Receptor-mediated basic fibroblast growth factor signaling regulates cyclic pressure-induced human endothelial cell proliferation

Endothelium: Journal of Endothelial Cell Research

Volumn 11, Issue 5-6, 2004, Pages 285-291

  Shin, Hainsworth Y ^a,b   Schwartz, Eric A ^a,b   Bizios, Rena ^a   Gerritsen, Mary E ^b  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b GENENTECH INC   (United States)

Author keywords

bFGF; Cyclic pressure; Endothelial cell; FGFR; Mechanotransduction

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2; MONOCLONAL ANTIBODY;

ARTICLE; ATTENUATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MECHANOTRANSDUCTION; MOLECULAR DYNAMICS; PRESSURE MEASUREMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANTIBODIES, MONOCLONAL; CELL DIVISION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; HUMANS; PHOSPHORYLATION; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; TYROSINE;

EID: 12344319160     PISSN: 10623329     EISSN: None     Source Type: Journal    
DOI: 10.1080/10623320490904205     Document Type: Article

References (29)

1. Acevedo A.D., Bowser S.S., Gerritsen M.E., and Bizios R. (1993) Morphological and proliferative responses of endothelial cells to hydrostatic pressure: Role of fibroblast growth factor. Journal of Cellular Physiology, 157, 603-614.
2. Chen K.D., Li Y.S., Kim M., Li S., Yuan S., Chien S., and Shyy J.Y. (1999) Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. Journal of Biological Chemistry, 274, 18393-18400.
3. Choi J., Ko M.K., and Kay E.P. (2000) Subcellular localization of the expressed 18 kDa FGF-2 isoform in corneal endothelial cells. Molecular Vision, 6, 222-231.
4. Davies P.F., Barbee K.A., Volin M.V., Robotewskyj A., Chen J., Joseph L., Griem M.L., Wernick M.N., Jacobs E., Polacek D.C., dePaola N., and Barakat A.I. (1997) Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. Annual Reviews in Physiology, 59, 527-549.
5. Friesel R.E., and Maciag T. (1995) Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction. FASEB Journal, 9, 919-925.
6. Hannan, R.L., Kourembanas, S., Flanders, K.C., Rogelj, S.J., Roberts, A.B., Faller, D.V., and Klagsbrun, M. (1988) Endothelial cells synthesize basic fibroblast growth factor and transforming growth factor beta. Growth Factors, 1, 7-17.
7. Jih Y.J., Lien W.H., Tsai W.C., Yang G.W., Li C., and Wu L.W. (2001) Distinct regulation of genes by bFGF and VEGF-A in endothelial cells. Angiogenesis, 4, 313-321.
8. Kato, S., Sasaguri, Y., Azagami, S., Nakano, R., Hamada, T., Arima, N., Tanimoto, A., and Morimatsu, M. (1994) Ambient pressure stimulates immortalized human aortic endothelial cells to increase DNA synthesis and matrix metalloproteinase 1 (tissue collagenase) production. Virchows Archives, 425, 385-390.
9. Klint P., Kanda S., and Claesson-Welsh L. (1995) Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells. Journal of Biological Chemistry, 270, 23337-23344.
10. Laskey W.K., Ferrari V.A., Palevsky H.I., and Kussmaul W.G. (1993) Pulmonary artery hemodynamics in primary pulmonary hypertension. Journal of the American College of Cardiology, 21, 406-412.
11. Maher P.A. (1996) Identification and characterization of a novel, intracellular isoform of fibroblast growth factor receptor-1 (FGFR-1). Journal of Cellular Physiology, 169, 380-390.
12. Malek A.M., Gibbons G.H., Dzau V.J., and Izumo S. (1993) Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium. Journal of Clinical Investigations, 92, 2013-2021.
13. McKeehan W.L., Wang F., and Kan M. (1998) The heparan sulfate-fibroblast growth factor family: Diversity of structure and function. Progress in Nucleic Acid Research and Molecular Biology, 59, 135-176.
14. Mills I., and Sumpio B.E. (1999) Endothelium and cyclic strain. In Mechanical Forces and the Endothelium (ed. P.I. Lelkes . Harwood Academic Publishers, Amsterdam, The Netherlands, pp. 221-275.
15. Ornitz D.M. (2000) FGFs, heparan sulfate and FGFRs: Complex interactions essential for development. Bioessays, 22, 108-112.
16. Pepper M.S., and Mandriota S.J. (1998) Regulation of vascular endothelial growth factor receptor-2 (Flk-1) expression in vascular endothelial cells. Experimental Cell Research, 241, 414-425.
17. Pepper M.S., Mandriota S.J., Jeltsch M., Kumar V, and Alitalo K. (1998) Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellualr proteolytic activity. Journal of Cellular Physiology, 177, 439-452.
18. Raeside D.A., Chalmers G., Clelland J., Madhok R., and Peacock A.J. (1998) Pulmonary artery pressure variation in patients with connective tissue disease: 24 hour ambulatory pulmonary artery pressure monitoring. Thorax, 53, 857-862.
19. Rhoads D.N., Eskin S.G., and McIntire L.V. (2000) Fluid flow releases fibroblast growth factor-2 from human aortic smooth muscle cells. Arterioscelerosis, Thrombosis, and Vascular Biology, 120, 416-421.
20. Schlessinger J. (2001) Cell signaling by receptor tyrosine kinases. Cell, 103, 211-225.
21. Schwartz E.A., Bizios R., Medow M.S., and Gerritsen M.E. (1999) Exposure of human vascular endothelial cells to sustained hydrostatic pressure stimulates proliferation. Involvement of the alpha v integrins. Circulation Research, 84, 315-322.
22. Shin H.Y., Gerritsen M.E., and Bizios R. (2002a) Regulation of endothelial cell proliferation and apoptosis by cyclic pressure. Annals of Biomedical Engineering, 30, 297-304.
23. Shin H.Y., Smith M.L., Toy K.J., Williams P.M., Bizios R., and Gerritsen M.E. (2002b) VEGF-C mediates cyclic pressure-induced endothelial cell proliferation. Physiological Genomics, 11, 245-251.
24. Stachowiak E.K., Maher P.A., Tucholski J., Mordechai E., Joy A., Moffett J., Coons S., and Stachowiak M.K. (1997) Nuclear accumulation of fibroblast growth factor receptors in human glial cells - association with cell proliferation. Oncogene, 14, 2201-2211.
25. Sweeney T.E. (2002) Department of Biology, University of Scranton, Scranton, PA. Personal communication to Dr. Mary Gerritsen.
26. Topper J.N., Cai J., Qiu Y., Anderson K.R., Xu Y.Y., Deeds J.D., Feeley R., Gimeno C.J., Woolf E.A., Tayber O., Mays G.G., Sampson B.A., Schoen F.J., Gimbrone M.A., and Falb D. (1997) Vascular MADs: Two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proceedings of the National Academy of Science of the United States of America, 94, 9314-9319.
27. Traub O., Ishida T., Ishida M., Tupper J.C., and Berk B.C. (1999) Shear stress-mediated extracellular signal-regulated kinase activation is regulated by sodium in endothelial cells. Potential role for a voltage-dependent sodium channel. Journal of Biological Chemistry, 274, 20144-20150.
28. Tuder R.M., Cool C.D., Yeager M., Taraseviciene-Stewart L., Bull T.M., and Voelkel N.F. (2001) The pathobiology of pulmonary hypertension. Endothelium. Clinical Chest Medicine, 22, 405-418.
29. Vouyouka A.G., Powell R.J., Ricotta J., Chen H., Dudrick D.J., Sawmiller C.J., Dudrick S.J., and Sumpio, B.E. (1998) Ambient pulsatile pressure modulates endothelial cell proliferation. Journal of Molecular and Cellular Cardiology, 30, 609-615.