1,3-Dimethylisoguaninium, an antiangiogenic purine analog from the sponge Amphimedon paraviridis

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 6, 2003, Pages 731-733

  Jeong, Sei Joon ^a   Inagaki, Masanori ^a   Higuchi, Ryuichi ^a   Miyamoto, Tomofumi ^a   Ono, Mayumi ^b   Kuwano, Michihiko ^b   Van Soest, Rob W M ^c  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

1,3 Dimethylisoguaninium; Amphimedon paraviridis; Antiangiogenesis; Marine sponge; Purine analog

Indexed keywords

1,3 DIMETHYLISOGUANINIUM; ANGIOGENESIS INHIBITOR; FIBROBLAST GROWTH FACTOR; GUANINE DERIVATIVE; UNCLASSIFIED DRUG;

AMPHIMEDON PARAVIRIDIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SYNTHESIS; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; SPONGE (PORIFERA); X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

EID: 12344312135     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.731     Document Type: Article

References (6)

1. Jeong S. J., Higuchi R., Miyamoto T., Ono M., Kuwano M., Mawatari S. F., J. Nat. Prod., 65, 1344-1345 (2002).
2. Jeong S. J., Itokawa T., Shibuya M., Kuwano M., Ono M., Higuchi R., Miyamoto T., Cancer Lett., 187, 129-133 (2002).
3. Mitchell S. S., Whitehill A. B., Trapido-Rosenthal H. G., Ireland C. M., J. Nat. Prod., 60, 727-728 (1997).
4. Chehade C. C., Dias R. L. A., Berlinck R. G. S., Ferreira A. G., Costa L. V., Rangel M., Malpezzi E. L. A., Freitas J. C., Hajdu E., J. Nat. Prod., 60, 729-731 (1997).
5. Sheldrick G. M., "Crystallographic Computing 3" ed. by Sheldrick G. M., Goddard R., Oxford University Press, Oxford, 1985, pp. 175-189.
6. Crystallographic data for compound 1 reported in this paper have been deposited with the Cambridge Crystallographic Data Centre. Copies of the data can be obtained, free of charge, on application to Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: 144-(0)1223-336033 or e-mail: deposit@ccdc.cam.ac.uk).