Non-invasive measurements of bone strength: Promise and peril

Journal of Musculoskeletal Neuronal Interactions

Volumn 4, Issue 4, 2004, Pages 404-405

  Bouxsein, Mary L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CT; Bone strength; DXA; Microarchitecture; MRI; QCT

Indexed keywords

BIOLOGICAL MARKER; COLLAGEN;

ARTICLE; BIOMECHANICS; BONE DENSITY; BONE DISEASE; BONE MATRIX; BONE STRENGTH; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC IMAGING; DUAL ENERGY X RAY ABSORPTIOMETRY; FRACTURE; HUMAN; MEDICAL RESEARCH; NON INVASIVE MEASUREMENT; OSTEOPOROSIS; PREDICTION; RISK ASSESSMENT; VALIDATION PROCESS;

BONE AND BONES; DIAGNOSTIC IMAGING; FRACTURES, BONE; HUMANS; MAGNETIC RESONANCE IMAGING; OSTEOPOROSIS; STRESS, MECHANICAL; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT-BEARING;

EID: 12344286081     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Cummings SR, Bates D, Black DM. Clinical use of bone densitometry: scientific review. JAMA 2002; 288:1889-1897.
2. Bouxsein ML, Courtney AC, Hayes WC. Ultrasound and densitometry of the calcaneus correlate with the failure loads of cadaveric femurs. Calcif Tissue Int 1995; 56:99-103.
3. Bouxsein ML, Coan BS, Lee SC. Prediction of the strength of the elderly proximal femur by bone mineral density and quantitative ultrasound measurements of the heel and tibia. Bone 1999; 25:49-54.
4. Cheng XG, Nicholson PH, Boonen S, Lowet G, Brys P, Aerssens J, Van der Perre G, Dequeker J. Prediction of vertebral strength in vitro by spinal bone densitometry and calcaneal ultrasound. J Bone Miner Res 1997; 12:1721-1728.
5. Cheng XG, Lowet G, Boonen S, Nicholson PH, Brys P, Nijs J, Dequeker J. Assessment of the strength of proximal femur in vitro: relationship to femoral bone mineral density and femoral geometry. Bone 1997; 20:213-218.
6. Lochmuller EM, Zeller JB, Kaiser D, Eckstein F, Landgraf J, Putz R, Steldinger R. Correlation of femoral and lumbar DXA and calcaneal ultrasound, measured in situ with intact soft tissues, with the in vitro failure loads of the proximal femur. Osteoporos Int 1998; 8:591-598.
7. Lochmuller EM, Eckstein F, Kaiser D, Zeller JB, Landgraf J, Putz R, Steldinger R. Prediction of vertebral failure loads from spinal and femoral dual-energy X-ray absorptiometry, and calcaneal ultrasound: an in situ analysis with interact soft tissues. Bone 1998; 23:417-424.
8. Muller ME, Webber CE, Bouxsein ML. Predicting the failure load of the distal radius. Osteoporos Int 2003; 14:345-352.
9. Cummings SR, Karpf DB, Harris F, Genant HK, Ensrud K, LaCroix AZ, Black DM. Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with anti-resorptive drugs. Am J Med 2002; 112:281-289.
10. Delmas P, Seeman E. Changes in bone mineral density explain little of the reduction in vertebral or non-vertebral fracture risk with anti-resorptive therapy. Bone 2004; 34:599-604.
11. Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ. The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med 2003; 349:1207-1215.
12. Finkelstein JS, Hayes A, Hunzelman JL, Wyland JJ, Lee H, Neer RM. The effects of parathyroid hormone, alendronate, or both in men with osteoporosis. N Engl J Med 2003; 349:1216-1226.
13. Rehman Q, Lang TF, Arnaud CD, Modin GW, Lane NE. Daily treatment with parathyroid hormone is associated with an increase in vertebral cross-sectional area in postmenopausal women with glucocorticoid-induced osteoporosis. Osteoporos Int 2003; 14:77-81.
14. Newitt DC, Majumdar S, van Rietbergen B, von Ingersleben G, Harris ST, Genant HK, Chesnut C, Garnero P, MacDonald B. In vivo assessment of architecture and micro-finite element analysis derived indices of mechanical properties of trabecular bone in the radius. Osteoporos Int 2002; 13:6-17.
15. Majumdar S, Link TM, Augat P, Lin JC, Newitt D, Lane NE, Genant HK. Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group. Osteoporos Int 1999; 10: 231-239.
16. Wehrli FW, Saha PK, Gomberg BR, Song HK, Snyder PJ, Benito M, Wright A, Weening R. Role of magnetic resonance for assessing structure and function of trabecular bone. Top Magn Reson Imaging 2002; 13:335-355.
17. Pistoia W, van Rietbergen B, Lochmuller E, Lill C, Eckstein F, Ruegsegger P. Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone 2002; 30:842-848.
18. Crawford RP, Cann CE, Keaveny TM. Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography. Bone 2003; 33:744-750.