Factors influencing oligonucleotide stability in matrix-assisted laser desorption/ionization (MALDI) mass spectroscopy

International Journal of Mass Spectrometry and Ion Processes

Volumn 169-170, Issue , 1997, Pages 301-311

  Tang, Wei ^a   Krause, Joern ^a   Zhu, Lin ^a   Smith, Lloyd M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Fragmentation; MALDI MS; Matrix; N glycosidic bond; Oligonucleotide; Proton affinity; Protonation

Indexed keywords

EID: 12344283378     PISSN: 01681176     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0168-1176(97)00204-8     Document Type: Article

References (22)

1. M. Karas, D. Bachmann, U. Bahr, F. Hillenkamp, Int. J. Mass Spectrom. Ion Proc. 78 (1987) 53.
2. K. Tanaka, H. Waki, Y. Ido, S. Akita, Y. Yoshida, T. Yoshida, Rapid Commun. Mass Spectrom. 8 (1988) 151.
3. M.C. Fitzgerald, L. Zhu, L.M. Smith, Rapid Commun. Mass Spectrom. 7 (1993) 895.
4. D.M. Schieltz, P. Williams, in: Proceedings of the 42nd ASMS Conference on Mass Spectrometry and Allied Topics, Chicago, IL, 1994, p. 141.
5. S. Mouradian, D.R. Rank, L.M. Smith, Rapid Commun. Mass Spectrom. 10 (1996) 1475.
6. W. Tang, L. Zhu, L.M. Smith, Anal. Chem. 69 (1997) 302.
7. F. Kirpekar, E. Nordhoff, K. Kristiansen, P. Roepstorff, S. Hahner, F. Hillenkamp, Rapid Commun. Mass Spectrom. 9 (1995) 525.
8. E. Nordhoff, M. Karas, R. Cramer, S. Hahner, F. Hillenkamp, F. Kirpekar, A. Lezius, J. Muth, C. Meier, J.W. Engels, J. Mass Spectrom. 30 (1995) 99.
9. L. Zhu, G.P. Parr, M.C. Fitzgerald, C.M. Nelson, L.M. Smith, J. Am. Chem. Soc. 117 (1995) 6048.
10. K.J. Wu, A. Steding, C.H. Becker, Rapid Commun. Mass Spectrom. 7 (1993) 142.
11. I.G. Gut, S. Beck, Nucl. Acids Res. 23 (1995) 1367.
12. W. Tang, C.M. Nelson, L. Zhu, L.M. Smith, J. Am. Soc. Mass Spectrom. 8 (1997) 218.
13. M.C. Fitzgerald, G.R. Parr, L.M. Smith, Anal. Chem. 65 (1993) 3204.
14. S.A. McLuckey, G.J.V. Berkel, G.L. Glish, J. Am. Soc. Mass Spectrom. 3 (1992) 60.
15. D.P. Little, R.A. Chorush, J.P. Speir, M.W. Senko, N.L. Kelleher, F.W. McLafferty, J. Am. Chem. Soc. 116 (1994) 4893.
16. S.G. Lias, J.F. Liebman, R.D. Levin, J. Phys. Chem. 13 (1984) 695.
17. Z. Wu, C. Fenselau, Rapid Commun. Mass Spectrom. 6 (1992) 403.
18. F. Kirpekar, E. Nordhoff, K. Kristiansen, P. Roepstorff, A. Lezius, S. Hahner, M. Karas, F. Hillenkamp, Nucl. Acids. Res. 22 (1994) 3866.
19. Z. Olumee, M. Sadeghi, X. Tang, A. Vertes, Rapid Comm. Mass Spectrom. 9 (1995) 744.
20. C.M. Nelson, L. Zhu, W. Tang, L.M. Smith, K. Crellin, J. Berry, J.L. Beauchamp, 1996. Fragmentation mechanisms of oligonucleotides in MALDI mass spectrometry. Proc. SPIE-Int. Soc. Opt. Eng., 2680, 247-255.
21. F. Greco, A. Ligouri, G. Sindona, N. Uccella, J. Am. Chem. Soc. 112 (1990) 9092.
22. Mike C. Fitzgerald, Ph.D. Thesis, University of Wisconsin/ Madison, WI, 1994.