Bone marrow aplasia during hemodialysis successfully treated with cyclosporine. Report of one case;Aplasia medular tratada exitosamente con ciclosporina en un paciente en hemodiálisis crónica

Revista Medica de Chile

Volumn 132, Issue 8, 2004, Pages 989-994

  Vega S, Jorge ^a,b,c   De Los Angeles Rodríguez S, María ^a   Vásquez G, Alejandro ^a   Torres F, Carlos ^a  

^a HOSPITAL NAVAL ALMIRANTE NEF   (Chile)

^b UNIVERSIDAD DE VALPARAÍSO   (Chile)

^c Universidad de Valparaíso ^*  (Chile)

Author keywords

Anemia, aplastic; Bone marrow; Glomerulonephritis, IgA; Pancytopenia

Indexed keywords

CYCLOSPORIN; HEMOGLOBIN; IMMUNOGLOBULIN; KETOCONAZOLE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; STEROID;

ADULT; ARTICLE; BLOOD CELL COUNT; BONE MARROW APLASIA; BONE MARROW BIOPSY; CADAVER DONOR; CASE REPORT; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CYANOCOBALAMIN DEFICIENCY; FOLIC ACID DEFICIENCY; FOLLOW UP; GLOMERULONEPHRITIS; HEMATOCRIT; HEMODIALYSIS; HEMOLYTIC ANEMIA; HUMAN; HYPERPLASIA; HYPOPLASIA; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY GRAFT; LEUKOCYTE COUNT; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCYTOPENIA; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; THROMBOCYTE COUNT;

EID: 12344289078     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. BRODSKY RA. Biology and management of acquired severe aplastic anemia. Curr Opin Oncol 1998; 10: 95-9.
2. YOUNG NS. Acquired aplastic anemia. Ann Intern Med 2002; 136: 534-46.
3. FRICKHOFEN N, HEIMPEL H, KALTWASSER JP, SCHREZENMEIER H, GERMAN APLASTIC ANEMIA STUDY GROUP. Antithymocite globulin with or without cyclosporine A: 11 years follow up of a randomized trial comparing treatments of aplastic anemia. Blood 2003; 101: 1236-42.
4. BACIGALUPO A, BRUNO B, SARACCO P, DI BONA E, LOCASCIULLI A, LOCATELLI F ET AL. Antilymphocyte globulin, cyclosporine, prednisolone, and granulocyte colony stimulating factor for severe aplastic anemia: an update of the GITMO/EBMT study on 100 patients. European Group for Blood and Marrow Transplantation (EBMT) Working Party on Severe Aplastic Anemia and the Gruppo Italiano Trapianti di Midolio Osseo. Blood 2000; 95: 1931-4.
5. YOUNG N. Aplastic anemia. Lancet 1995; 346: 228.
6. GOTIC M, BASARA N, RLOVIC Z, ANTUNOVIC P, MARISAVLJEVIC D, BRKIC S. Successful treatment of refractory pure red cell aplasia secondary to chronic lymphocytic leukaemia with cyclosporine A: a correlation between clinical and in vitro effects. Nouv Rev Fr Hematol 1994; 36: 307-9.
7. TOHDA S, NARA N, TANIKAWA S, IMAI Y, MURAKAMI N, AOKI N. Pure red cell aplasia following autoimmune haemolytic anaemia. Cell mediated suppression of erythropoiesis as a possible pathogenesis of pure red cell aplasia. Acta Haematol 1992; 87: 98-102.
8. CASADEVALL N, NATAF J, VIRON V, KOLTA A, KILADJIAN J, MARTIN-DUPONT P. Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med 2002; 346: 469-75.
9. CASEDAVALL N. Antibodies against rHuEPO: native and recombinant. Nepbrol Dial Transplant 2002; 17 Suppl 5: 42-7.
10. CHNG W, TAN L, LIU T. Cyclosporine treatment for patients with CRF who developed pure red blood cell aplasia following EPO therapy. Am J Kidney Dis 2003; 41: 692-5.
11. NISTICO A, YOUNG NS. Gamma interferon gene expression in the bone marrow of patients with aplastic anemia. Ann Intern Med 1994; 120: 463.
12. SLOAND E, KIM S, MACIEJEWSKI JP, TISDALE J, FOLLMAN D, YOUNG NS. Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia. Blood 2002; 100: 1185.
13. ISMAIL M, GIBSON FM, GORDON-SMITH EC, RUTHEFORD TR. Bcl-2 and Bcl-x expression in the CD34+ cells of aplastic anaemia patients: relationship with increased apoptosis and upregulation of Fas antigen. Br J Haematol 2001; 113: 706.
14. VIBHUTI TRIPATHY NK, NITYANAND S. Massive apoptosis of bone marrow cells in aplastic anaemia. Br J Haematol 2002; 117: 993.
15. XU JL, NAGASAKA T, NAKASHIMA N. Involvement of cytotoxic granules in the apoptosis of aplastic anaemia. Br J Haematol 2003; 120: 850.
16. MACIEJEWSKI JP, SELLERI C, SATO T, ANDERSON S, YOUNG NS. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anemia. Br J Haematol 1995; 91: 245.
17. ROSENFELD S, FOLLMANN D, NÚÑEZ O, YOUNG NS. Antithymocyte Globulin and Cyclospdrine for Severe Aplastic Anemia: Association Between Hematologic Response and Long-term Outcome. JAMA 2003; 289: 1130.
18. GLUCKMAN E, ROKICKA-MILEWSKA R, HANN I, NIKIFORAKIS E, TAVAKOLI F, COHEN-SCALI S ET AL. European Group for Blood and Marrow Transplantation working Party for Severe Aplastic Anemia. Results and follow-up of a phase III randomized study of recombinant human-granulocyte stimulating factor as support for immunosuppressive therapy in patients with severe aplastic anaemia. Br J Haematol 2002; 119: 1075.
19. MARSH J, SCHREZENMEIER H, MARIN P, ILHAN O, LJUNGMAN P, MCCANN S ET AL. Prospective randomized multicenter study comparing cyclosporin alone versus the combination of antithymocyte globulin and cyclosporin for treatment of patients with nonsevere aplastic anemia. A report from the European Blood and Marrow Transplant (EBMT) Severe Aplastic Anaemia Working Party. Blood 1999; 93: 2191.
20. ENGELEN W, VERPOOTEN G, VAN DER PLANKEN M, HELBERT M, BOSMANS J, DE BROE M. Four cases of red blood cell aplasia in association with the use of mycophenolate mofetil in renal transplant patients. Clin Nephrol 2003; 60: 119-24.