A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetases

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 5, 2004, Pages 1339-1342

  Yu, Xiang Y ^a   Finn, John ^a   Hill, Jason M ^a   Wang, Zhong G ^a   Keith, Dennis ^a   Silverman, Jared ^a   Oliver, N ^a  

^a CUBIST PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; FURAN DERIVATIVE; PHENYLALANINE TRANSFER RNA LIGASE; PHENYLALANINE TRANSFER RNA LIGASE INHIBITOR; PYRROLIDINE DERIVATIVE; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ENZYME INHIBITION; IC 50; NONHUMAN; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 1242293879     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.11.081     Document Type: Article

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