메뉴 건너뛰기




Volumn 5, Issue 2, 2004, Pages 379-387

The effectiveness of secretin in the management of autism

Author keywords

Autism; Efficacy; Measures; Secretin; Subtypes; Trials

Indexed keywords

CENTRAL STIMULANT AGENT; PLACEBO; RG 1068; SECRETIN; SECRETIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 1242296776     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.5.2.379     Document Type: Review
Times cited : (18)

References (53)
  • 1
    • 0033377678 scopus 로고    scopus 로고
    • The screening and diagnosis of autistic spectrum disorders
    • FILIPEK PA, ACCARDO PJ, BARANEK GT et al.: The screening and diagnosis of autistic spectrum disorders. J. Autism Dev. Disord. (1999) 29(6):437-482.
    • (1999) J. Autism Dev. Disord. , vol.29 , Issue.6 , pp. 437-482
    • Filipek, P.A.1    Accardo, P.J.2    Baranek, G.T.3
  • 2
    • 0004235298 scopus 로고
    • AMERICAN PSYCHIATRIC ASSOCIATION (4th edn). Author, Washington, DC
    • AMERICAN PSYCHIATRIC ASSOCIATION: Diagnostic and statistical manual of mental disorders (4th edn). Author, Washington, DC (1994).
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 3
    • 0003055424 scopus 로고    scopus 로고
    • Diagnostic instruments in autism spectrum disorders
    • (2nd edn). Cohen DJ, Volkmar FR (Eds), John Wiley & Sons, Inc., New York
    • LORD C: Diagnostic instruments in autism spectrum disorders. In: Handbook of Autism and Pervasive Developmental Disorders (2nd edn). Cohen DJ, Volkmar FR (Eds), John Wiley & Sons, Inc., New York (1997):460-508.
    • (1997) Handbook of Autism and Pervasive Developmental Disorders , pp. 460-508
    • Lord, C.1
  • 4
    • 0002148785 scopus 로고    scopus 로고
    • Syndromes of autism and atypical development
    • (2nd edn). Cohen DJ, Volkmar FR (Eds), John Wiley & Sons, Inc., New York
    • WING L: Syndromes of autism and atypical development. In: Handbook of Autism and Pervasive Developmental Disorders (2nd edn). Cohen DJ, Volkmar FR (Eds), John Wiley & Sons, Inc., New York (1997 ):148-170.
    • (1997) Handbook of Autism and Pervasive Developmental Disorders , pp. 148-170
    • Wing, L.1
  • 5
    • 0033149456 scopus 로고    scopus 로고
    • Neurodevelopmental processes and psychological functioning in autism
    • GILLBERG C: Neurodevelopmental processes and psychological functioning in autism. Dev. Psychopathol. (1999) 11(3):567-587.
    • (1999) Dev. Psychopathol. , vol.11 , Issue.3 , pp. 567-587
    • Gillberg, C.1
  • 6
    • 0036735751 scopus 로고    scopus 로고
    • The possible role of the cerebellum in autism/PDD: Disruption in a multisensory feedback loop
    • KERN JK: The possible role of the cerebellum in autism/PDD: disruption in a multisensory feedback loop. Med. Hypotheses (2002) 59(3):255-260.
    • (2002) Med. Hypotheses , vol.59 , Issue.3 , pp. 255-260
    • Kern, J.K.1
  • 7
    • 0028934279 scopus 로고
    • New evidence of cerebellar and brain stem hypoplasia in autistic infants, children, and adolescents: The MR imaging study by Hashimoto and colleagues
    • COURCHESNE E: New evidence of cerebellar and brain stem hypoplasia in autistic infants, children, and adolescents: the MR imaging study by Hashimoto and colleagues. J. Autism Dev. Disord. (1995) 25(1):19-22.
    • (1995) J. Autism Dev. Disord. , vol.25 , Issue.1 , pp. 19-22
    • Courchesne, E.1
  • 8
    • 0028906527 scopus 로고
    • DR-positive T cells in autism: Association with decreased plasma levels of the complement C4B protein
    • WARREN RP, YONK J, BURGER RW, ODELL D, WARREN WL: DR-positive T cells in autism: association with decreased plasma levels of the complement C4B protein. Neuropsychobiology (1995) 31(2):53-57.
    • (1995) Neuropsychobiology , vol.31 , Issue.2 , pp. 53-57
    • Warren, R.P.1    Yonk, J.2    Burger, R.W.3    Odell, D.4    Warren, W.L.5
  • 10
    • 0035092562 scopus 로고    scopus 로고
    • Colonic CD8 and γδT-cell infiltration with epithelial damage in children with autism
    • FURLANO RI, ANTHONY A, DAY R et al.: Colonic CD8 and γδT-cell infiltration with epithelial damage in children with autism. J. Pediatrics (2001)138(3):366-372.
    • (2001) J. Pediatrics , vol.138 , Issue.3 , pp. 366-372
    • Furlano, R.I.1    Anthony, A.2    Day, R.3
  • 12
    • 85047685961 scopus 로고    scopus 로고
    • Autism: Evidence of association with adenosine deaminase
    • BOTTINI N, DE KUCA D, SACCUCCI P et al.: Autism: evidence of association with adenosine deaminase. Neurogenetics (2001) 3(2):111-113.
    • (2001) Neurogenetics , vol.3 , Issue.2 , pp. 111-113
    • Bottini, N.1    Dekuca, D.2    Saccucci, P.3
  • 14
    • 0036616924 scopus 로고    scopus 로고
    • Efficacy of porcine secretin in children with autism and pervasive developmental disorder
    • KERN JK, MILLER VS, EVANS PA, TRIVEDI MH: Efficacy of porcine secretin in children with autism and pervasive developmental disorder. J. Autism Dev. Disord. (2002) 32(3):153-160.
    • (2002) J. Autism Dev. Disord. , vol.32 , Issue.3 , pp. 153-160
    • Kern, J.K.1    Miller, V.S.2    Evans, P.A.3    Trivedi, M.H.4
  • 16
    • 0032454027 scopus 로고    scopus 로고
    • Chromosomal disorders and autism
    • GILLBERG C: Chromosomal disorders and autism. J. Autism Dev. Disord. (1998) 28(5):415-425.
    • (1998) J. Autism Dev. Disord. , vol.28 , Issue.5 , pp. 415-425
    • Gillberg, C.1
  • 17
    • 0017360565 scopus 로고
    • Follow-up report on autism in congenital rubella
    • CHESS S: Follow-up report on autism in congenital rubella. J. Autism Dev. Disord. (1977) 7:68-81.
    • (1977) J. Autism Dev. Disord. , vol.7 , pp. 68-81
    • Chess, S.1
  • 18
    • 0023683047 scopus 로고
    • First report of a Canadian epidemiological study of autistic syndromes
    • BRYSON SE, CLARK BS, SMITH IM: First report of a Canadian epidemiological study of autistic syndromes. J. Child Psychol. Psychiatry (1988) 29:433-446.
    • (1988) J. Child Psychol. Psychiatry , vol.29 , pp. 433-446
    • Bryson, S.E.1    Clark, B.S.2    Smith, I.M.3
  • 19
    • 0024509871 scopus 로고
    • The prevalence of autism in Nagoya, Japan: A total population study
    • SUGIYAMA T, ABE T: The prevalence of autism in Nagoya, Japan: a total population study. J. Autism Dev. Disord. (1989) 19:87-96.
    • (1989) J. Autism Dev. Disord. , vol.19 , pp. 87-96
    • Sugiyama, T.1    Abe, T.2
  • 20
    • 0018740511 scopus 로고
    • Severe impairments of social interaction and associated abnormalities in children: Epidemiological and classification
    • WING L, GOULD J: Severe impairments of social interaction and associated abnormalities in children: epidemiological and classification. J. Autism Dev. Disord. (1979) 9:11-29.
    • (1979) J. Autism Dev. Disord. , vol.9 , pp. 11-29
    • Wing, L.1    Gould, J.2
  • 21
    • 1242303466 scopus 로고    scopus 로고
    • Screening a large population of 18 months olds with the CHAT
    • Paper presented at the Proceedings of the Society for Research on Child Development, Albuquerque, USA
    • BAIRD G, CHARMAN T, BARON-COHEN S et al.: Screening a large population of 18 months olds with the CHAT. Paper presented at the Proceedings of the Society for Research on Child Development, Albuquerque, USA (1999).
    • (1999)
    • Baird, G.1    Charman, T.2    Baron-Cohen, S.3
  • 27
    • 0035512171 scopus 로고    scopus 로고
    • Effects of intravenous secretin on language and behavior of children with autism and gastrointestinal symptoms: A single-blinded, open-label pilot study
    • LIGHTDALE JR, HAYER C, DUER A et al.: Effects of intravenous secretin on language and behavior of children with autism and gastrointestinal symptoms: a single-blinded, open-label pilot study. Pediatrics (2001) 108(5):E90.
    • (2001) Pediatrics , vol.108 , Issue.5
    • Lightdale, J.R.1    Hayer, C.2    Duer, A.3
  • 31
    • 0036996270 scopus 로고    scopus 로고
    • The human secretin gene: Fine structure in 11p15.5 and sequence variation in patients with autism
    • YAMAGATA T, ARADHYA S, MORI M, INOUE K, MOMOI MY, NELSON DL: The human secretin gene: fine structure in 11p15.5 and sequence variation in patients with autism. Genomics (2002) 80(2):185-194.
    • (2002) Genomics , vol.80 , Issue.2 , pp. 185-194
    • Yamagata, T.1    Aradhya, S.2    Mori, M.3    Inoue, K.4    Momoi, M.Y.5    Nelson, D.L.6
  • 32
    • 0017723161 scopus 로고
    • Effect of secretin in plasma motilin in man
    • MITZNEGG P, BLOOM SR, DOMSCHKE W et al.: Effect of secretin in plasma motilin in man. Gut (1977) 18:468-471.
    • (1977) Gut , vol.18 , pp. 468-471
    • Mitznegg, P.1    Bloom, S.R.2    Domschke, W.3
  • 34
    • 0036721070 scopus 로고    scopus 로고
    • Differential transport of a secretin analog across the blood-brain and blood-cerebrospinal flud barriers of the mouse
    • BANKS WA, GOULET M, RUSCHE JR, NIEHOFF ML, BOISMENU R: Differential transport of a secretin analog across the blood-brain and blood-cerebrospinal flud barriers of the mouse. J. Pharmacol. Exp. Ther. (2002) 302(3):1062-1069.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , Issue.3 , pp. 1062-1069
    • Banks, W.A.1    Goulet, M.2    Rusche, J.R.3    Niehoff, M.L.4    Boismenu, R.5
  • 36
    • 0035884769 scopus 로고    scopus 로고
    • Secretin facilitates GABA transmission in the cerebellum
    • YUNG WH, LEUNG PS, NG SSM et al.: Secretin facilitates GABA transmission in the cerebellum. J. Neurosci. (2001) 21(18):7063-7068.
    • (2001) J. Neurosci. , vol.21 , Issue.18 , pp. 7063-7068
    • Yung, W.H.1    Leung, P.S.2    Ng, S.S.M.3
  • 37
    • 0030967504 scopus 로고    scopus 로고
    • Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism
    • COURCHESNE E: Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism. Curr. Opin. Neurobiol. (1997) 7:269-278.
    • (1997) Curr. Opin. Neurobiol. , vol.7 , pp. 269-278
    • Courchesne, E.1
  • 38
    • 0034049064 scopus 로고    scopus 로고
    • The cerebellum contributes to higher functions during development: Evidence from a series of children surgically treated for posterior fossa tumors
    • RIVA D, GIORGI C: The cerebellum contributes to higher functions during development: evidence from a series of children surgically treated for posterior fossa tumors. Brain (2000) 123:1051-1061.
    • (2000) Brain , vol.123 , pp. 1051-1061
    • Riva, D.1    Giorgi, C.2
  • 39
    • 0037111283 scopus 로고    scopus 로고
    • What may be the anatomical basis that secretin can improve the mental functions in autism?
    • 15
    • KOVES K, KAUSZ M, RESER D, HORVATH K: What may be the anatomical basis that secretin can improve the mental functions in autism? Regul. Pept. (2002) 15;109(1-3):167-72.
    • (2002) Regul. Pept. , vol.109 , Issue.1-3 , pp. 167-172
    • Koves, K.1    Kausz, M.2    Reser, D.3    Horvath, K.4
  • 41
    • 0033540022 scopus 로고    scopus 로고
    • Lack of benefit of a single dose of synthetic human secretin in the treatment of autism and pervasive developmental disorder
    • SANDLER AD, SUTTON KA, DEWEESE J, GIRARDI MA, SHEPARD V, BODFISH JW: Lack of benefit of a single dose of synthetic human secretin in the treatment of autism and pervasive developmental disorder. N. Engl. J. Med. (1999) 341(24):1801-1806.
    • (1999) N. Engl. J. Med. , vol.341 , Issue.24 , pp. 1801-1806
    • Sandler, A.D.1    Sutton, K.A.2    Deweese, J.3    Girardi, M.A.4    Shepard, V.5    Bodfish, J.W.6
  • 42
    • 0343294374 scopus 로고    scopus 로고
    • Secretin and autism: A two part clinical investigation
    • CHEZ MG, BUCHANAN CP, BAGAN BT et al.: Secretin and autism: a two part clinical investigation. J. Autism Dev. Disord. (2000) 30:87-94.
    • (2000) J. Autism Dev. Disord. , vol.30 , pp. 87-94
    • Chez, M.G.1    Buchanan, C.P.2    Bagan, B.T.3
  • 43
    • 0034534464 scopus 로고    scopus 로고
    • Effect of secretin on childten with autism: A randomized controlled trial
    • DUNN-GEIER J, HO HH, AUESPERG E et al.: Effect of secretin on childten with autism: a randomized controlled trial. Dev. Med. Child Neurol. (2000) 42:796-802.
    • (2000) Dev. Med. Child Neurol. , vol.42 , pp. 796-802
    • Dunn-Geier, J.1    Ho, H.H.2    Auesperg, E.3
  • 44
    • 0035014108 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of single-dose intravenous secretin treatment for children with autism
    • CONIGLIO SJ, LEWIS JD, LANG C et al.: A randomized, double-blind, placebo-controlled trial of single-dose intravenous secretin treatment for children with autism. J. Pediatr. (2001) 138:649-655.
    • (2001) J. Pediatr. , vol.138 , pp. 649-655
    • Coniglio, S.J.1    Lewis, J.D.2    Lang, C.3
  • 45
    • 0034956401 scopus 로고    scopus 로고
    • Transdermal secretin for autism- A case report
    • LAMSON DW, PLAZA SM: Transdermal secretin for autism- a case report. Altern. Med. Rev. (2001) 6:311-313.
    • (2001) Altern. Med. Rev. , vol.6 , pp. 311-313
    • Lamson, D.W.1    Plaza, S.M.2
  • 46
    • 0035347590 scopus 로고    scopus 로고
    • Repeated doses of porcine secretin in the treatment of autism: A randomized, placebo-controlled trial
    • ROBERTS W, WEAVER L, BRIAN J et al.: Repeated doses of porcine secretin in the treatment of autism: a randomized, placebo-controlled trial. Pediatrics (2001) 107(5):E71.
    • (2001) Pediatrics , vol.107 , Issue.5
    • Roberts, W.1    Weaver, L.2    Brian, J.3
  • 47
    • 0034961354 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled crossover study investigating the effect of porcine secretin in children with autism
    • CORBETT B, KHAN K, CZAPANSKY-BEILMAN D et al.: A double-blind, placebo-controlled crossover study investigating the effect of porcine secretin in children with autism. Clin. Pediatr. (2001) 40:327-331.
    • (2001) Clin. Pediatr. , vol.40 , pp. 327-331
    • Corbett, B.1    Khan, K.2    Czapansky-Beilman, D.3
  • 48
    • 0036616941 scopus 로고    scopus 로고
    • Double-blind placebo-controlled trial of secretin: Effects on aberrant behavior in children with autism
    • CAREY T, RATLIFF-SCHAUB K, FUNK J, WEINLE C, MYERS M, JENKS J: Double-blind placebo-controlled trial of secretin: effects on aberrant behavior in children with autism. J. Autism Dev. Disord. (2002) 32(3):161-167.
    • (2002) J. Autism Dev. Disord. , vol.32 , Issue.3 , pp. 161-167
    • Carey, T.1    Ratliff-Schaub, K.2    Funk, J.3    Weinle, C.4    Myers, M.5    Jenks, J.6
  • 49
    • 0036831724 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of porcine versus synthetic secretin for reducing symptoms of autism
    • UNIS AS, MUNSON JA, ROGERS SJ et al.: A randomized, double-blind, placebo-controlled trial of porcine versus synthetic secretin for reducing symptoms of autism. J. Am. Acad. Child Adolesc. Psychiatry (2002) 44(11):1315-1321.
    • (2002) J. Am. Acad. Child Adolesc. Psychiatry , vol.44 , Issue.11 , pp. 1315-1321
    • Unis, A.S.1    Munson, J.A.2    Rogers, S.J.3
  • 50
    • 0036275844 scopus 로고    scopus 로고
    • Multiple doses of secretin in the treatment of autism: A controlled study
    • SPONHEIM E, OFTEDAL G, HELVESCHOU SB: Multiple doses of secretin in the treatment of autism: a controlled study. Acta. Paediatr. (2002) 91:540-545.
    • (2002) Acta Paediatr. , vol.91 , pp. 540-545
    • Sponheim, E.1    Oftedal, G.2    Helveschou, S.B.3
  • 51
    • 0037504305 scopus 로고    scopus 로고
    • Lack of benefit of intravenous synthetic human secretin in the treatment of autism
    • MOLLOY CA, MANNING-COURTNEY P, SWAYNE S et al.: Lack of benefit of intravenous synthetic human secretin in the treatment of autism. J. Autism Dev. Disord. (2002) 32(6):545-551.
    • (2002) J. Autism Dev. Disord. , vol.32 , Issue.6 , pp. 545-551
    • Molloy, C.A.1    Manning-Courtney, P.2    Swayne, S.3
  • 52
    • 1242281199 scopus 로고    scopus 로고
    • REPLIGEN CORPORATION: SecreFlo™ Clinical Trials. Repligen Corporation, Building 1, Suite 100, 41 Seyon Street, Waltham, MA 02453
    • REPLIGEN CORPORATION: SecreFlo™ Clinical Trials. Repligen Corporation, Building 1, Suite 100, 41 Seyon Street, Waltham, MA 02453.
  • 53
    • 0041530343 scopus 로고    scopus 로고
    • Children with autistic spectrum disorders. 1: Comparison of placebo and single dose of human synthetic secretin
    • LEVY SE, SOUDERS MC, WRAY J et al.: Children with autistic spectrum disorders. 1: comparison of placebo and single dose of human synthetic secretin. Arch. Dis. Child (2003) 88:731-736.
    • (2003) Arch. Dis. Child , vol.88 , pp. 731-736
    • Levy, S.E.1    Souders, M.C.2    Wray, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.