T-cell responses and previous exposure to hepatitis C virus in indeterminate blood donors

Lancet

Volumn 365, Issue 9456, 2005, Pages 327-329

  Semmo, Nasser ^a   Barnes, Eleanor ^a   Taylor, Craig ^b   Kurtz, John ^b   Harcourt, Gillian ^a   Smith, Neil ^b   Klenerman, Paul ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE;

ADULT; AGED; ARTICLE; BLOOD DONOR; CONTROLLED STUDY; EX VIVO STUDY; EXPOSURE; FEMALE; HEPATITIS C VIRUS; HUMAN; IMMUNE RESPONSE; LABORATORY TEST; MALE; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 12344309155     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)70197-5     Document Type: Article

References (7)

1. Lauer GM, Walker BD. Hepatitis C virus infection. N Engl J Med. 345:2001;41-52
2. Takaki A, Wiese M, Maertens G, et al. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. Nat Med. 6:2000;578-582
3. National Blood Service Infection Surveillance. Monthly donation testing report, Health Protection Agency, UK. January, 2003.
4. Dufour DR, Talastas M, Fernandez MD, Harris B, Strader DB, Seeff LB. Low-positive anti-hepatitis C virus enzyme immunoassay results: an important predictor of low likelihood of hepatitis C infection. Clin Chem. 49:2003;479-486
5. Barnes E, Harcourt G, Brown D, et al. The dynamics of T-lymphocyte responses during combination therapy for chronic hepatitis C virus infection. Hepatology. 36:2002;743-754
6. Wedemeyer H, Mizukoshi E, Davis AR, Bennink JR, Rehermann B. Cross-reactivity between hepatitis C virus and influenza A virus determinant-specific cytotoxic T cells. J Virol. 75:2001;11392-11400
7. Day CL, Seth NP, Lucas M, et al. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest. 112:2003;831-842