Synthesis and analgesic action of N-(substituted-ethyl)pyrrole-3,4- dicarboximides

Farmaco

Volumn 60, Issue 1, 2005, Pages 15-22

  Malinka, W ^a   Kaczmarz, M ^a   Redzicka, A ^a   Filipek, B ^b   Sapa, J ^b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

3,4 pyrroledicarboximides; Analgesic activity

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; METHANOL; N [2 (1,2,3,4 TETRAHYDRO BETA CARBOLIN 2 YL)ETHYL] 2,5 DIMETHYL 1 PHENYLPYRROLE 3,4 DICARBOXIMIDE; N [2 (4 CYANO 4 PHENYPIPERIDIN 1 YL)ETHYL] 1 N BUTYL 2,5 DIMETHYLPYRROLE 3,4 DICARBOXIMIDE; N [2 (4 HYDROXY 4 PHENYLPIPERIDIN 1 YL)ETHYL] 1 N BUTYL 2,5 DIMETHYLPYRROLE 3,4 DICARBOXIMIDE; N [2 (4 PHENYL 1,2,3,6 TETRAHYDROPYRIDIN 1 YL)ETHYL] 2,5 DIMETHYL 1 PHENYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (2 FLUOROPHENYL)PIPERAZIN 1 YL]ETHYL] 2,5 DIMETHYL 1 PHENYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (2 FUROYL)PIPERAZIN 1 YL]ETHYL] 1 N BUTYL 2,5 DIMETHYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]ETHYL] 2,5 DIMETHYL 1 PHENYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (4 ACETYLPHENYL)PIPERAZIN 1 YL]ETHYL] 1 N BUTYL 2,5 DIMETHYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (4 BROMOPHENYL) 4 HYDROXYPIPERIDIN 1 YL]ETHYL] 1 N BUTYL 2,5 DIMETHYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (4 CHLOROPHENYL) 4 HYDROXYPIPERIDIN 1 YL]ETHYL] 2,5 DIMETHYL 1 PHENYLPYRROLE 3,4 DICARBOXIMIDE; N [2 [4 (DIPHENYLMETHYL)PIPERAZIN 1 YL]ETHYL 2,5 DIMETHYL 1 PHENYLPYRROLE 3,4 DICARBOXIMIDE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MALE; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING; WRITHING TEST;

ANALGESIA; ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; LETHAL DOSE 50; MALE; MICE; MOTOR ACTIVITY; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 12344299628     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.10.002     Document Type: Article

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