Effect of 3′ UTR length on the translational regulation of 5′-terminal oligopyrimidine mRNAs

Gene

Volumn 344, Issue , 2005, Pages 213-220

  Ledda, Mario ^a   Di Croce, Mara ^a   Bedini, Barbara ^a   Wannenes, Francesca ^a   Corvaro, Marco ^a   Boyl, Pietro Pilo ^a   Caldarola, Sara ^a   Loreni, Fabrizio ^a   Amaldi, Francesco ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

3 Untranslated region; 5 TOP mRNA; Ribosomal protein mRNA; Short 3 UTR; Translational control

Indexed keywords

BETA ACTIN; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PROTEIN S6; ENHANCED GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; OLIGONUCLEOTIDE; PYRIMIDINE NUCLEOTIDE; RIBOSOME PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; CELL ASSAY; CELL GROWTH; CELL STRAIN HEK293; CHIMERA; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYSOME; PRIORITY JOURNAL; REPORTER GENE; SERUM; STARVATION; STOP CODON; TERMINAL OLIGOPYRIMIDINE TRACT; TRANSLATION REGULATION; CELL LINE; GENETICS; METABOLISM; MUTATION; PLASMID; PROTEIN SYNTHESIS;

VERTEBRATA;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; CELL LINE; GREEN FLUORESCENT PROTEINS; HUMANS; MUTATION; OLIGONUCLEOTIDES; PLASMIDS; PROTEIN BIOSYNTHESIS; PYRIMIDINE NUCLEOTIDES; RECOMBINANT FUSION PROTEINS; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEINS; RNA, MESSENGER; TRANSFECTION;

EID: 12344324816     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2004.09.023     Document Type: Article

References (24)

1. F. Amaldi, and P. Pierandrei-Amaldi TOP genes: a translationally controlled class of genes including those coding for ribosomal proteins Prog. Mol. Subcell. Biol. 18 1997 1 17
2. D. Avni, S. Shama, F. Loreni, and O. Meyuhas Vertebrate mRNAs with a 5′-terminal pyrimidine tract are candidates for translational repression in quiescent cells: Characterization of the translational cis-regulatory element Mol. Cell. Biol. 14 1994 3822 3833
3. C. Bagni, P. Mariottini, L. Terrenato, and F. Amaldi Individual variability in the translational regulation of ribosomal protein synthesis in Xenopus Mol. Gen. Genet. 234 1992 60 64
4. A.W.B. Craig, A. Haghighat, A.T. Yu, and N. Sonenberg Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation Nature 392 1998 520 523
5. C. Crosio, P. Pilo-Boyl, F. Loreni, P. Pierandrei-Amaldi, and F. Amaldi La protein has a positive effect on the translation of TOP mRNAs in vivo Nucleic Acids Res. 28 2000 2927 2934
6. E.A. Grzybowska, A. Wilczynska, and J.A. Siedlecki Regulatory functions of 3′UTRs Biochem. Biophys. Res. Commun. 288 2001 291 295
7. A. Kahvejian, G. Roy, and N. Sonenberg The mRNA closed-loop model: the function of PABP and PABP-interacting proteins in mRNA translation Cold Spring Harbor Symp. Quant. Biol. 66 2001 293 300
8. P.A. Krieg A Laboratory Guide to RNA: Isolation, analysis and synthesis 1996 Wiley-Liss New York
9. H. Le, K.S. Browning, and D.R. Gallie The phosphorylation state of poly(A)-binding protein specifies its binding to poly(A) RNA and its interaction with eukaryotic initiation factor (eIF) 4F, eIFiso4F, and eIF4B J. Biol. Chem. 275 2000 17452 17462
10. S. Levy, D. Avni, N. Hariharan, R.P. Perry, and O. Meyuhas Oligopyrimidine tract at the 5′ end of mammalian ribosomal protein mRNAs is required for their translational control Proc. Natl. Acad. Sci. U. S. A. 88 1991 3319 3323
11. P. Mariottini, and F. Amaldi The 5′ untranslated region of mRNA for ribosomal protein S19 is involved in its translational regulation during Xenopus development Mol. Cell. Biol. 10 1990 816 822
12. O. Meyuhas, and E. Hornstein Translational control of TOP mRNAs N. Sonenberg J.W.B. Hershey M.B. Mathews Translational Control of Gene Expression 2000 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 671 693
13. O. Meyuhas, B. Yael, P. Pierandrei-Amaldi, and F. Amaldi Analysis of polysomal RNA P.A. Krieg A Laboratory Guide to RNA: Isolation, Analysis and Synthesis 1996 Wiley-Liss New York 65 81
14. Y.M. Michel, A.M. Borman, S. Paulous, and K.M. Kean Eukaryotic initiation factor 4G-poly(A) binding protein interaction is required for poly(A) tail-mediated stimulation of picornavirus internal ribosome entry segment-driven translation but not for X-mediated stimulation of hepatitis C virus translation Mol. Cell. Biol. 21 2001 4097 4109
15. F. Mignone, C. Gissi, S. Liuni, and G. Pesole Untranslated regions of mRNAs Genome Biol. 3 2002 Electronic publication REVIEWS0004
16. L. Pellizzoni, B. Cardinali, N. Lin-Marq, D. Mercanti, and P. Pierandrei-Amaldi A Xenopus laevis homologue of the La autoantigen binds the pyrimidine tract of the 5′UTR of ribosomal protein mRNAs in vitro: implication of a protein factor in complex formation J. Mol. Biol. 259 1996 904 915
17. L. Pellizzoni, F. Lotti, B. Maras, and P. Pierandrei-Amaldi Cellular nucleic acid binding protein binds a conserved region of the 5′UTR of Xenopus laevis ribosomal protein mRNAs J. Mol. Biol. 267 1997 264 275
18. G. Pesole, S. Liuni, G. Grillo, F. Licciulli, A. Larizza, W. Makalowski, and C. Saccone UTRdb and UTRsite: specialized databases of sequences and functional elements of 5′ and 3′ untranslated regions of eukaryotic mRNAs Nucleic Acids Res. 28 2000 193 196
19. T. Preiss, and M.W. Hentze Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast Nature 392 1998 516 520
20. J. Sambrook, E.F. Fritsch, and T. Maniatis Molecular Cloning: A Laboratory Manual 1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
21. R.L. Tanguay, and D.R. Gallie Translational efficiency is regulated by the length of the 3′ untranslated region Mol. Cell. Biol. 16 1966 146 156
22. M. Wakiyama, H. Imataka, and N. Sonenberg Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation Curr. Biol. 10 2000 1147 1150
23. M. Wickens, P. Anderson, and R. Jackson Life and death in the cytoplasm: messages from the 3′ end Curr. Opin. Genet. Dev. 1997 220 232
24. M. Wigler, E. Sweet, G.K. Sim, B. Wold, A. Pellicer, E. Lacy, T. Maniatis, S. Silverstein, and R. Axel Transformation of mammalian cells with genes from procaryotes and eucaryotes Cell 17 1979 777 785