-
1
-
-
1442333334
-
Specificity of charge-carrying residues in the voltage sensor of potassium channels
-
Ahern, C. A., and R. Horn. 2004. Specificity of charge-carrying residues in the voltage sensor of potassium channels. J. Gen. Physiol. 123:205-216.
-
(2004)
J. Gen. Physiol.
, vol.123
, pp. 205-216
-
-
Ahern, C.A.1
Horn, R.2
-
2
-
-
0037044784
-
Depolarization induces intersubunit cross-linking in a S4 cysteine mutant of the Shaker potassium channel
-
Aziz, Q. H., C. J. Partridge, T. S. Munsey, and A. Sivaprasadarao. 2002. Depolarization induces intersubunit cross-linking in a S4 cysteine mutant of the Shaker potassium channel. J. Biol. Chem. 277:42719-42725.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42719-42725
-
-
Aziz, Q.H.1
Partridge, C.J.2
Munsey, T.S.3
Sivaprasadarao, A.4
-
3
-
-
17044460689
-
Three transmembrane conformations and sequence-dependent displacement of the S4 domain in shaker K+ channel gating
-
Baker, O. S., H. P. Larsson, L. M. Mannuzzu, and E. Y. Isacoff. 1998. Three transmembrane conformations and sequence-dependent displacement of the S4 domain in shaker K+ channel gating. Neuron. 20:1283-1294.
-
(1998)
Neuron
, vol.20
, pp. 1283-1294
-
-
Baker, O.S.1
Larsson, H.P.2
Mannuzzu, L.M.3
Isacoff, E.Y.4
-
4
-
-
0034083955
-
Tethered blockers as molecular 'tape measures' for a voltage-gated K+ channel
-
Blaustein, R. O., P. A. Cole, C. Williams, and C. Miller. 2000. Tethered blockers as molecular 'tape measures' for a voltage-gated K+ channel. Nat. Struct. Biol. 7:309-311.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 309-311
-
-
Blaustein, R.O.1
Cole, P.A.2
Williams, C.3
Miller, C.4
-
5
-
-
84986512474
-
CHARMM: A program for macromolecular energy minimization and dynamic calculations
-
Brooks, B. R., R. E. Bruccoleri, B. D. Olafson, D. J. States, S. Swaminathan, and M. Karplus. 1983. CHARMM: a program for macromolecular energy minimization and dynamic calculations. J. Comput. Chem. 4:187-217.
-
(1983)
J. Comput. Chem.
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccoleri, R.E.2
Olafson, B.D.3
States, D.J.4
Swaminathan, S.5
Karplus, M.6
-
6
-
-
0345166933
-
Molecular movement of the voltage sensor in a K channel
-
Broomand, A., R. Mannikko, H. P. Larsson, and F. Elinder. 2003. Molecular movement of the voltage sensor in a K channel. J. Gen. Physiol. 122:741-748.
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 741-748
-
-
Broomand, A.1
Mannikko, R.2
Larsson, H.P.3
Elinder, F.4
-
7
-
-
0033576580
-
Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy
-
Cha, A., G. E. Snyder, P. R. Selvin, and F. Bezanilla. 1999. Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy. Nature. 402:809-813.
-
(1999)
Nature
, vol.402
, pp. 809-813
-
-
Cha, A.1
Snyder, G.E.2
Selvin, P.R.3
Bezanilla, F.4
-
8
-
-
0032478818
-
The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
-
Doyle, D. A., C. J. Morais, R. A. Pfuetzner, A. Kuo, J. M. Gulbis, S. L. Cohen, B. T. Chait, and R. MacKinnon. 1998. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science. 280:69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais, C.J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
9
-
-
0031877384
-
Structural models of the transmembrane region of voltage-gated and other K+ channels in open, closed, and inactivated conformations
-
Durell, S. R., Y. Hao, and H. R. Guy. 1998. Structural models of the transmembrane region of voltage-gated and other K+ channels in open, closed, and inactivated conformations. J. Struct. Biol. 121:263-284.
-
(1998)
J. Struct. Biol.
, vol.121
, pp. 263-284
-
-
Durell, S.R.1
Hao, Y.2
Guy, H.R.3
-
10
-
-
0035072555
-
Localization of the extracellular end of the voltage sensor S4 in a potassium channel
-
Elinder, F., P. Arhem, and H. P. Larsson. 2001a. Localization of the extracellular end of the voltage sensor S4 in a potassium channel. Biophys. J. 80:1802-1809.
-
(2001)
Biophys. J.
, vol.80
, pp. 1802-1809
-
-
Elinder, F.1
Arhem, P.2
Larsson, H.P.3
-
11
-
-
0034930982
-
S4 charges move close to residues in the pore domain during activation in a K channel
-
Elinder, F., R. Mannikko, and H. P. Larsson. 2001b. S4 charges move close to residues in the pore domain during activation in a K channel. J. Gen. Physiol. 118:1-10.
-
(2001)
J. Gen. Physiol.
, vol.118
, pp. 1-10
-
-
Elinder, F.1
Mannikko, R.2
Larsson, H.P.3
-
12
-
-
0344256586
-
The orientation and molecular movement of a k(+) channel voltage-sensing domain
-
Gandhi, C. S., E. Clark, E. Loots, A. Pralle, and E. Y. Isacoff. 2003. The orientation and molecular movement of a k(+) channel voltage-sensing domain. Neuron. 40:515-525.
-
(2003)
Neuron
, vol.40
, pp. 515-525
-
-
Gandhi, C.S.1
Clark, E.2
Loots, E.3
Pralle, A.4
Isacoff, E.Y.5
-
13
-
-
0036792837
-
Molecular models of voltage sensing
-
Gandhi, C. S., and E. Y. Isacoff. 2002. Molecular models of voltage sensing. J. Gen. Physiol. 120:455-463.
-
(2002)
J. Gen. Physiol.
, vol.120
, pp. 455-463
-
-
Gandhi, C.S.1
Isacoff, E.Y.2
-
14
-
-
0033576706
-
Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel
-
Glauner, K. S., L. M. Mannuzzu, C. S. Gandhi, and E. Y. Isacoff. 1999. Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel. Nature. 402:813-817.
-
(1999)
Nature
, vol.402
, pp. 813-817
-
-
Glauner, K.S.1
Mannuzzu, L.M.2
Gandhi, C.S.3
Isacoff, E.Y.4
-
16
-
-
0035859893
-
Periodic perturbations in Shaker K+ channel gating kinetics by deletions in the S3-S4 linker
-
Gonzalez, C., E. Rosenman, F. Bezanilla, O. Alvarez, and R. Latorre. 2001. Periodic perturbations in Shaker K+ channel gating kinetics by deletions in the S3-S4 linker. Proc. Natl. Acad. Sci. USA. 98:9617-9623.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9617-9623
-
-
Gonzalez, C.1
Rosenman, E.2
Bezanilla, F.3
Alvarez, O.4
Latorre, R.5
-
17
-
-
0025334586
-
Pursuing the structure and function of voltage-gated channels
-
Guy, H. R., and F. Conti. 1990. Pursuing the structure and function of voltage-gated channels. Trends Neurosci. 13:201-206.
-
(1990)
Trends Neurosci.
, vol.13
, pp. 201-206
-
-
Guy, H.R.1
Conti, F.2
-
18
-
-
0029188714
-
Structural models of Na+, Ca2+, and K+ channels
-
Guy, H. R., and S. R. Durell. 1995. Structural models of Na+, Ca2+, and K+ channels. Soc. Gen. Physiol. Ser. 50:1-16.
-
(1995)
Soc. Gen. Physiol. Ser.
, vol.50
, pp. 1-16
-
-
Guy, H.R.1
Durell, S.R.2
-
19
-
-
0000882125
-
Molecular model of the action potential sodium channel
-
Guy, H. R., and P. Seetharamulu. 1986. Molecular model of the action potential sodium channel. Proc. Natl. Acad. Sci. USA. 83:508-512.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 508-512
-
-
Guy, H.R.1
Seetharamulu, P.2
-
20
-
-
0032168179
-
The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge
-
Holmgren, M., K. S. Shin, and G. Yellen. 1998. The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge. Neuron. 21:617-621.
-
(1998)
Neuron
, vol.21
, pp. 617-621
-
-
Holmgren, M.1
Shin, K.S.2
Yellen, G.3
-
21
-
-
0002271340
-
The lipid-protein interface of a Shaker K(+) channel
-
Hong, K. H., and C. Miller. 2000. The lipid-protein interface of a Shaker K(+) channel. J. Gen. Physiol. 115:51-58.
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 51-58
-
-
Hong, K.H.1
Miller, C.2
-
22
-
-
0037198626
-
Crystal structure and mechanism of a calcium-gated potassium channel
-
Jiang, Y., A. Lee, J. Chen, M. Cadene, B. T. Chait, and R. MacKinnon. 2002. Crystal structure and mechanism of a calcium-gated potassium channel. Nature. 417:515-522.
-
(2002)
Nature
, vol.417
, pp. 515-522
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Cadene, M.4
Chait, B.T.5
MacKinnon, R.6
-
23
-
-
0038076054
-
X-ray structure of a voltage-dependent K+ channel
-
Jiang, Y., A. Lee, J. Chen, V. Ruta, M. Cadene, B. T. Chait, and R. MacKinnon. 2003a. X-ray structure of a voltage-dependent K+ channel. Nature. 423:33-41.
-
(2003)
Nature
, vol.423
, pp. 33-41
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Ruta, V.4
Cadene, M.5
Chait, B.T.6
MacKinnon, R.7
-
24
-
-
0038752614
-
The principle of gating charge movement in a voltage-dependent K+ channel
-
Jiang, Y., V. Ruta, J. Chen, A. Lee, and R. MacKinnon. 2003b. The principle of gating charge movement in a voltage-dependent K+ channel. Nature. 423:42-48.
-
(2003)
Nature
, vol.423
, pp. 42-48
-
-
Jiang, Y.1
Ruta, V.2
Chen, J.3
Lee, A.4
MacKinnon, R.5
-
25
-
-
0036204199
-
Determinants of 4-aminopyridine sensitivity in a human brain kv1.4 k(+) channel: Phenylalanine substitutions in leucine heptad repeat region stabilize channel closed state
-
Judge, S. I., J. Z. Yeh, J. E. Goolsby, M. J. Monteiro, and C. T. Bever, Jr. 2002. Determinants of 4-aminopyridine sensitivity in a human brain kv1.4 k(+) channel: phenylalanine substitutions in leucine heptad repeat region stabilize channel closed state. Mol. Pharmacol. 6:913-920.
-
(2002)
Mol. Pharmacol.
, vol.6
, pp. 913-920
-
-
Judge, S.I.1
Yeh, J.Z.2
Goolsby, J.E.3
Monteiro, M.J.4
Bever Jr., C.T.5
-
26
-
-
0035823555
-
Glycosylation increases potassium channel stability and surface expression in mammalian cells
-
Khanna, R., M. P. Myers, M. Laine, and D. M. Papazian. 2001. Glycosylation increases potassium channel stability and surface expression in mammalian cells. J. Biol. Chem. 276:34028-34034.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34028-34034
-
-
Khanna, R.1
Myers, M.P.2
Laine, M.3
Papazian, D.M.4
-
27
-
-
12444274301
-
Crystal structure of the potassium channel KirBac1.1 in the closed state
-
Kuo, A., J. M. Gulbis, J. F. Antcliff, T. Rahman, E. D. Lowe, J. Zimmer, J. Cuthbertson, F. M. Ashcroft, T. Ezaki, and D. A. Doyle. 2003. Crystal structure of the potassium channel KirBac1.1 in the closed state. Science. 300:1922-1926.
-
(2003)
Science
, vol.300
, pp. 1922-1926
-
-
Kuo, A.1
Gulbis, J.M.2
Antcliff, J.F.3
Rahman, T.4
Lowe, E.D.5
Zimmer, J.6
Cuthbertson, J.7
Ashcroft, F.M.8
Ezaki, T.9
Doyle, D.A.10
-
28
-
-
0042697277
-
Atomic proximity between S4 segment and pore domain in Shaker potassium channels
-
Laine, M., M. C. Lin, J. P. Bannister, W. R. Silverman, A. F. Mock, B. Roux, and D. M. Papazian. 2003. Atomic proximity between S4 segment and pore domain in Shaker potassium channels. Neuron. 39:467-481.
-
(2003)
Neuron
, vol.39
, pp. 467-481
-
-
Laine, M.1
Lin, M.C.2
Bannister, J.P.3
Silverman, W.R.4
Mock, A.F.5
Roux, B.6
Papazian, D.M.7
-
29
-
-
0030070436
-
Transmembrane movement of the shaker K+ channel S4
-
Larsson, H. P., O. S. Baker, D. S. Dhillon, and E. Y. Isacoff. 1996. Transmembrane movement of the shaker K+ channel S4. Neuron. 16:387-397.
-
(1996)
Neuron
, vol.16
, pp. 387-397
-
-
Larsson, H.P.1
Baker, O.S.2
Dhillon, D.S.3
Isacoff, E.Y.4
-
30
-
-
0344256589
-
Interaction between extracellular Hanatoxin and the resting conformation of the voltage-sensor paddle in Kv channels
-
Lee, H. C., J. M. Wang, and K. J. Swartz. 2003. Interaction between extracellular Hanatoxin and the resting conformation of the voltage-sensor paddle in Kv channels. Neuron. 40:527-536.
-
(2003)
Neuron
, vol.40
, pp. 527-536
-
-
Lee, H.C.1
Wang, J.M.2
Swartz, K.J.3
-
31
-
-
0033761957
-
A localized interaction surface for voltage-sensing domains on the pore domain of a K+ channel
-
Li-Smerin, Y., D. H. Hackos, and K. J. Swartz. 2000a. A localized interaction surface for voltage-sensing domains on the pore domain of a K+ channel. Neuron. 25:411-423.
-
(2000)
Neuron
, vol.25
, pp. 411-423
-
-
Li-Smerin, Y.1
Hackos, D.H.2
Swartz, K.J.3
-
32
-
-
0033981341
-
Alpha-helical structural elements within the voltage-sensing domains of a K(+) channel
-
Li-Smerin, Y., D. H. Hackos, and K. J. Swartz. 2000b. Alpha-helical structural elements within the voltage-sensing domains of a K(+) channel. J. Gen. Physiol. 115:33-50.
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 33-50
-
-
Li-Smerin, Y.1
Hackos, D.H.2
Swartz, K.J.3
-
33
-
-
0034130607
-
Localization and molecular determinants of the Hanatoxin receptors on the voltage-sensing domains of a K(+) channel
-
Li-Smerin, Y., and K. J. Swartz. 2000. Localization and molecular determinants of the Hanatoxin receptors on the voltage-sensing domains of a K(+) channel. J. Gen. Physiol. 115:673-684.
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 673-684
-
-
Li-Smerin, Y.1
Swartz, K.J.2
-
34
-
-
0035023528
-
Helical structure of the COOH terminus of S3 and its contribution to the gating modifier toxin receptor in voltage-gated ion channels
-
Li-Smerin, Y., and K. J. Swartz. 2001. Helical structure of the COOH terminus of S3 and its contribution to the gating modifier toxin receptor in voltage-gated ion channels. J. Gen. Physiol. 117:205-218.
-
(2001)
J. Gen. Physiol.
, vol.117
, pp. 205-218
-
-
Li-Smerin, Y.1
Swartz, K.J.2
-
36
-
-
0025706152
-
Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels
-
MacKinnon, R., and G. Yellen. 1990. Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels. Science. 250:276-279.
-
(1990)
Science
, vol.250
, pp. 276-279
-
-
MacKinnon, R.1
Yellen, G.2
-
37
-
-
0025818388
-
+ channels
-
+ channels. Proc. Natl. Acad. Sci. USA. 88:2931-2935.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2931-2935
-
-
McCormack, K.1
Tanouye, M.A.2
Iverson, L.E.3
Lin, J.-W.4
Ramaswami, M.5
McCormack, T.6
Campanelli, J.T.7
Mathew, M.K.8
Rudy, B.9
-
38
-
-
0038442831
-
A charged view of voltage-gated ion channels
-
Miller, C. 2003. A charged view of voltage-gated ion channels. Nat. Struct. Biol. 10:422-424.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 422-424
-
-
Miller, C.1
-
39
-
-
0032894975
-
Helical structure and packing orientation of the S2 segment in the Shaker K+ channel
-
Monks, S. A., D. J. Needleman, and C. Miller. 1999. Helical structure and packing orientation of the S2 segment in the Shaker K+ channel. J. Gen. Physiol. 113:415-423.
-
(1999)
J. Gen. Physiol.
, vol.113
, pp. 415-423
-
-
Monks, S.A.1
Needleman, D.J.2
Miller, C.3
-
40
-
-
0042707714
-
Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel
-
Neale, E. J., D. J. Elliott, M. Hunter, and A. Sivaprasadarao. 2003. Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel. J. Biol. Chem. 278:29079-29085.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29079-29085
-
-
Neale, E.J.1
Elliott, D.J.2
Hunter, M.3
Sivaprasadarao, A.4
-
41
-
-
0028998041
-
Electrostatic interactions of S4 voltage sensor in Shaker K+ channel
-
Papazian, D. M., X. M. Shao, S. A. Seoh, A. F. Mock, Y. Huang, and D. H. Wainstock. 1995. Electrostatic interactions of S4 voltage sensor in Shaker K+ channel. Neuron. 14:1293-1301.
-
(1995)
Neuron
, vol.14
, pp. 1293-1301
-
-
Papazian, D.M.1
Shao, X.M.2
Seoh, S.A.3
Mock, A.F.4
Huang, Y.5
Wainstock, D.H.6
-
42
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali, A., and T. L. Blundell. 1993. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234:779-815.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
44
-
-
0038329289
-
Structural biology: Life's transistors
-
Sigworth, F. J. 2003. Structural biology: Life's transistors. Nature. 423:21-22.
-
(2003)
Nature
, vol.423
, pp. 21-22
-
-
Sigworth, F.J.1
-
45
-
-
0242300127
-
Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit
-
Sokolova, O., A. Accardi, D. Gutierrez, A. Lau, M. Rigney, and N. Grigorieff. 2003. Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit. Proc. Natl. Acad. Sci. USA. 100:12607-12612.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12607-12612
-
-
Sokolova, O.1
Accardi, A.2
Gutierrez, D.3
Lau, A.4
Rigney, M.5
Grigorieff, N.6
-
46
-
-
0035078574
-
Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution
-
Sokolova, O., L. Kolmakova-Partensky, and N. Grigorieff. 2001. Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution. Structure (Camb). 9:215-220.
-
(2001)
Structure (Camb)
, vol.9
, pp. 215-220
-
-
Sokolova, O.1
Kolmakova-Partensky, L.2
Grigorieff, N.3
-
47
-
-
1142274549
-
A proton pore in a potassium channel voltage sensor reveals a focused electric field
-
Starace, D. M., and F. Bezanilla. 2004. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 427:548-553.
-
(2004)
Nature
, vol.427
, pp. 548-553
-
-
Starace, D.M.1
Bezanilla, F.2
-
48
-
-
0031474978
-
Voltage-dependent proton transport by the voltage sensor of the Shaker K+ channel
-
Starace, D. M., E. Stefani, and F. Bezanilla. 1997. Voltage-dependent proton transport by the voltage sensor of the Shaker K+ channel. Neuron. 19:1319-1327.
-
(1997)
Neuron
, vol.19
, pp. 1319-1327
-
-
Starace, D.M.1
Stefani, E.2
Bezanilla, F.3
-
49
-
-
0033818976
-
Voltage-dependent structural interactions in the Shaker K(+) channel
-
Tiwari-Woodruff, S. K., M. A. Lin, C. T. Schulteis, and D. M. Papazian. 2000. Voltage-dependent structural interactions in the Shaker K(+) channel. J. Gen. Physiol. 115:123-138.
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 123-138
-
-
Tiwari-Woodruff, S.K.1
Lin, M.A.2
Schulteis, C.T.3
Papazian, D.M.4
-
50
-
-
1942467020
-
Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges
-
Webster, S. M., D. Del Camino, J. P. Dekker, and G. Yellen. 2004. Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges. Nature. 428:864-868.
-
(2004)
Nature
, vol.428
, pp. 864-868
-
-
Webster, S.M.1
Del Camino, D.2
Dekker, J.P.3
Yellen, G.4
-
51
-
-
0030021584
-
Molecular basis of charge movement in voltage-gated sodium channels
-
Yang, N., A. L. George, Jr., and R. Horn. 1996. Molecular basis of charge movement in voltage-gated sodium channels. Neuron. 16:113-122.
-
(1996)
Neuron
, vol.16
, pp. 113-122
-
-
Yang, N.1
George Jr., A.L.2
Horn, R.3
-
52
-
-
0035499892
-
Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution
-
Zhou, Y., J. H. Morais-Cabral, A. Kaufman, and R. MacKinnon. 2001. Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature. 414:43-48.
-
(2001)
Nature
, vol.414
, pp. 43-48
-
-
Zhou, Y.1
Morais-Cabral, J.H.2
Kaufman, A.3
MacKinnon, R.4
|