Engineering peroxidase activity in myoglobin: The haem cavity structure and peroxide activation in the T67R/S92D mutant and its derivative reconstituted with protohaemin-L-histidine

Biochemical Journal

Volumn 377, Issue 3, 2004, Pages 717-724

  Roncone, Raffaella ^a   Monzani, Enrico ^a   Murtas, Monica ^a   Battaini, Giuseppe ^a   Pennati, Andrea ^a   Sanangelantoni, Anna Maria ^b   Zuccotti, Simone ^c   Bolognesi, Martino ^c   Casella, Luigi ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

Hydrogen peroxide activation; Myoglobin mutant; NMR spectra; Peroxidase activity; X ray structure

Indexed keywords

BIOCHEMICAL ENGINEERING; CATALYSIS; ENZYMES; ESTERS; HYDROGEN PEROXIDE;

MYOGLOBIN;

BIOCHEMISTRY;

ARGININE; ASPARTIC ACID; AZIDE; CYANIDE; HEME; HISTIDINE DERIVATIVE; HYDROGEN PEROXIDE; IMIDAZOLE; MUTANT PROTEIN; MYOGLOBIN; PEROXIDASE; PHENOL; PROTOHAEMIN HISTIDINE; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; CONFORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME ENGINEERING; HOST; LIGAND BINDING; MOLECULAR INTERACTION; MUTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN INTERACTION; SPERM; WHALE; WILD TYPE;

CETACEA; PHYSETER CATODON;

EID: 1242292278     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj20030863     Document Type: Article

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