Calculated DNA damage from Gadolinium Auger electrons and relation to dose distributions in a head phantom

International Journal of Radiation Biology

Volumn 80, Issue 11-12, 2004, Pages 933-940

  Goorley, Tim ^a   Zamenhof, Robert ^b   Nikjoo, Hooshang ^c  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c MRC Radiation/Genome Stability Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GADOLINIUM; IODINE 125;

CALCULATION; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; NEUTRON; NEUTRON CAPTURE THERAPY; PHOTON; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIOISOTOPE DECAY; TUMOR CELL;

BRAIN NEOPLASMS; CELL SURVIVAL; COMPUTER SIMULATION; DNA DAMAGE; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRONS; GADOLINIUM; HEAD; ISOTOPES; MODELS, BIOLOGICAL; NEUTRON CAPTURE THERAPY; RADIATION DOSAGE; RELATIVE BIOLOGICAL EFFECTIVENESS; TREATMENT OUTCOME;

MAMMALIA;

EID: 12344332472     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000400017564     Document Type: Conference Paper

References (30)

1. BERNSTEIN, F. C., KOETTZLE, F. F., WILLIAMS, G. J. B., MEYER, E. F., BRICE, M. D., RODGERS, J. R., KENNARD, O., SHIMANOUCHI, T. and TASUMI, M., 1977, The Protein Databank. A computer based archival file for macromolecular structures. Journal of Molecular Biology, 112, 535-542.
2. BRIESMEISTER, J. F., 1997, MCNP - A General Monte Carlo N Particle Transport Code, LA12625-M, Version 4B ed., Los Alamos National Laboratory, Los Alamos.
3. CALEF, D. F. and DEUTCH, J. M., 1983, Diffusion-controlled reactions. Annual Review of Physical Chemistry, 34, 493-523.
4. CHATTERJEE, A. and HOLLEY, W. R., 1993, Computer simulation of initial events in the biochemical mechanisms of DNA damage. Advances in Radiation Biology, 56, 1-19.
5. - with thymine deravitives - A pulse-radiolysis study with optical and conductance detection. Journal of Physical Chemistry, 94, 8186-8192.
6. DEMONCHY, M., 1997, Modelisation De l'effet primaire des rayonnements sur l'adn dans son environments. Thesis, Paul Sabatier University.
7. DE STASIO, G., CASALBORE, P., PALLINI, R., GILBERT, B., SANITA, F., CIOTTI, M. T., ROSI, G., FESTINESI, A., LAROCCA, L. M., RINELLI, A., PERRET, D., MOGK, D. W., PERFETTI, P., MEHTA, M. P. and MERCANTI, D., 2001, Gadolinium in human Glioblastoma cells for Gadolinium Neutron Capture Therapy. Cancer Research, 61, 4272-4277.
8. EASTHAM, A. M., MARPLES, B., KILTIE, A. E., ORTON, C. J. and WEST, C. M. L., 1999, Fibroblast radiosensitivity measured using the comet DNA-damage assay correlates with clonogenic survival parameters. British Journal of Cancer, 79, 1366-1371.
9. EOUCHI-KASAI, K., MURAKAMI, M., ITSUKAICHI, H., FUKUTSU, K., YATAGAI, F., KANAI, T., OHARA, H. and SATO, K., 1998, Repair of DNA double-strand breaks and cell killing by charged particles. Advances in Space Research, 22, 543-549.
10. FOX, J. C. and MCNALLY, N. J., 1988, Cell survival and DNA double strand break repair following x-ray or neutron irradiation of V79 cells. International Journal of Radiation Biology, 54, 1021-1030.
11. GOORLEY, T. and NIKJOO, H., 2000, Electron and photon spectra for 3 gadolinium therapy approaches. Radiation Research, 154, 556-563.
12. GOORLEY, T., KIGER, W. S. III and ZAMENHOF, R. G., 2002, Reference Dosimetry Calculations for Neutron Capture Therapy with Comparison of Analytical and Voxel Models. Medical Physics, 29, 145-156.
13. JONAH, C. D., HART, E. J., MILLER, J. R. and MATHESON, M. S., 1976, Yield and decay of the hydrated electron from 100 ps to 3ns. Journal of Physical Chemistry, 80, 1267-1270.
14. LOBRICH, M., COOPER, P. K. and RYDBERG, B., 1996, Non-random distribution of DNA double-strand breaks induced by particle irradiation. International Journal of Radiation Biology, 70, 493-503.
15. 157Gd. International Journal of Radiation Biology, 54, 205-8.
16. MAKI, H., SAITO, M., KOBAYSHI, T. and AKABOSHI, M., 1986, Cell inactivation and DNA single and double-strand breaks in cultured mammalian cells irradiated by a thermal neutron beam. International Journal of Radiation Biology, 50, 795-809.
17. MASIAKOWSKI, J. T., HORTON, J. L. and PETERS, L. J., 1992, Gadolinium neutron capture therapy for brain tumors: a computer study. Medical Physics, 19, 1277-84.
18. NEWMAN, H. C., PRISE, K. M., FOLKARD, M. and MICHAEL, B. D., 1997, DNA double-strand break distributions in X-ray and alpha-particle irradiated V79 cells: Evidence for non-random breakage. International Journal of Radiation Biology, 71, 347-363.
19. NIKJOO, H., O'NEILL, P., GOODHEAD, D. T. and TERRISSOL, M. 1997, Computational modelling of low-energy electron induced DNA damage by early physical and chemical events. International Journal of Radiation Biology. 71, 467-483.
20. NIKJOO, H., O'NEILL, P., TERRISSOL, M. and GOODHEAD, D. T., 1999, Quantitative modelling of DNA damage using Monte Carlo track structure method. Radiation Environmental Biophysics, 38, 31-38.
21. NIKJOO, H., GOORLEY, T., FULFORD, J., TAKAURA, K. and ITO, T., 2002, Quantitative analysis of the energetics of DNA damage. Radiation Protection Dosimetry, 99, 91-98.
22. PRISE, K. M., FOLKARD, M., NEWMAN, H. C. and MICHAEL, B. D., 1994, Effect of radiation quality on lesion complexity in cellular DNA. International Journal of Radiation Biology, 66, 537-542.
23. ROOTS, R. and OKADA, S., 1975, Estimation of life times and diffusion distances of radicals involved in X-ray induced DNA strand breakage or killing of mammalian cells. Radiation Research, 64, 306-320.
24. ROTHKAMM, K. and LOBRICH, M., 2003, Evidence for a lack of DNA double-stran break repair in human cells exposed to very low x-ray doses. Proceedings of the National Academy of Sciences, 100, 5057-5062.
25. RYDBERG, B., HOLLEY, W. R., MIAN, I. S. and CHATTERJEE, A., 1998, Chromatin conformation in living cells: Support for a zig-zag model of the 30 nm chromatin fiber. Journal of Molecular Biology, 28, 71-84.
26. SCHOLES, G., WILLSON, R. L. and EBERT, M., 1969, Pulse radiolysis of aqueous solutions of deoxyribonucleotides and of DNA: Reaction with hydroxy-radicals. Journal of the Chemical Society D-Chemical Communications, 1, 17-18.
27. SHIH, J. E. and BRUGGER, R. M., 1992, Gadolinium as a neutron capture therapy agent. Medical Physics, 19, 733-44.
28. TERRISSOL, M. and BEAUDRE, A., 1990, Simulation of space and time evolution of radiolytic species induced by electrons in water. Radiation Protection Dosimetry, 31, 171-175.
29. VON SONNTAG, C., 1987, The Chemical Basis of Radiation Biology (London: Taylor & Francis) pp. 117-166, 221-294.
30. ZHAO, Y., SONG, R., WANG, X. and LIU, Y., 1997, A combination of gadolinium and boron compounds for use in Gd-BNCT. In B. Larssons, J. Crawford, and R. Weinreich (eds), Advances in Neutron Capture Therapy (Amsterdam: Elsevier Science), pp. 451-455.