R. D. Katsarava, D. P. Kharadze, L. I. Kirmelashvili, N. G. Medzmariashvili, T. A. Goguadze and G. V. Tsitlanadze, Makromol. Chem. 194, 143 (1993).
14. N. Arabuli, G. Tsitlanadze, L. Edilashvili, D. Kharadze, T. Goguadze, V. Beridze, Z. Gomurashvili and R. Katsarava, Macromol. Chem. Phys. 195, 2279 (1994).
15. T. M. Kartvelishvili, A. Kvintradze and R. Katsarava, Macromol. Chem. Phys. 197, 249 (1996).
16. T. Kartvelishvili, G. Tsitlanadze, L. Edilashvili, N. Japaridze and R. Katsarava, Macromol. Chem. Phys. 198, 1921 (1997).
17. R. Katsarava, V. Beridze, N. Arabuli, D. Kharadze, C. C. Chu and C. Y. Won, J. Polym. Sci. Polym. Chem. Edn. 37, 391 (1999).
18. G. Tsitlanadze, T. Kviria, C. C. Chu and R. Katsarava, J. Mater. Sci. Mater. Med. (2003) (in press).
19. C. C. Chu, J. A. von Fraunhofer and H. P. Greisler, Wound Closure Biomaterials & Devices. CRC Press, Boca Raton, FL (1997).
20. R. K. Scopes, Protein Purification: Principles and Practice. Springer, New York, NY (1982).
21. D. Kharadze, T. Omiadze, G. Tsitlanadze, T. Goguadze, N. Arabuli, Z. Gomurashvili and R. Katsarava, Polym. Sci. Ser. A 36, 1214 (1994).
22. K. W. Leong, B. C. Brott and R. Langer, J. Biomed. Mater. Res. 19, 941 (1985).
23. K. Markoishvili, G. Tsitlanadze, R. Katsarava, J. G. Morris and A. Sulakvelidze, Int. J. Dermatol. 41, 453 (2002).