메뉴 건너뛰기




Volumn 52, Issue 4, 2004, Pages 271-280

A review of genetic and structural understanding of the role of myocilin in primary open angle glaucoma

Author keywords

GLC1A; Myocilin; Primary open angle glaucoma; TIGR MYOC

Indexed keywords

AMINO ACID; MYOCILIN; POLYMER; SIGNAL PEPTIDE;

EID: 12344297756     PISSN: 03014738     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (19)

References (69)
  • 1
    • 0027399771 scopus 로고
    • Open-angle glaucoma
    • Quigley HA. Open-angle glaucoma. New Engl J Med 1993;328:1097.
    • (1993) New Engl J Med , vol.328 , pp. 1097
    • Quigley, H.A.1
  • 2
    • 0029980777 scopus 로고    scopus 로고
    • Number of people with glaucoma worldwide
    • Quigley HA. Number of people with glaucoma worldwide. Br J Ophthalmol 1996;80:389-93.
    • (1996) Br J Ophthalmol , vol.80 , pp. 389-393
    • Quigley, H.A.1
  • 3
    • 0346319001 scopus 로고    scopus 로고
    • Molecular and cellular approaches to understand and treat some diseases of the eye
    • Balasubramanian D. Molecular and cellular approaches to understand and treat some diseases of the eye. Curr Sci 2002;82:948-57.
    • (2002) Curr Sci , vol.82 , pp. 948-957
    • Balasubramanian, D.1
  • 7
    • 0032513020 scopus 로고    scopus 로고
    • Gene structure and properties of TIGR, an olfactomedin related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells
    • Nguyen TD, Chen P, Huang WD, Chen H, Johnson DH, Polansky JR. Gene structure and properties of TIGR, an olfactomedin related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells. J Biol Chem 1998;273:6341-50.
    • (1998) J Biol Chem , vol.273 , pp. 6341-6350
    • Nguyen, T.D.1    Chen, P.2    Huang, W.D.3    Chen, H.4    Johnson, D.H.5    Polansky, J.R.6
  • 8
    • 17644433309 scopus 로고    scopus 로고
    • Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product
    • Polansky JR, Fauss DJ, Chen P, Chen H, Lutjen-Drecoll E, Johnson D, et al. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product. Ophthalmologica 1997;211:126-39.
    • (1997) Ophthalmologica , vol.211 , pp. 126-139
    • Polansky, J.R.1    Fauss, D.J.2    Chen, P.3    Chen, H.4    Lutjen-Drecoll, E.5    Johnson, D.6
  • 9
    • 0346670121 scopus 로고    scopus 로고
    • Evaluation and understanding of myocilin mutations in Indian primary open angle glaucoma patients
    • Kanagavalli J, Krishnadas SR, Eswari P, Krishnaswamy S, Sundaresan P. Evaluation and understanding of myocilin mutations in Indian primary open angle glaucoma patients. Mol Vis 2003;9:606-14.
    • (2003) Mol Vis , vol.9 , pp. 606-614
    • Kanagavalli, J.1    Krishnadas, S.R.2    Eswari, P.3    Krishnaswamy, S.4    Sundaresan, P.5
  • 10
    • 0003043766 scopus 로고    scopus 로고
    • Corticosteroid glaucoma
    • Ritch R, Shields MB and Krupin T, editors. St Louis; Mosby Year Book
    • Skuta GL, Morgan RK. Corticosteroid glaucoma. In: Ritch R, Shields MB and Krupin T, editors. The Glaucomas. St Louis; Mosby Year Book: 1996. pp 1177-88.
    • (1996) The Glaucomas , pp. 1177-1188
    • Skuta, G.L.1    Morgan, R.K.2
  • 11
    • 0029102995 scopus 로고
    • Glucocorticoids, ocular hypertension and glaucoma
    • Clark AF. Glucocorticoids, ocular hypertension and glaucoma. J Glaucoma 1995;4:354-69.
    • (1995) J Glaucoma , vol.4 , pp. 354-369
    • Clark, A.F.1
  • 12
    • 0012189825 scopus 로고    scopus 로고
    • Genetics and glaucoma
    • Ritch R, Shields MB and Krupin T, editors. St Louis: Mosby-Year Book, MO
    • Johnson AT, Alward WLM, Sheffield VC, Stone EM Genetics and glaucoma. In Ritch R, Shields MB and Krupin T, editors. The Glaucomas. St Louis: Mosby-Year Book, MO, 1996. pp 39-54.
    • (1996) The Glaucomas , pp. 39-54
    • Johnson, A.T.1    Wlm, A.2    Sheffield, V.C.3    Stone, E.M.4
  • 13
    • 0033623391 scopus 로고    scopus 로고
    • Muller cell protection of rat retinal ganglion cells from glutamate and nitric oxide neurotoxicity
    • Kawasaki A, Otori Y, Barnstable CJ. Muller cell protection of rat retinal ganglion cells from glutamate and nitric oxide neurotoxicity. Invest Ophthalmol Vis Sci 2000;41:3444-50.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3444-3450
    • Kawasaki, A.1    Otori, Y.2    Barnstable, C.J.3
  • 14
    • 0033926702 scopus 로고    scopus 로고
    • The genetics of open-angle glaucoma: The story of GLC1A and myocilin
    • Alward WLM. The genetics of open-angle glaucoma: The story of GLC1A and myocilin. Eye 2000;14:429-36.
    • (2000) Eye , vol.14 , pp. 429-436
    • Alward, W.L.M.1
  • 15
    • 0035168587 scopus 로고    scopus 로고
    • The TIGR/MYOC gene and glaucoma: Opportunities for new understandings
    • Tamm ER, Polansky JR. The TIGR/MYOC gene and glaucoma: Opportunities for new understandings. J Glaucoma 2001;10:S9-S12.
    • (2001) J Glaucoma , vol.10
    • Tamm, E.R.1    Polansky, J.R.2
  • 16
    • 0033926591 scopus 로고    scopus 로고
    • Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells
    • Polansky JR, Fauss DJ, Zimmerman CC. Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells. Eye 2002;14:503-514.
    • (2002) Eye , vol.14 , pp. 503-514
    • Polansky, J.R.1    Fauss, D.J.2    Zimmerman, C.C.3
  • 17
  • 18
    • 0030874913 scopus 로고    scopus 로고
    • Recent advances in molecular genetics of glaucoma
    • Sarfarazi M. Recent advances in molecular genetics of glaucoma. Human Molecular Genetics (Review) 1997;6:1667-77.
    • (1997) Human Molecular Genetics (Review) , vol.6 , pp. 1667-1677
    • Sarfarazi, M.1
  • 19
    • 0030942553 scopus 로고    scopus 로고
    • Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21
    • Stoilov I, Akarsu AN, Sarfarazi M. Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21. Hum Mol Genet 1997;6:641-47.
    • (1997) Hum Mol Genet , vol.6 , pp. 641-647
    • Stoilov, I.1    Akarsu, A.N.2    Sarfarazi, M.3
  • 21
    • 0027972492 scopus 로고
    • Mapping of a gene for autosomal dominant juvenile-onset open-angle glaucoma to chromosome 1q
    • Richards JE, Lichter PR, Boehnke M, Uro JL, Torrez D, Wong D et al. Mapping of a gene for autosomal dominant juvenile-onset open-angle glaucoma to chromosome 1q. Am J Hum Gene 1994;54:62-70.
    • (1994) Am J Hum Gene , vol.54 , pp. 62-70
    • Richards, J.E.1    Lichter, P.R.2    Boehnke, M.3    Uro, J.L.4    Torrez, D.5    Wong, D.6
  • 22
    • 0028332417 scopus 로고
    • Genetic linkage of autosomal dominant juvenile glaucoma to 1q21-q31 in three affected pedigrees
    • Wiggs JL, Haines JL, Paglinauan C, Fine A, Sporn C, Lou D. Genetic linkage of autosomal dominant juvenile glaucoma to 1q21-q31 in three affected pedigrees. Genomics 1994;21:299-303.
    • (1994) Genomics , vol.21 , pp. 299-303
    • Wiggs, J.L.1    Haines, J.L.2    Paglinauan, C.3    Fine, A.4    Sporn, C.5    Lou, D.6
  • 23
    • 0029003117 scopus 로고
    • A common gene for juvenile and adult-onset primary open-angle glaucomas confined on chromosome 1q
    • Morissette J, Cote G, Anctil JL, Plante M, Amyot M, Heon E, et al. A common gene for juvenile and adult-onset primary open-angle glaucomas confined on chromosome 1q. Am J Hum Genet 1995;56:1431-42.
    • (1995) Am J Hum Genet , vol.56 , pp. 1431-1442
    • Morissette, J.1    Cote, G.2    Anctil, J.L.3    Plante, M.4    Amyot, M.5    Heon, E.6
  • 25
    • 0028823359 scopus 로고
    • Statistical methods for polyploid radiation hybrid mapping
    • Lange K, Boehnke M, Cox DR, Lunetta KL. Statistical methods for polyploid radiation hybrid mapping. Genome Res 1995;5:136-50.
    • (1995) Genome Res , vol.5 , pp. 136-150
    • Lange, K.1    Boehnke, M.2    Cox, D.R.3    Lunetta, K.L.4
  • 26
    • 0031149050 scopus 로고    scopus 로고
    • A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: Molecular cloning, tissue expression and chromosomal mapping
    • Kubota R, Noda S, Wang Y, Minoshima S, Asakawa S, Kudoh J, et al. A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression and chromosomal mapping. Genomics 1997;41:360-69.
    • (1997) Genomics , vol.41 , pp. 360-369
    • Kubota, R.1    Noda, S.2    Wang, Y.3    Minoshima, S.4    Asakawa, S.5    Kudoh, J.6
  • 27
    • 0033753696 scopus 로고    scopus 로고
    • Localization of myocilin to the golgi apparatus in Schlemm's canal cells
    • O'Brien ET, Renx-O, Wang Y. Localization of myocilin to the golgi apparatus in Schlemm's canal cells. Invest Ophthalmol Vis Sci 2000;41:3842-49.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3842-3849
    • O'Brien, E.T.1    Renx, O.2    Wang, Y.3
  • 28
    • 4243544356 scopus 로고    scopus 로고
    • Myocilin: A molecular address for nascent junctions
    • (ARVO Abstract)
    • McKay BS, Roberts BC, Stamer WD. Myocilin: A molecular address for nascent junctions (ARVO Abstract). Invest Ophthalmol Vis Sci 2000;41:843.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 843
    • McKay, B.S.1    Roberts, B.C.2    Stamer, W.D.3
  • 29
    • 0032857679 scopus 로고    scopus 로고
    • Identification of the region in the N-terminal domain responsible for the cytoplasmic localization of MYOC/TIGR and its association with microtubules
    • Mertts M, Garfield S, Tanemoto K, Tomarev SI. Identification of the region in the N-terminal domain responsible for the cytoplasmic localization of MYOC/TIGR and its association with microtubules. Lab Invest 1999;79:1237-45.
    • (1999) Lab Invest , vol.79 , pp. 1237-1245
    • Mertts, M.1    Garfield, S.2    Tanemoto, K.3    Tomarev, S.I.4
  • 30
    • 0034858505 scopus 로고    scopus 로고
    • The role of MYOC/TIGR in glaucoma: Results of the glaucoma research foundation catalyst meeting in Berkeley
    • Tamm ER, Russell P. The role of MYOC/TIGR in glaucoma: Results of the glaucoma research foundation catalyst meeting in Berkeley. J Glaucoma 2001;10:329-39.
    • (2001) J Glaucoma , vol.10 , pp. 329-339
    • Tamm, E.R.1    Russell, P.2
  • 33
    • 0000657128 scopus 로고    scopus 로고
    • In vitro localization of Myocilin to the mitochondria of trabecular meshwork and corneal stroma cells (abstract)
    • Wentz-Hunter KK, Shimizu S, Yue BY. In vitro localization of Myocilin to the mitochondria of trabecular meshwork and corneal stroma cells (abstract). Invest Ophthalmol Vis Sci 2000;40:S197.
    • (2000) Invest Ophthalmol Vis Sci , vol.40
    • Wentz-Hunter, K.K.1    Shimizu, S.2    Yue, B.Y.3
  • 34
    • 0033940455 scopus 로고    scopus 로고
    • Myocilin and glaucoma
    • Johnson DH. Myocilin and glaucoma. Arch Ophthalmol 2000;118:974-78.
    • (2000) Arch Ophthalmol , vol.118 , pp. 974-978
    • Johnson, D.H.1
  • 35
    • 0030793108 scopus 로고    scopus 로고
    • Cloning and characterization of subtracted cDNAs from human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin
    • Ortego J, Escribano J, Coca-Prados M. Cloning and characterization of subtracted cDNAs from human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin. FEBS Lett 1997;413:349-53.
    • (1997) FEBS Lett , vol.413 , pp. 349-353
    • Ortego, J.1    Escribano, J.2    Coca-Prados, M.3
  • 37
    • 17944385621 scopus 로고    scopus 로고
    • Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)
    • Alward WL, Fingert JH, Coote MA, Johnson AT, Lerner SF, Junqua D, et al. Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A). N Engl J Med 1998;338:1022-7.
    • (1998) N Engl J Med , vol.338 , pp. 1022-1027
    • Alward, W.L.1    Fingert, J.H.2    Ma, C.3    Johnson, A.T.4    Lerner, S.F.5    Junqua, D.6
  • 38
    • 0034020149 scopus 로고    scopus 로고
    • Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma
    • Lam DS, Leung YF, Chua JK, Baum L, Fan DS, Choy KW, et al. Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci 2000;41:1386-91.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1386-1391
    • Lam, D.S.1    Leung, Y.F.2    Chua, J.K.3    Baum, L.4    Fan, D.S.5    Choy, K.W.6
  • 41
    • 0032491148 scopus 로고    scopus 로고
    • GLC1A mutations point to regions of potential functional importance on the TIGR/MYOC protein
    • Rozsa FW, Shimizu S, Lichter PR, Johnson AT, Othman MI, Scott K, et al. GLC1A mutations point to regions of potential functional importance on the TIGR/MYOC protein. Mol Vis 1998;4:20.
    • (1998) Mol Vis , vol.4 , pp. 20
    • Rozsa, F.W.1    Shimizu, S.2    Lichter, P.R.3    Johnson, A.T.4    Othman, M.I.5    Scott, K.6
  • 44
    • 19244382595 scopus 로고    scopus 로고
    • Myocilin Gln368STOP mutation and advanced age as risk factors for late-onset primary open-angle glaucoma
    • Angius A, Spinelli P, Ghilotti G, Casu G, Sole G, Loi A, et al. Myocilin Gln368STOP mutation and advanced age as risk factors for late-onset primary open-angle glaucoma. Arch Ophthalmol 2000;118:674-79.
    • (2000) Arch Ophthalmol , vol.118 , pp. 674-679
    • Angius, A.1    Spinelli, P.2    Ghilotti, G.3    Casu, G.4    Sole, G.5    Loi, A.6
  • 46
    • 0033278351 scopus 로고    scopus 로고
    • How does the trabecular meshwork regulate outflow? Clues from the vascular endothelium
    • Brandt JD, O'Donnell ME. How does the trabecular meshwork regulate outflow? Clues from the vascular endothelium. J Glaucoma 1999;8:328-39.
    • (1999) J Glaucoma , vol.8 , pp. 328-339
    • Brandt, J.D.1    O'Donnell, M.E.2
  • 49
    • 0032725031 scopus 로고    scopus 로고
    • A cellular assay distinguishes normal and mutant TIGR/MYOC protein
    • Zhou Z, Vollrath D. A cellular assay distinguishes normal and mutant TIGR/MYOC protein. Hum Mol Genet 1999;8:2221-28.
    • (1999) Hum Mol Genet , vol.8 , pp. 2221-2228
    • Zhou, Z.1    Vollrath, D.2
  • 50
    • 0035862866 scopus 로고    scopus 로고
    • Non-secretion of mutant proteins of the glaucoma gene Myocilin in cultured trabecular meshwork cells and in aqueous humor
    • Jacobson N, Andresws M, Shepard AR, Nishimura D, Searby C, Fingert JH, et al. Non-secretion of mutant proteins of the glaucoma gene Myocilin in cultured trabecular meshwork cells and in aqueous humor. Hum Mol Genet 2001;10:117-25.
    • (2001) Hum Mol Genet , vol.10 , pp. 117-125
    • Jacobson, N.1    Andresws, M.2    Shepard, A.R.3    Nishimura, D.4    Searby, C.5    Fingert, J.H.6
  • 51
    • 0344983870 scopus 로고    scopus 로고
    • Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells
    • Joe MK, Sohn S, Hur W, Moon Y, Choi YR, Kee C. Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells. Biochem Biophys Res Commun 2003;312:592-600.
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 592-600
    • Joe, M.K.1    Sohn, S.2    Hur, W.3    Moon, Y.4    Choi, Y.R.5    Kee, C.6
  • 52
    • 0034780081 scopus 로고    scopus 로고
    • Targeted disruption of the myocilin gene (MYOC) suggests that human glaucoma-causing mutations are gain of function
    • Kim BS, Savinova OV, Reedy MV, Martin J, Lun Y, Gan L, et al. Targeted Disruption of the Myocilin Gene (MYOC) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function. Mol Cell Biol 2001;21:7707-13.
    • (2001) Mol Cell Biol , vol.21 , pp. 7707-7713
    • Kim, B.S.1    Savinova, O.V.2    Reedy, M.V.3    Martin, J.4    Lun, Y.5    Gan, L.6
  • 53
    • 0031824572 scopus 로고    scopus 로고
    • Homozygotes carrying an autosomal dominant TIGR mutation do not manifest glaucoma
    • Morissette J, Clepet C, Moisan S, DuBois S, Winstall E, Vermeeren D, et al. Homozygotes carrying an autosomal dominant TIGR mutation do not manifest glaucoma. Nat Genet 1998;19:319-21.
    • (1998) Nat Genet , vol.19 , pp. 319-321
    • Morissette, J.1    Clepet, C.2    Moisan, S.3    Dubois, S.4    Winstall, E.5    Vermeeren, D.6
  • 54
    • 0019295852 scopus 로고
    • Metabolic interference and the + - Heterozygote. A hypothetical form of simple inheritance which is neither dominant nor recessive
    • Johnson WG. Metabolic interference and the + - heterozygote. A hypothetical form of simple inheritance which is neither dominant nor recessive Am J Hum Genet. 1980;32:374-86.
    • (1980) Am J Hum Genet , vol.32 , pp. 374-386
    • Johnson, W.G.1
  • 55
    • 0034842533 scopus 로고    scopus 로고
    • Characterization of myocilin-myocilin interactions
    • Fautsch MP, Johnson DH. Characterization of myocilin-myocilin interactions. Invest Ophthalmol Vis Sci 2001;42:2324-31.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2324-2331
    • Fautsch, M.P.1    Johnson, D.H.2
  • 57
    • 0037436854 scopus 로고    scopus 로고
    • Expression and characterization of the olfactomedin domain of human myocilin
    • Nagy I, Trexler M, Patthy L. Expression and characterization of the olfactomedin domain of human myocilin. Biochem Biophys Res Commun 2003;302:554-61.
    • (2003) Biochem Biophys Res Commun , vol.302 , pp. 554-561
    • Nagy, I.1    Trexler, M.2    Patthy, L.3
  • 60
    • 2342479087 scopus 로고    scopus 로고
    • Bioinformatic approaches for identification and characterisation of olfactomedin related genes with a potential in pathogenesis of ocular disorders
    • Mukhopadhyay A, Talukdar S, Bhattacharjee A, Ray K. Bioinformatic approaches for identification and characterisation of olfactomedin related genes with a potential in pathogenesis of ocular disorders. Mol Vis 2004;10:304-14.
    • (2004) Mol Vis , vol.10 , pp. 304-314
    • Mukhopadhyay, A.1    Talukdar, S.2    Bhattacharjee, A.3    Ray, K.4
  • 61
    • 0030586892 scopus 로고    scopus 로고
    • Localization of a locus (GLC1B) for adult-onset primary open angle glaucoma to the 2cen-q13 region
    • Stoilova D, Child A, Trifan OC, Crick RP, Coakes RL, Sarfarazi M. Localization of a locus (GLC1B) for adult-onset primary open angle glaucoma to the 2cen-q13 region. Genomics 1996;36:142-50.
    • (1996) Genomics , vol.36 , pp. 142-150
    • Stoilova, D.1    Child, A.2    Trifan, O.C.3    Crick, R.P.4    Coakes, R.L.5    Sarfarazi, M.6
  • 63
    • 0031851299 scopus 로고    scopus 로고
    • A third locus (GLC1D) for adult-onset primary open angle glaucoma maps to the 8q23region
    • Trifan OC, Traboulsi EI, Stoilova D, Alozie I, Nguyen R, Raja S, et al. A third locus (GLC1D) for adult-onset primary open angle glaucoma maps to the 8q23region. Am J Ophthalmol 1998;126:17-28.
    • (1998) Am J Ophthalmol , vol.126 , pp. 17-28
    • Trifan, O.C.1    Traboulsi, E.I.2    Stoilova, D.3    Alozie, I.4    Nguyen, R.5    Raja, S.6
  • 64
    • 18244385269 scopus 로고    scopus 로고
    • Adult onset primary open angle glaucoma caused by mutations in optinuerin
    • Rezaie T, Child A, Hitchings R, Brice G, Miller L, Coca-Prados M, et al. Adult onset primary open angle glaucoma caused by mutations in optinuerin. Science 2002;295:1077-79.
    • (2002) Science , vol.295 , pp. 1077-1079
    • Rezaie, T.1    Child, A.2    Hitchings, R.3    Brice, G.4    Miller, L.5    Coca-Prados, M.6
  • 67
    • 0015987426 scopus 로고
    • Prediction of protein conformation
    • Chou PY, Fasman GD. Prediction of protein conformation. Biochemistry 1974;13:222-45.
    • (1974) Biochemistry , vol.13 , pp. 222-245
    • Chou, P.Y.1    Fasman, G.D.2
  • 68
    • 0017873321 scopus 로고
    • Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
    • Garnier J, Osguthorpe DJ, Robson B. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J Mol Biol 1978;120:97-120.
    • (1978) J Mol Biol , vol.120 , pp. 97-120
    • Garnier, J.1    Osguthorpe, D.J.2    Robson, B.3
  • 69
    • 0029884694 scopus 로고    scopus 로고
    • GOR method for predicting protein secondary structure from amino acid sequence
    • Garnier J, Gibrat JR, Robson B. GOR method for predicting protein secondary structure from amino acid sequence. Methods Enzymol 1996;266:540-53.
    • (1996) Methods Enzymol , vol.266 , pp. 540-553
    • Garnier, J.1    Gibrat, J.R.2    Robson, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.