AVP V1b selective antagonist SSR149415 blocks aggressive behaviors in hamsters

Pharmacology Biochemistry and Behavior

Volumn 80, Issue 1, 2005, Pages 189-194

  Blanchard, Robert J ^a   Griebel, Guy ^b   Farrokhi, Catherine ^a   Markham, Chris ^a   Yang, Mu ^a   Blanchard, D Caroline ^c  

^a UNIVERSITY OF HAWAII   (United States)

^b SANOFI   (France)

^c UNIVERSITY OF HAWAII   (United States)

Author keywords

Aggression; Arginine vasopressin; AVP; Defense; Hamster; Resident intruder; SSR149415; V1b antagonist; Vasopressin

Indexed keywords

1 [5 CHLORO 1 (2,4 DIMETHOXYLPHENYLSULFONYL) 2,3 DIHYDRO 3 (2 METHOXYPHENYL) 2 OXO 1H INDOL 3 YL] 4 HYDROXY N,N DIMETHYL 2 PYRROLIDINECARBOXAMIDE; 1 [5 CHLORO 1 [(2,4 DIMETHOXYPHENYL)SULFONYL] 3 (2 METHOXYPHENYL) 2 OXO 2,3 DIHYDRO 1H INDOL 3 YL] 4 HYDROXY N,N DIMETHYL 2 PYRROLIDINE CARBOXAMIDE; ARGIPRESSIN DERIVATIVE; ARGIPRESSIN V1B; HORMONE ANTAGONIST; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; 1 (5 CHLORO 1 ((2,4 DIMETHOXYPHENYL)SULFONYL) 3 (2 METHOXYPHENYL) 2 OXO 2,3 DIHYDRO 1H INDOL 3 YL) 4 HYDROXY N,N DIMETHYL 2 PYRROLIDINECARBOXAMIDE; 1-(5-CHLORO-1-((2,4-DIMETHOXYPHENYL)SULFONYL)-3-(2-METHOXYPHENYL)-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)-4-HYDROXY-N,N-DIMETHYL-2-PYRROLIDINECARBOXAMIDE; ARGIPRESSIN; INDOLE DERIVATIVE; VASOPRESSIN RECEPTOR;

AGGRESSION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; HAMSTER; MALE; NONHUMAN; PRIORITY JOURNAL; SMELLING; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

CRICETINAE; MESOCRICETUS AURATUS;

AGGRESSION; ANIMALS; ARGININE VASOPRESSIN; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; MALE; PYRROLIDINES; RECEPTORS, VASOPRESSIN;

EID: 12344317240     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2004.10.024     Document Type: Article

References (34)

1. G. Aguilera, and C. Rabadan-Diehl Vasopressinergic regulation of the hypothalamic-pituitary-adrenal axis: implications for stress adaptation Regul. Pept. 96 2000 23 29
2. H.E. Albers, and C.F. Ferris Role of the flank gland in vasopressin induced scent marking behavior in the hamster Brain Res. Bull. 17 1986 387 389
3. H.E. Albers, J. Pollock, W.H. Simmons, and C.F. Ferris A V1-like receptor mediates vasopressin-induced flank marking behavior in hamster hypothalamus J. Neurosci. 6 1986 2085 2089
4. M. Bamshad, and H.E. Albers Neural circuitry controlling vasopressin-stimulated scent marking in Syrian hamsters (Mesocricetus auratus) J. Comp. Neurol. 369 1996 252 263
5. M. Bamshad, M. Karom, P. Pallier, and H.E. Albers Role of the central amygdala in social communication in Syrian hamsters (Mesocricetus auratus) Brain Res. 744 1997 15 22
6. R.M. Bluthe, and R. Dantzer Social recognition does not involve vasopressinergic neurotransmission in female rats Brain Res. 535 1990 301 304
7. R.M. Bluthe, and R. Dantzer Role of the vomeronasal system in vasopressinergic modulation of social recognition in rats Brain Res. 604 1993 205 210
8. R.M. Bluthe, J. Schoenen, and R. Dantzer Androgen-dependent vasopressinergic neurons are involved in social recognition in rats Brain Res. 519 1990 150 157
9. E.F. Coccaro, R.J. Kavoussi, R.L. Hauger, T.B. Cooper, and C.F. Ferris Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects Arch. Gen. Psychiatry 55 1998 708 714
10. J.C. Compaan, R.M. Buijs, C.W. Pool, A.J. De Ruiter, and J.M. Koolhaas Differential lateral septal vasopressin innervation in aggressive and nonaggressive male mice Brain Res. Bull. 30 1993 1 6
11. R. Dantzer Vasopressin, gonadal steroids and social recognition Prog. Brain Res. 119 1998 409 414
12. R. Dantzer, G.F. Koob, R.M. Bluthe, and M. Le Moal Septal vasopressin modulates social memory in male rats Brain Res. 457 1988 143 147
13. Y. Delville, K.M. Mansour, and C.F. Ferris Serotonin blocks vasopressin-facilitated offensive aggression: interactions within the ventrolateral hypothalamus of golden hamsters Physiol. Behav. 59 1996 813 816
14. Y. Delville, K.M. Mansour, and C.F. Ferris Testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus Physiol. Behav. 60 1996 25 29
15. M. Engelmann, C.T. Wotjak, I. Neumann, M. Ludwig, and R. Landgraf Behavioral consequences of intracerebral vasopressin and oxytocin: focus on learning and memory Neurosci. Biobehav. Rev. 20 1996 341 358
16. H.G. Everts, A.J. De Ruiter, and J.M. Koolhaas Differential lateral septal vasopressin in wild-type rats: correlation with aggression Horm. Behav. 31 1997 136 144
17. C.F. Ferris Adolescent stress and neural plasticity in hamsters: a vasopressin-serotonin model of inappropriate aggressive behaviour Exp. Physiol. 85 2000 85 90
18. C.F. Ferris, and M. Potegal Vasopressin receptor blockade in the anterior hypothalamus suppresses aggression in hamsters Physiol. Behav. 44 1988 235 239
19. C.F. Ferris, H.E. Albers, S.M. Wesolowski, B.D. Goldman, and S.E. Luman Vasopressin injected into the hypothalamus triggers a stereotypic behavior in golden hamsters Science 224 1984 521 523
20. C.F. Ferris, J. Pollock, H.E. Albers, and S.E. Leeman Inhibition of flank-marking behavior in golden hamsters by microinjection of a vasopressin antagonist into the hypothalamus Neurosci. Lett. 55 1985 239 243
21. C.F. Ferris, D.M. Meenan, J.F. Axelson, and H.E. Albers A vasopressin antagonist can reverse dominant/subordinate behavior in hamsters Physiol. Behav. 38 1986 135 138
22. C.F. Ferris, E.A. Singer, D.M. Meenan, and H.E. Albers Inhibition of vasopressin-stimulated flank marking behavior by V1-receptor antagonists Eur. J. Pharmacol. 154 1988 153 159
23. C.F. Ferris, L. Gold, G.J. De Vries, and M. Potegal Evidence for a functional and anatomical relationship between the lateral septum and the hypothalamus in the control of flank marking behavior in Golden hamsters J. Comp. Neurol. 293 1990 476 485
24. 1) antagonist blocks flank marking and selectively labels neural binding sites in golden hamsters Physiol. Behav. 54 1993 737 747
25. C.F. Ferris, Y. Delville, R.W. Irvin, and M. Potegal Septo-hypothalamic organization of a stereotyped behavior controlled by vasopressin in golden hamsters Physiol. Behav. 55 1994 755 759
26. C.F. Ferris, R.H. Melloni Jr., G. Koppel, K.W. Perry, R.W. Fuller, and Y. Delville Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters J. Neurosci. 17 1997 4331 4340
27. C.F. Ferris, Y. Delville, S. Bonigut, and M.A. Miller Galanin antagonizes vasopressin-stimulated flank marking in male golden hamsters Brain Res. 832 1999 1 6
28. 1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders Proc. Natl. Acad. Sci. 99 2002 6370 6375
29. 1b receptor as a therapeutic target in stress-related disorders Curr. Drug Target CNS Neurol. Disord. 2 2003 191 200
30. A.C. Hennessey, D.C. Whitman, and H.E. Albers Microinjection of arginine-vasopressin into the periaqueductal gray stimulates flank marking in Syrian hamsters (Mesocricetus auratus) Brain Res. 569 1992 136 140
31. M. Le Moal, R. Dantzer, B. Michaud, and G.F. Koob Centrally injected arginine vasopressin (AVP) facilitates social memory in rats Neurosci. Lett. 77 1987 353 359
32. 1b receptor ligands Prog. Brain Res. 139 2002 197 210
33. 1b receptor antagonist J. Pharmacol. Exp. Ther. 300 2002 1122 1130
34. 1b receptor knockout reduces aggressive behavior in male mice Mol. Psychiatry 7 2002 975 984