Increased microvascular network in bone marrow of HIV-positive haemophilic patients

HIV Medicine

Volumn 5, Issue 1, 2004, Pages 18-25

  Patsouris, E ^a   Katsarou, O ^b   Korkolopoulou, P ^a   Kotsi, P ^b   Kouramba, A ^b   Androulaki, A ^b   Karafoulidou, A ^b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b LAIKO GENERAL HOSPITAL   (Greece)

Author keywords

Bone marrow angiogenesis; CD34 positive microvessels; HIV infection; Myelodysplasia

Indexed keywords

ANTIRETROVIRUS AGENT; CD34 ANTIGEN; CD4 ANTIGEN; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ANGIOGENESIS; ARTICLE; BONE MARROW BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; HEMOPHILIA; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOHISTOCHEMISTRY; MALE; MICROVASCULARIZATION; MYELODYSPLASTIC SYNDROME; PATHOGENESIS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADULT; BONE MARROW; FEMALE; HEMOPHILIA A; HIV INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROCIRCULATION; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; NEOVASCULARIZATION, PATHOLOGIC;

EID: 1242273814     PISSN: 14642662     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2004.00180.x     Document Type: Article

References (60)

1. Perez-Atayde AR, Sallan SE, Tedrow U, Connors S, Allred E, Follaman J. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. Am J Pathol 1997; 150: 815-821.
2. Hussong JW, Rodgers GM, Shami PJ. Evidence of increased angiogenesis in patients with acute myeloid leukemia. Blood 2000; 95: 309-313.
3. Padro I, Ruiz S, Bicker R et al. Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia. Blood 2000; 95: 2637-2644.
4. De Bont E, Rosati S, Jacobs S, Kamps W, Vellenga E. Increased bone marrow vascularisation in patients with acute myeloid leukemia: a possible role for vascular endothelial growth factor. Br J Haematol 2001; 113: 296-304.
5. Aguayo A, Kantargian H, Talpaz M. Increased angiogenesis in chronic myeloid leukemia and myelodysplastic syndromes (Abstract). Blood 1998; 92: 607.
6. Vacca A, Ribatti D, Presta M et al. Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase 2 secretion parallel progression of human multiple myeloma. Blood 1999; 93: 3064-3073.
7. Kay N, Jelinek D, Peterson LA. Angiogenesis in B-chronic lymphocytic leukemia. Leukemia Res 2001; 25: 485-486.
8. Mesa R, Hanson C, Rajkumar V, Schroeder G, Tefferi A. Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia. Blood 2000; 96: 3374-3380.
9. Vacca A, Ribatti D, Roucalli L et al. Bone marrow angiogenesis and progression in multiple myeloma. Br J Harmatol 1994; 87: 503-508.
10. Vacca A, Di Loreto M, Ribatti D et al. Bone marrow of patients with active multiple myeloma angiogenesis and plasma cell adhesion molecules LFA-1, VLA-4, LAM-1 and CD44. Am J Hematol 1995; 50: 9-14.
11. Rajkumar V, Leong T, Roche P et al. Prognostic value of bone marrow angiogenesis in multiple myeloma. Clin Cancer Res 2000; 6: 3111-3116.
12. Ribatti D, Vacca A, Nico B, Fanelli M, Roucalli L, Dammaco F. Angiogenesis spectrum in the stroma of B-cell non Hodgkin's lymphomas. An immumohistochemical and structural study. Eur J Hematol 1996; 56: 45-53.
13. Kini AR, Kay NE, Peterran LA. Increased bone marrow angiogenesis in B cell chronic lymphocytic leukemia. Leukemia 2000; 14: 1414-1418.
14. Aguayo A, O'Brien S, Keating M et al. Clinical relevance of intracellular vascular endothelial growth factor levels in B-cell chronic lymphocytic leukemia. Blood 2000; 96: 768-770.
15. Pruneri G, Bertolini F, Saligo D et al. Angiogenesis in myelodysplastic syndromes. Br J Cancer 1999; 81: 1398-1401.
16. Korkolopoulou P, Apostalidou E, Pavlopoulos P et al. Prognostic evaluation of the microvascular network in myelodysplastic syndromes. Leukemia 2001; 15: 1369-1376.
17. Clatch R, Krigman H, Peters M, Zutter M. Dysplastic haemopoiesis following orthotopic liver transplantation. Comparison with similar changes in HIV infection and primary myelodysplasia. Br J Hematol 1994; 88: 685-692.
18. Thiele J, Zirbes T, Bertsch HP, Titius R, Lorenzen J, Fischer R. AIDS-related bone marrow lesions - myelodysplastic features or predominant inflammatory reactive changes (HIV-myelopathy)? A comparative morphometric study by immunohistochemistry with special emphasis on apoptosis and PCNA-labeling. Anal Cell Pathol 1996; 11: 141-157.
19. Karcher D, Frost A. The bone marrow in human immunodeficiency virus (HIV)-related diseases. Morphology and clinical correlation. Am J Clin Pathol 1991; 95: 63-71.
20. Thiele J, Zirbes T, Wiemers P, Lorenzen J, Kvasnicha H, Fischer R. Incidence of apoptosis in HIV-myelopathy, myelodysplastic syndromes and non specific inflammatory lesions of the bone marrow. Histopathology 1997; 30: 307-311.
21. Katsarou O, Terpos E, Patsouris E et al. Myelodysplastic features in patients with long-term HIV infection and haemophilia. Hemophilia 2001; 7: 47-52.
22. Centers for Disease Control, US Department of Health and Human Services. Classification system for human T-lymphotropic virus type III/lymphadenopathy- associated virus infections. Ann Intern Med 1986; 105: 234-237.
23. Harris NL, Jaffe ES, Diebold I et al. The World Health Organization Classification of Haematological Malignancies: Report of the Clinical Advisory Committee Meeting. Airlie House, VA. J. Clin Oncol 1997; 17: 3835-3899.
24. Sallivan PS, Hanson DL, Chu SY, Jones JL, Ward JVand the Adult/Adolescent Spectrum of Disease Group. Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the Multistate Adult and Adolescent Spectrum of HIV Disease Surveillance Project. Blood 1998; 91: 301-308.
25. Shi SR, Key ME, Kalra K. Antigen retrieval in formulin-fixed, paraffin embedded tissues: an enhancement method for immunohistochemical staining bared on microwave oven heating of tissue sections. J Histochem Cytochem 1991; 39: 741-748.
26. Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J Histochem Cytochem 1981; 29: 577-580.
27. Hanzen S, Grabau D, Rose C, Bak M, Sorensen F. Angiogenesis in breast cancer: a comparative study of the observer variability of methods for determining microvessel density. Lab Invest 1998; 78: 1563-1573.
28. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred E, Moore D. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992; 84: 1875-1887.
29. Mangi M, Newland A. Angiogenesis and angiogenic mediators in hematological malignancies. Br J Hematol 2000; 111: 43-51.
30. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992; 267: 10931-10934.
31. Diaz-Flores L, Gutierrez R, Varel H. Angiogenesis: an update. Histol Histopathol 1994; 9: 807-843.
32. Bussolino F, Albini A, Gamussi G et al. Role of soluble mediators in angiogenesis. Eur J Cancer 1996; 32A: 2401.
33. Ferrara N. Vascular endothelial growth factor. Eur J Cancer 1996; 32A: 2413-2422.
34. Montesano R, Vassali JD, Baird A, Guillemin R, Orci L. Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci USA 1986; 83: 7297-7301.
35. Basilico C, Moscatelli D. The FGF family of growth factors and oncogenes. Adv Cancer Res 1992; 59: 115-165.
36. Aguayo A, Kantarjian H, Manshouri T et al. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood 2000; 96: 2240-2245.
37. Talks K, Harris A. Current status of antiangiogenic factors. Br J Hematol 2000; 109: 477-489.
38. Bruyn P, Breen P, Thomas T. The microcirculation of the bone marrow. Anat Rev 1970; 168: 55-68.
39. Branemark P. Bone marrow microvascular structure and function. Adv Microcirc 1968; 1: 1-65.
40. Fiedler W, Graeven U, Ergun S et al. Vascular endothelial growth factor, a possible paracrine growth factor, in human acute myeloid leukemia. Blood 1997; 89: 1870-1875.
41. Yamaguchi H, Ishii E, Saito S et al. Umbilican vein endothelial cells are an important source of c-kit and stem cell factor which regulate the proliferation of haemopoietic progenitor cells. Br J Haematol 1996; 94: 606-611.
42. Garcia-Monron C, Sanchez-Madrid F, Gardcia-Buey L, Garcia-Arroyo A, Garcia-Sanchez A, Moreno-Otero O. Vascular adhesion molecule expression in viral chronic hepatitis - evidence of neoangiogenesis in portal tracts. Gastroenterology 1995; 108: 231-241.
43. Korkolopoulou P, Viniou N, Kavantzas N et al. Clinicopathologic correlations of bone marrow angiogenesis in chronic myeloid leukemia. A morphometric study. Leukemia 2003; 17: 89-97.
44. Goulding H, Abdul Rashid NF, Robertson J et al. Assessment of angiogenesis in breast carcinoma: an important factor in prognosis? Hum Pathol 1995; 26: 1196-1200.
45. Heimburg S, Oehler M, Papadopoulos T, Caffier H, Kristen P, Dietl J. Prognostic relevance of the endothelial marker CD34 in ovarian cancer. Anticancer Res 1999; 19: 2527-2529.
46. Vermeulen P, Verhoeven D, Fierens H et al. Microvessel quantification in primary colorectal carcinoma: an immunohistochemical study. Br J Cancer 1995; 71: 340-343.
47. Bellamy W, Richter L, Frutiger Y et al. Vascular endothelial cell growth factor (VEGF) is an autocrine promoter of ALIP and leukemia progenitor formation in myelodysplastic syndromes (MDS) Blood 1999; 94 (Suppl. 1), 389a (Abstract).
48. Treacy M, Lai L, Costello C, Clark A. Peripheral blood and bone marrow abnormalities in patients with HIV related disease. Br J Haematol 1987; 65: 289-299.
49. Inone T, Croukaite E, Hirabayashi Y, Bullis J, Mitsui H, Umemura T. Life time treatment of mice with azidothymidine (AZT) produces myelodysplasia. Leukemia Supplement 1997; 3: 123-127.
50. Spivak J, Bender B, Quinn T. Hematologic abnormalities in the acquired immune deficiency syndrome. Am J Med 1984; 77: 224-228.
51. Schneider D, Picker L. Myelodysplasia in the acquired immune deficiency syndrome. Am J Clin Pathol 1985; 84: 144-152.
52. Scadden D, Zeira M, Worn A et al. Human immunodeficiency virus infection of human bone marrow stromal fibroblasts. Blood 1990; 76: 317-322.
53. Jenhious M, Hanley M, Moreno M, Wieder E, McCune J. Human immunodeficiency virus-1 infection interrupts thymopoiesis and multilineage hematopoiesis in vivo. Blood 1998; 8: 2672-2678.
54. Moses A, Williams S, Heneveld M et al. Human immunodeficiency virus infection of bone marrow endothelium reduces induction of stromal hematopoietic growth factors. Blood 1996; 87: 919-925.
55. Allen TD, Dexter T. The essential cells of the hematopoietic microenvironment. Exp Hematol 1984; 12: 517-521.
56. + hematopoietic progenitors express low levels of CD34, the high affinity receptor for human immunodeficiency virus type 1. Blood 1994; 84: 1896-1905.
57. Chi D, Henry J, Kelly J, Thorpe R, Smith J, Krishnaswamy G. The effects of HIV infection on endothelial function. Endothelium 2000; 7: 223-242.
58. Laurence J, Mitra, D, Steiner S et al. Plasma from patients with idiopathic and human immunodeficiency virus associated thrombotic thrombocytopenia purpura induces apoptosis in microvascular endothelial cells. Blood 1996; 87: 3245-3254.
59. Hymes K, Karpatkin S. Human immunodeficiency virus infection and thrombotic microangiopathy. Sem Hematol 1997; 34: 117-125.
60. Collins T, Read M, Neish A et al. Transcriptional regulation of endothelial cell adhesion molecular NF-Kappa B and cytokine-inducible enhancers. FASEB J 1995; 9: 899-909.