Tetrapeptides on N- and C-Terminal Regions of Mastoparan Inhibit Catecholamine Release from Chromaffin Cells by Blocking Nicotinic Acetylcholine Receptor

Cellular and Molecular Neurobiology

Volumn 24, Issue 1, 2004, Pages 37-50

  Monoi, Noriyuki ^a,b,f   Usui, Masaya ^a,c   Takahashi, Shunichi ^a   Ito, Hisashi ^a   Kumakura, Konosuke ^d   Kasai, Hisataka ^e  

^a AOYAMA GAKUIN UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c Brain Sci Life Technol Res Found   (Japan)

^d SOPHIA UNIVERSITY   (Japan)

^e TOKYO METROPOLITAN UNIVERSITY   (Japan)

^f LION CORPORATION   (Japan)

Author keywords

Catecholamine; Chromaffin cells; Mastoparan; Mastoparan fragments; Mastoparan fragment analogs; Nicotinic acetylcholine receptor

Indexed keywords

AMINO ACID DERIVATIVE; CATECHOLAMINE; MASTOPARAN; NICOTINE; NICOTINIC RECEPTOR; POTASSIUM ION; TETRAPEPTIDE; WASP VENOM;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATECHOLAMINE RELEASE; CATTLE; CHROMAFFIN CELL; HYDROPHOBICITY; IC 50; NONHUMAN; PRIORITY JOURNAL;

ADRENAL MEDULLA; AMINO ACIDS; ANIMALS; BINDING SITES; CATECHOLAMINES; CATTLE; CELLS, CULTURED; CHROMAFFIN CELLS; HYDROPHOBICITY; NICOTINIC ANTAGONISTS; PEPTIDE FRAGMENTS; PEPTIDES; POTASSIUM; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NICOTINIC; WASP VENOMS;

ANIMALIA; BOS TAURUS; BOVINAE; VESPIDAE;

EID: 1242276391     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CEMN.0000012723.52742.84     Document Type: Article

References (28)

1. Burgoyne, R. D. (1991). Control of exocytosis in adrenal chromaffin cells. Biochim. Biophys. Acta 1071:174-202.
2. Changeux, J. P., Galzi, J. L., Devillers-Thiery, A., and Bertrand, D. (1992). The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis. Q. Rev. Biophys. 25:395-432.
3. Herrero, C. J., Alés, E., Pintado, A. J., López, M. G., García-Palomero, E., Mahata, S. K., O'Connor, D. T., García, A. G., and Montiel, C. (2002). Modulatory mechanism of the endogenous peptide catestatin on neuronal nicotinic acetylcholine receptors and exocytosis. J. Neurosci. 22:377-388.
4. Higashijima, T., Uzu, S., Nakajima, T., and Miyazawa, T. (1987). Mechanism of histamine-release by mastoparan. In Miyazawa, T. (ed.), Peptide Chemistry 1986, Protein Research Foundation, Osaka, pp. 75-78.
5. Higashijima, T., Uzu, S., Nakajima, T., and Ross, E. M. (1988). Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). J. Biol. Chem. 263:6491-6494.
6. Hirai, Y., Yasuhara, T., Yoshida, H., Nakajima, T., Fujino, M., and Kitada, C. (1979). A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem. Pharm. Bull. (Tokyo) 27:1942-1944.
7. Isobe, K., and Nakai, T. (1992). Mechanism of mastoparan-induced catecholamine release from porcine adrenal medullary cells. In Miyai, K., Kanno, T., and Ishikawa E. (eds.), Progress in Clinical Biochemistry, Elsevier Science, pp. 653-655.
8. Ito, H., Kurita, T., Takahashi, S., Murakami, K., Ando, T., Kumakura, K., and Kasai, H. (2000). Increase in N-terminal hydrophobicity in mastoparan molecule enhanced the original hemolytic and catecholamine releasing activities from chromaffin cells. J. Tokyo Acad. Health Sci. 3:109-117.
9. Kennedy, B. P., Mahata, S. K., O'Connor, D. T., and Ziegler, M. G. (1998). Mechanism of cardiovascular actions of the chromogranin A fragment catestatin in vivo. Peptides 19:1241-1248.
10. 344-358) stimulates release of histamine from rat pleural and peritoneal mast cells. In O'Connor, D. T., and Eiden, L. E. (eds.), The Chromaffin Cell: Annals of the New York Academy of Sciences, Vol. 971, New York Academy of Sciences, New York, pp. 349-351.
11. Kumakura, K., Sasaki, K., Sakurai, T., Ohara-Imaizumi, M., Misonou, H., Nakamura, S., Matsuda, Y., and Nonomura, Y. (1994). Essential role of myosin light chain kinase in the mechanism for MgATP-dependent priming of exocytosis in adrenal chromaffin cells. J. Neurosci. 14:7695-7703.
12. 2-activators, melittin and mastoparan, in rat anterior pituitary cells. Cell. Tissue Res. 243:311-316.
13. 3] mastoparan T enhanced the original catecholamine releasing activity from chromaffin cells. J. Tokyo Acad. Health Sci. 2:133-140.
14. Kuroda, Y., Yoshioka, M., Kumakura, K., Kobayashi, K., and Nakajima, T. (1980). Effects of peptides on the release of catecholamines and adenine nucleotides from cultured adrenal chromaffin cells. Mastoparan-induced release. Proc. Jpn. Acad. B 56:660-664.
15. Livett, B. G., and Marley, P. D. (1993). Noncholinergic control of adrenal catecholamine secretion. J. Anat. 183:277-289.
16. 344-364). Properties and function. Adv. Exp. Med. Biol. 482:263-277.
17. Mahata, S. K., O'Connor, D. T., Mahata, M., Yoo, S. H., Taupenot, L., Wu, H., Gill, B. M., and Parmer, R. J. (1997). Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist. J. Clin. Invest. 100:1623-1633.
18. Mousli, M., Bronner, C., Bueb, J. L., Tschirhart, E., Gies, J. P., and Landry, Y. (1989). Activation of rat peritoneal mast cells by substance P and mastoparan. J. Pharmacol. Exp. Ther. 250:329-335.
19. Mousli, M., Bueb, J. L., Bronner, C., Rouot, B., and Landry, Y. (1990). G protein activation: A receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. Trends Pharmacol. Sci. 11:358-362.
20. O'Connor, D. T., Kailasam, M. T., Kennedy B. P., Ziegler M. G., Yanaihara, N., and Parmer, R. J. (2002). The catecholamine release-inhibitory "Catestatin" region of chromogranin A: Early decline in humans at genetic risk of hypertension. In O'Connor, D. T., and Eiden, L. E. (eds.), The Chromaffin Cell: Annals of the New York Academy of Sciences, Vol. 971, New York Academy of Sciences, New York, pp. 533-535.
21. Owen, P. J., Plevin, R., and Boarder, M. R. (1989). Characterization of bradykinin-stimulated release of noradrenaline from cultured bovine adrenal chromaffin cells. J. Pharmacol. Exp. Ther. 248:1231-1236.
22. Takahashi, S., Matsuzawa, N., Oshima, H., Murakami, K., Ito, M., Kurita, T., Kumakura, K., Ito, H., and Kasai, H. (2002). The structure-function relationship of mastoparan: Loss of the hemolytic activity of mastoparan by substituting lysine with ornithine residues in the molecule. J. Tokyo Acad Health Sci. 5:86-96.
23. Tsigelny, I., Mahata, S. K., Taupenot, L., Preece, N. E., Mahata, M., Khan, I., Parmer, R. J., and O'Connor, D. T. (1998). Mechanism of action of chromogranin A on catecholamine release: Molecular modeling of the catestatin region reveals a β-strand/loop/β-strand structure secured by hydrophobic interactions and predictive of activity. Regul. Pept. 77:43-53.
24. Unwin, N. (1995). Acetylcholine receptor channel imaged in the open state. Nature 373:37-43.
25. o. J. Biol. Chem. 268:14715-14723.
26. Wilson, S. P. (1989). Effects of mastoparan on catecholamine release from chromaffin cells. FEBS Lett. 247:239-241.
27. Yamada, K., Matsuo, Y., and Kumakura, K. (1989). Effects of histamine on the catecholamine release from cultured bovine adrenomedullary cells. Therapeutic Res. 10:577-581.
28. Yokokawa, N., Komatsu, M., Takeda, T., Aizawa, T., and Yamada, T. (1989). Mastoparan, a wasp venom, stimulates insulin release by pancreatic islets through pertussis toxin sensitive GTP-binding protein. Biochem. Biophys. Res. Commun. 158:712-716.