Synthesis of a potent hNK-1 receptor antagonist via an SN2 reaction of an enantiomerically pure α-alkoxy sulfonate

Organic Letters

Volumn 7, Issue 1, 2005, Pages 55-58

  Nelson, Todd D ^a   Rosen, Jonathan D ^a   Smitrovich, Jacqueline H ^a   Payack, Joseph ^a   Craig, Bridgette ^a   Matty, Louis ^a   Huffman, Mark A ^a   McNamara, James ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ 1 RECEPTOR ANTAGONIST; SULFONIC ACID DERIVATIVE; SULFUR DERIVATIVE; NEUROKININ 1 RECEPTOR;

ACETALIZATION; ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; ENANTIOMER; HYDROLYSIS; KINETICS; STEREOCHEMISTRY; TECHNOLOGY; DRUG ANTAGONISM; STEREOISOMERISM; SYNTHESIS;

RECEPTORS, NEUROKININ-1; STEREOISOMERISM; SULFONIC ACIDS;

EID: 12344299765     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol047925u     Document Type: Article

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