Surgical management of enoxaparin- and/or warfarin-induced massive retroperitoneal bleeding: Report of a case and review of the literature

Southern Medical Journal

Volumn 98, Issue 1, 2005, Pages 104-106

  Topgül, Koray ^a   Uzun, Oǧuz ^b   Anadol, A Ziya ^b   Gök, Ali ^b  

^a ONDOKUZ MAYIS UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b NONE

Author keywords

Enoxaparin; Retroperitoneal hematoma; Surgical treatment

Indexed keywords

ENOXAPARIN; FRESH FROZEN PLASMA; VITAMIN K GROUP; WARFARIN;

ABDOMINAL DISTENSION; ADULT; ANAMNESIS; ANTICOAGULANT THERAPY; BLOOD TRANSFUSION; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; FEVER; FLUID THERAPY; HEMOSTASIS; HOSPITALIZATION; HUMAN; IATROGENIC DISEASE; INTERNATIONAL NORMALIZED RATIO; LAPAROTOMY; LUNG EMBOLISM; MALE; PERCUTANEOUS DRAINAGE; PHYSICAL EXAMINATION; PNEUMOTHORAX; POSTOPERATIVE PERIOD; RETROPERITONEAL ABSCESS; RETROPERITONEAL HEMORRHAGE; REVIEW; TACHYCARDIA; TACHYPNEA;

AGED; ANTICOAGULANTS; ENOXAPARIN; HEMORRHAGE; HUMANS; LAPAROTOMY; MALE; PULMONARY EMBOLISM; RETROPERITONEAL SPACE; WARFARIN;

EID: 12344336405     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.SMJ.0000145306.59008.4E     Document Type: Review

References (19)

1. Bratt G, Tömebohm E, Locker D et al. A human pharmacological study comparing conventional heparin and a low molecular weight heparin fragment. Thromb Haemost 1985;53:208-211.
2. Chiu WS. The syndrome of retroperitoneal hemorrhage and lumbar plexus neuropathy during anticoagulant therapy. South Med J 1976;69:595-599.
3. Houde JP, Steinberg G. Intrahepatic hemorrhage after use of low-molecular-weight heparin for total hip arthroplasty. J Arthroplasty 1999;14:372-374.
4. Noble S, Spencer CM. Enoxaparin: A review of its clinical potential in the management of coronary artery disease. Drugs 1998;56:259-272.
5. Lensing AWA, Prints MH, Davidson BL et al. Treatment of deep venous thrombosis with low-molecular-weight heparins. A meta-analysis. Arch Intern Med 1995;155:601-607.
6. Findik S, Erkan ML, Selcuk MB, et al. Low-molecular-weight heparin versus unfractionated heparin in the treatment of patients with acute pulmonary thromboembolism. Respiration 2002;69(5):440-444.
7. Hyers TM, Agnelli G, Hull RD et al. Antithrombotic therapy for venous thromboembolic disease. Chest 119(Suppl 1):176-193, 2001.
8. Antonelli D, Fares L, Anene CH. Enoxaparin associated with huge abdominal wall hematomas: A report of two cases. Am Surg 200;66:797-800.
9. Kumar PD. Thigh hematoma after femoral venipuncture in a patient treated with low molecular-weight heparin. Arch Intern Med 2001;161:1113-1114.
10. Wysowski DK, Talarico L, Bacsanyi J et al. Spinal and epidural hematoma and low-molecular-weight heparin. New Engl J Med 1998;338:1174-1175.
11. Klein SM, D'Ercole F, Greengras RA et al. Enoxaparin-associated with psoas hematoma and lumbar plexopathy after lumbar plexus block. Anesthesiology 1997;87:1576-1579.
12. Montoya JP, Pokala N, Melde SL. Retroperitoneal hematoma and enoxaparin. Ann Intern Med 1999;131:796-797.
13. Dabney A, Bastani B. Enoxaparin-associated severe retroperitoneal bleeding and abdominal compartment syndrome: A report of two cases. Intensive Care Med 2001;27:1954-1957.
14. Chan-Tack KM. Fatal spontaneous retroperitoneal hematoma secondary to enoxaparin. South Med J 2003;96:58-60.
15. Vaya A, Mira Y, Aznar J et al. Enoxaparin-related fatal spontaneous retroperitoneal hematoma in the elderly. Thromb Res 2003;110:69-71.
16. Melde SL. Enoxaparin induced retroperitoneal hematoma. Ann Pharmacother 2003;37:822-824.
17. Mrug M, Mishra PV, Lusane HC et al. Hemothorax and retroperitoneal hematoma after anticoagulation with enoxaparin. South Med J 2002;95:936-938.
18. Weitz J. Low-molecular-weight heparins. N Engl J Med 1997;337:688-698.
19. Camphell NR, Hull RD, Brant R et al. Aging and heparin-related bleeding. Arch Intern Med 1996;156:857-860.